Clinical trials: Secondary Coronary Prevention
Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Elderly
Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial)
The CARTIER study is a randomized, multicenter, open-label clinical trial comparing, in elderly patients with cancer under anti-tumoral treatment, two different cardiotoxicity prevention strategies: primary (intensive…
- Conditions
- Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Elderly, Antineoplastic Agents, Cardiotoxicity
- Trial name
- CARTIER (NCT03711110)
- Testing
- Intensive cardiovascular monitoring, No intervention
- Where
- 14 sites in Spain
- Volunteers
- 514 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Myocardial Infarction (MI)
Omacor Plus Standard Therapies In Post Myocardial Infarction (MI) Subjects Evaluation: The OPTIMISE Observational Study
The OPTIMISE study is a prospective, multi-center, multi-national, structured data collection initiative, first compiling data on the current treatment of post myocardial infarction patients (screening-log) and then…
- Trial name
- NCT01632878
- Where
- Bulgaria
- Volunteers
- 1,531 people
- Sponsor
- Mylan Inc.
Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction
A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
The purpose of this pilot study is to evaluate the effectiveness of the active involvement of Community Pharmacists in improving adherence to medical prescriptions in patients with acute myocardial infarction (AMI), reducing the…
- Conditions
- Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
- Trial name
- IM-ADHERENCE (NCT03621111)
- Testing
- Patient-counseling, Patient self-administered questionnaire, Pills counts
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda ULSS 5 Polesana
Prediabetes, Coronary Artery Disease
Role of Rosiglitazone on Pre-Diabetes Mellitus and Coronary Artery Disease
Objectives: The investigators examined whether rosiglitazone, a thiazolidinedione (TZD), is beneficial for pre-diabetes mellitus (DM) adults with documented coronary artery disease (CAD).
- Conditions
- Prediabetes, Coronary Artery Disease, Insulin Resistance, Glucose Intolerance
- Trial name
- NCT01574820
- Testing
- rosiglitazone (4 mg)/day
- Volunteers
- 105 people
- Sponsor
- National Cheng-Kung University Hospital
Secondary Prevention of Coronary Heart Disease
The Gentle Cardiac Rehabilitation Study
The purpose of this study is to develop a tai-chi based exercise program designed for patients who recently had a heart attack and do not wish, or are unable, to attend traditional cardiac rehabilitation.
- Trial name
- NCT02165254
- Testing
- PLUS, LITE
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The Miriam Hospital
Myocardial Infarction, Acute Coronary Syndrome
Impact at One Year of a Secondary Prevention Educational Program on Cardiovascular Risk Factors
In secondary prevention, the beneficial role of cardiac rehabilitation programs after myocardial infarction, percutaneous coronary intervention or coronary artery bypass is now well established.
- Trial name
- OLIMPIC (NCT00758810)
- Where
- 4 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronary Artery Bypass Grafting, Medication Adherence
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Medication Adherence
The study is a randomized controlled trial, having a plan to recruit 1000 patients underwent coronary artery bypass grafting in 1 of 5 participating sites in 2015, and randomized to either the intervention group or control group…
- Conditions
- Coronary Artery Bypass Grafting, Medication Adherence, Mobile Applications
- Trial name
- MISSION-2 (NCT02432469)
- Testing
- APP intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Diabetes Mellitus, Type 2, Heart Failure
Randomised Trial of Health Coaching in Secondary Prevention of Diabetes and Heart Disease
A randomised trial with individual patients as units of observation will be carried out. Health coaching is used to modify health behaviour and thus improve disease control and health status, as well as use of health care…
- Conditions
- Diabetes Mellitus, Type 2, Heart Failure, Coronary Disease
- Trial name
- TerVa (NCT00552903)
- Testing
- Health coaching
- Where
- Finland
- Volunteers
- 1,500 people
- Sponsor
- Paijat-Hame Hospital District
Cardiovascular Diseases, Chronic Disease
Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.
The goal of this open label randomized controlled trial is to evaluate the efficacy of an intervention through health education based on the Chronic Care Model's implementation to increase therapeutic adherence in patients with…
- Conditions
- Cardiovascular Diseases, Chronic Disease, Secondary Prevention, Coronary Disease
- Trial name
- AT-PSC (NCT06510946)
- Testing
- (Health education program) To increase therapeutic adherence in patients with secondary prevention for cardiovascular disease
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Secondary Prevention, Stroke
Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)
To investigate the risk of major bleeding (including gastrointestinal and intracranial bleeding episodes) among new users of low-dose acetylsalicylic acid (ASA) in clinical practice
- Conditions
- Secondary Prevention, Stroke, Ischemic Heart Disease, Coronary Heart Disease
- Trial name
- EPISAT (NCT02550717)
- Testing
- Acetylsalicylic Acid (Aspirin, BAYE4465), Clopidogrel, Oral Anticoagulants, NSAIDs and SSRIs
- Where
- United Kingdom
- Volunteers
- 398,158 people
- Sponsor
- Bayer
Coronary Artery Disease
Secondary Prevention After Coronary Bypass Surgery
Despite immediate symptomatic success after coronary bypass surgery in patients with coronary artery disease, this effect is not sustained over time since risk factors for coronary artery disease are still in place.
- Trial name
- NCT00843089
- Testing
- Education
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Jeffrey Kramer, MD
Premature Coronary Heart Disease
Effectiveness of an AI-Enabled Stratified Management System for Premature Coronary Artery Disease
The goal of this clinical trial is to learn if an AI-enabled stratified management system (SMART-CHD) can improve post-discharge outcomes in adults aged 18-45 with premature coronary artery disease.
- Trial name
- SMART-CHD (NCT07031531)
- Testing
- AI-Enabled Stratified Management System, Usual Post-Discharge Care
- Where
- 16 sites in China
- Volunteers
- 4,900 people
- Sponsor
- China National Center for Cardiovascular Diseases
Arrhythmias, Cardiac, Atrioventricular Block
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical…
- Conditions
- Arrhythmias, Cardiac, Atrioventricular Block, Reduced Systolic Function, Atrial Fibrillation
- Trial name
- TREEBEARD (NCT06324682)
- Testing
- Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)
- Where
- 31 sites in Italy
- Volunteers
- 8,400 people
- Sponsor
- University Hospital of Ferrara
Acute Coronary Syndrome
ALLiance for sEcondary PREvention After an Episode of Acute Coronary Syndrome (ALLEPRE)
The purpose of the ALLEPRE trial is to compare the benefit offered by a structured, intensive and fully nurse-led intensive secondary prevention intervention programme with that offered by standard of care in a high-risk…
- Trial name
- ALLEPRE (NCT02522182)
- Testing
- Nurse-led Intensive Secondary Prevention Programme, Usual Treatment
- Where
- 7 sites in Italy
- Volunteers
- 2,060 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Stroke, Ischemic, Atrial Fibrillation
Wearable Devices for Secondary Prevention of Ischemic Stroke
Ischemic stroke is an important cause of death and disability in Western countries. Different risk factors have been identified such as hypertension, diabetes, dyslipidemia, smoke, atrial fibrillation, obesity, and sedentary.
- Trial name
- NCT04282993
- Testing
- Wearable devices for identifying and measuring risk factors for ischemic stroke, Standard of care monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Campus Bio-Medico University
Atrial Fibrillation, Risk Factors
Secondary Prevention of Atrial Fibrilation
Atrial fibrillation (AF) is the most common arrhythmia affecting over 3 million Americans and about 33.5 million individuals globally. The lifetime risk of developing AF is 1 in 4 for adults over age 40 years.
- Conditions
- Atrial Fibrillation, Risk Factors, Risk Reduction Behavior
- Trial name
- NCT03259893
- Testing
- AliveCor mobile ECG cardiac monitor, AF Program, Standard of care
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Saphenous Vein Graft Disease
Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis
Saphenous vein graft disease remains an unresolved medical problem. Many vein grafts occlude in the first year after bypass surgery, leading to adverse cardiovascular outcomes, including recurrent angina, myocardial infarction…
- Trial name
- TARGET (NCT02053909)
- Testing
- Aspirin, Ticagrelor
- Where
- 2 sites in United States, Canada
- Volunteers
- 250 people
- Sponsor
- Boca Raton Regional Hospital
Glucose Metabolism Disorders, Coronary Artery Disease
Acarbose and Secondary Prevention After Coronary Stenting
The purpose of this study is to determine whether the intervention for newly diagnosed abnormal glucose tolerance after coronary stenting will improve the long-term clinical outcome.
- Trial name
- NCT00221156
- Testing
- Acarbose
- Where
- 3 sites in Japan
- Volunteers
- 300 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Coronary Artery Disease
Community-based Precise Management for Patients With Coronary Artery Disease
The community-based precise management for patients with coronary artery disease study is a prospective, cluster-randomized, open-labeled trial.
- Trial name
- NCT05344053
- Testing
- Community-based precise management, Standard community-based management
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease
Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery
The time spent waiting for heart surgery can be extremely stressful. This programme aims to address this by providing a home-based, nurse-led support and education programme.
- Trial name
- NCT00124371
- Testing
- a nurse led home-based education and support programme
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust