Clinical trials: Seasonal Allergies
Rhinitis, Allergic, Perennial and Seasonal, Rhinitis, Allergic
A Study to Compare the Efficacy and Safety of Fluticasone Furoate Nasal Sprays (FFNS) 55 Microgram (mcg) and 110 mcg in Chinese Pediatric Subjects With Allergic Rhinitis (AR)
This Phase IV interventional study is a multi-center, randomized, double-blind, placebo-controlled parallel study to evaluate the efficacy and safety of FFNS110 mcg and 55 mcg once daily versus vehicle placebo aqueous nasal spray…
- Trial name
- NCT02424539
- Testing
- FFNS
- Where
- 16 sites in China
- Volunteers
- 358 people
- Sponsor
- GlaxoSmithKline
Seasonal Rhinitis and/or Rhinoconjunctivitis, Birch Pollen Allergy
SUBLIVAC® Birch PROBE Study
Objective of the study is to show, on an exploratory basis, that treatment with SUBLIVAC Birch is also effective compared to treatment with Staloral Birch by means of reduction in allergic symptoms during nasal provocation in…
- Trial name
- NCT00932607
- Testing
- sublingual immunotherapy
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- HAL Allergy
Seasonal Allergic Rhinitis
Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)
This clinical validation study is aimed at establishing a birch pollen challenge in the Fraunhofer ECC in patients allergic to birch pollen.
- Trial name
- NCT01983865
- Testing
- Exposure to birch pollen
- Volunteers
- 18 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Rhinitis, Allergic, Seasonal
Single and Repeat Dose First Time in Human Study for an Intranasal H1/H3 Dual Antagonist in Healthy Male Subjects
This is a double-blind, placebo-controlled, randomized single dose escalation study and a double-blind, placebo-controlled, randomised parallel group 14-days once daily repeat dose study to investigate safety, tolerability and…
- Trial name
- NCT00694993
- Testing
- GSK1004723
- Where
- Germany
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Study of an Approved Drug in Patients With Asthma (0476-289)(COMPLETED)
The purpose of this study is to assess the efficacy and safety of an approved drug on asthma symptoms in patients with chronic asthma which is also active during the allergy season.
- Trial name
- NCT00092144
- Testing
- MK0476, montelukast sodium / Duration of Treatment: 4 weeks
- Volunteers
- 500 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Effect of Bacterial Lysate on Nasal Carriage of Staphylococcus Aureus
This study assesses the effectiveness of Polyvalent Mechanical Bacterial Lysate (PMBL-Ismigen) in reducing nasal methicillin-resistant Staphylococcus aureus (MRSA) colony growth in children with pollen allergic rhinitis (AR) aged…
- Trial name
- NCT04637425
- Testing
- Ismigen
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Lublin
Depression
Examining the Link Between Depression and Seasonal Allergies
This study will examine whether spring and fall seasonal depression in individuals with high sensitivity to pollen is linked to seasonal increases in tree and ragweed pollen.
- Trial name
- NCT00770068
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Seasonal Allergic Rhinoconjunctivitis
Safety Study of Grass Pollen-derived Peptides to Treat Seasonal Allergic Rhinoconjunctivitis
The purpose of this study is to determine whether the oral administration of grass pollen peptides is safe and effective in the treatment of allergic rhinitis.
- Trial name
- NCT00833066
- Testing
- gpASIT+TM
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- BioTech Tools S.A.
Seasonal Allergic Rhinitis
A Clinical Study on the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of SHR-1819 Injection in Patients With Seasonal Allergic Rhinitis
This is a trial to evaluate the safety and efficacy of SHR-1819 injection in the treatment of patients with seasonal allergic rhinitis.
- Trial name
- NCT07091357
- Testing
- SHR-1819 Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Seasonal Allergic Rhinitis
A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis
You are being asked to take part in a research study of COLD-fX, a product designed to boost the immune system. COLD-fX is an extract from the roots of North American ginseng and it may offer some benefit to people with seasonal…
- Trial name
- NCT00726401
- Testing
- COLD-fX
- Where
- 4 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Rhinitis, Seasonal, Allergic
StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study
This active vs active comparative trial will evaluate the safety and efficacy of incremental doses of atropine in combination with pseudoephedrine 120 mg/chlorpheniramine 8 mg in adult patients with a history of seasonal allergic…
- Trial name
- NCT02082054
- Testing
- PSE 120 mg, CM 8 mg, Atr 0.36 mg, PSE 120 mg, CM 8 mg, Atr 0.24 mg, PSE 120 mg, CM 8 mg, Atr 0.12 mg
- Where
- 4 sites in United States
- Volunteers
- 125 people
- Sponsor
- Magna Pharmaceuticals, Inc.
Hay Fever
Safety, Clinical Tolerability and Immunogenicity of Increasing Doses of gpASIT+TM
gpASIT+TM product is based on highly purified allergen fragments obtained from grass pollen. The purpose of this clinical trial is to confirm the safety, clinical tolerability and immunogenicity of increasing doses of gpASIT+TM…
- Trial name
- NCT02156791
- Testing
- gpASIT+TM
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- BioTech Tools S.A.
Seasonal Allergic Rhinitis
Vienna Challenge Chamber Study Using RV658 in Subjects With Allergic Rhinitis
RV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 ameliorates the nasal symptoms to low doses of grass…
- Trial name
- NCT01230619
- Testing
- RV568
- Where
- Austria
- Volunteers
- 75 people
- Sponsor
- Respivert Ltd
Seasonal Allergic Rhinitis
Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers
The current study will investigate nasal inflammatory markers obtained by filter paper collection techniques, in subjects with allergic rhinitis, determining the most appropriate time points and handling conditions, prior to…
- Trial name
- NCT00483353
- Testing
- Intra-nasal allergen challenge with Phleum pratense., Collection of nasal effluent using filter paper., Measurement of nasal congestion using acoustic rhinometry.
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Pfizer
Seasonal Allergic Rhinitis
A Study Evaluating the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
The purpose of this study is to determine if two allergy medications (formulated azelastine and fluticasone product) are more effective than placebo or either medication alone (azelastine or fluticasone)
- Trial name
- NCT00740792
- Testing
- azelastine HCl/fluticasone propionate, azelastine Hcl, fluticasone propionate
- Where
- 39 sites in United States
- Volunteers
- 776 people
- Sponsor
- Meda Pharmaceuticals
Rhinitis, Allergic, Seasonal
Efficacy and Safety of Levocetirizine and Fexofenadine in Reducing Symptoms of Seasonal Allergic Rhinitis
No information was yet available over the effect of levocetirizine in children under 12 years. The aim of this double-blind, placebo-controlled study was to assess the efficacy and safety of levocetirizine in children from 6 to…
- Trial name
- NCT00542607
- Testing
- levocetirizine dihydrochloride
- Volunteers
- 94 people
- Sponsor
- UCB Pharma
Seasonal Allergic Rhinitis
Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia
The purpose of this study is to explore the efficacy and safety of Ciclesonide Nasal Spray 200 microgram (mcg) once daily in the treatment of seasonal allergic rhinitis (SAR) in Russian participants.
- Trial name
- NCT02155881
- Testing
- Ciclesonide
- Where
- 5 sites in Russia
- Volunteers
- 80 people
- Sponsor
- AstraZeneca
Seasonal Allergic Rhinitis
Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR
The primary objective of this study was to compare the relative efficacy of Budesonide administered via Captisol-Enabled Budesonide nasal solution and Rhinocort Aqua in patients with seasonal allergic rhinitis (SAR) exposed to…
- Trial name
- NCT00938613
- Testing
- Budesonide
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Ligand Pharmaceuticals
Rhinoconjunctivitis
Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen Rhinoconjunctivitis
Due to the worldwide increasing prevalence of the allergic rhinoconjunctivitis, new therapeutical strategies are needed. The symptomatic treatment with topical and systemic antihistamines and corticosteroids are often…
- Trial name
- Ecorhino (NCT01013259)
- Testing
- Mutaflor
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Charite University, Berlin, Germany
Allergic Rhinitis Due to Pollen, Allergic Rhinitis With Asthma
Interaction Between Air Pollution, Pollens and Allergic Rhinitis
Seasonal allergic rhinitis has multiple consequences: sleep disturbances, fatigue, depressed mood, impaired quality of life and productivity, and co-morbid conditions such as asthma, which affects one third of AR patients.
- Trial name
- MISTRAL (NCT05007327)
- Testing
- Exposure to pollen and air pollution
- Where
- France
- Volunteers
- 1,215 people
- Sponsor
- MASK-air SAS