Clinical trials: Secondary Headache Disorders
Cervicogenic Headache
Additional Effects of Sternocleidomastoid Release With SNAGS in the Management of Cervicogenic Headache
Cervicogenic headache is a common type of headache in adults which causes disability and difficulty in everyday activities. According to the latest International Headache Society model, cervicogenic headache (CGH) is a secondary…
- Trial name
- NCT06534606
- Testing
- Electrotherapy and physical agents, Headache SNAGs, Sternocleidomastoid Release
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
PDPH, Post Dural Puncture Headache
Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches
Post-dural puncture headache (PDPH) is an iatrogenic complication following a dural puncture, which may occur after lumbar puncture, spinal or epidural anesthesia.
- Trial name
- BRECHE (NCT07354464)
- Testing
- Sphenopalatine Ganglion Block, Blood patch
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine, Migraine With Aura
Ditan Acute tReatments: Effectiveness and Tolerability (DART)
The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of lasmiditan as acute migraine treatment in a cohort of episodic or chronic migraine patients.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- DART (NCT05903040)
- Testing
- Lasmiditan
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Post-Traumatic Headache
Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH
This is a United States Department of Defense funded Focused Program study that aims to identify mechanisms and predictors for persistent of post-traumatic headache attributed to mild traumatic brain injury, and identify methods…
- Trial name
- NCT04098250
- Testing
- Erenumab
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Cervicogenic Headache
Prevalence of Cervicogenic Headache in Lab Technicians
The purpose of the study is to determine the prevalence of cervicogenic headache among lab technicians
- Trial name
- NCT07067242
- Where
- Pakistan
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Post Traumatic Headache
Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)
Most individuals with mild traumatic brain injury (mTBI) experience post-traumatic headaches (PTH). Of PTH, 50% present with a migraine phenotype which is the most disabling type of PTH.
- Trial name
- NCT07191145
- Testing
- Eptinezumab
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cervicogenic Headaches
Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Cervicogenic Headache
The purpose of this research is to compare two different approaches for treating patients with cervicogenic headaches: non-thrust mobilization and exercise versus thrust manipulation and dry needling.
- Trial name
- NCT02373605
- Testing
- Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Post-Dural Puncture Headache
Long Term Outcomes Following a Post Dural Puncture Headache
Epidural analgesia is considered a gold standard method for treatment of labor pain. One of the major risks with epidural analgesia is an accidental dural puncture, which leads to a post dural puncture headache.
- Trial name
- NCT03550586
- Testing
- Questionaires
- Where
- 2 sites in Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Cervicogenic Headache
Cervicogenic Headache Dose-Response
This study will determine the number of visits to a chiropractor for spinal manipulation and light massage necessary for the optimal relief of cervicogenic headache (headache with associated neck pain).
- Trial name
- CGH D-R (NCT01530321)
- Testing
- Spinal Manipulation, Light Massage
- Where
- 2 sites in United States
- Volunteers
- 256 people
- Sponsor
- University of Western States
Post-Traumatic Headache, Head Trauma,Closed
Galantamine in the Treatment of Post-Traumatic Headache
Most patients with CPTH present with additional major cognitive, behavioral and somatic problems. Most drugs used currently have a negative influence on cognition.
- Conditions
- Post-Traumatic Headache, Head Trauma,Closed, Retention Disorders,Cognitive
- Trial name
- NCT00219869
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rapoport, Alan, M.D.
Effect of Physiotherapy on Cobb Angle in Patients With Cervicogenic Headache
Effect of Myofascial Release Technique Alone or Combined With Exercises on Cervical Cobb Angle, Sleep Quality, and Psychological Factors in Patients With Cervicogenic Headache
This study will investigate whether myofascial release therapy alone or in combination with therapeutic exercises can improve cervical spine alignment, measured by cervical Cobb angle on X-ray, in patients with cervicogenic…
- Trial name
- NCT07168512
- Testing
- Exercises (Endurance and strengthening), Myofascial release technique
- Where
- 3 sites in Palestinian Territories
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Post-Traumatic Headache, Traumatic Brain Injury
Acupuncture for Headache Post-Traumatic Brain Injury: A Feasibility Study
This study evaluates and addresses challenges to implementing an acupuncture intervention for adults who have headaches after sustaining a moderate traumatic brain injury.
- Trial name
- NCT04216173
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Washington
Cervicogenic Headache
Efficacy of Ultrasound-Guided Multifidus Cervicis Plan Block Vs Greater Occipital Nerve Block for Cervicogenic Headache
Background: Cervicogenic headache (CH) described as a chronic hemi-cranial pain resulted from a disorder of the cervical spine and its anatomic structures innervated by the C1, C2, and C3 cervical spinal nerves.
- Trial name
- UBLOC (NCT04454541)
- Testing
- Ultrasound-guided nerve block for headache management
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Abha International Private Hospital
Post-Dural Puncture Headache
The Occurrence of Post Dural Puncture Headache After Epidural Blood Patch
Spinal anesthesia is commonly used for cesarean section.However, the procedure is still have some adverse events such as high spinal block, nerve injuries or postdural puncture headache (PDPH).This is a potential complication of…
- Trial name
- NCT03080610
- Where
- 2 sites in Thailand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Medication Overuse Headache
Intravenous Treatments Used in Medication Overuse Headache Bridge Treatment
Medication overuse headache is the chronicity of headaches, which occurs more than 15 days a month, as a result of frequent use of painkillers, opioids or migraine attack drugs (ergotamine, triptan) in individuals with…
- Trial name
- NCT05608642
- Testing
- Intravenous hydration, Intravenous prednisolone, Intravenous lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Diskapi Teaching and Research Hospital
Postdural Puncture Headache
Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture Headache
In our study, we will compare a new route of nebulization for effectiveness between dexmedetomidine, neostigmine/atropine and saline placebo for females complained of postdural puncture headache (PDPH) after cesarean section.
- Trial name
- NCT04910477
- Testing
- Dexmedetomidine, Neostigmine/atropine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Occipital Neuralgia, Cervicogenic Headache
Greater Occipital Nerve Injection Study
This study is designed to answer the question of whether injection of the greater occipital nerve at its proximal origin, near the C2 vertebrae, using ultrasound guidance is effective in improving pain in human subjects.
- Trial name
- GON (NCT01988363)
- Testing
- GON injection at C2 location
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Post-Dural Puncture Headache, Low Pressure Headache
Non-Luer Butterfly Needle With One-way Valve for the Epidural Blood Patch: Does it Alter Blood Clotting?
The Department of Health recommends using equipment which prevents wrong route drug administration. However, the epidural blood patch requires equipment that connects to the intravenous and epidural route.
- Trial name
- NCT03420352
- Testing
- Thromboelastography
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Cervicogenic Headache
Instrument Based Fascial Abrasion Versus Myofascial Release Technique in Cervicogenic Headache Patients
Study will be randomized clinical trial. Data will be collected from non probability consecutive sampling technique. Total 44 participants from Rafiqa Hospital and District Headquarter (DHQ) Sargodha will be selected and randomly…
- Trial name
- NCT05249647
- Testing
- Instrument based Fascial abrasion technique, Myofascial release technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Unilateral Headache, Musculoskeletal Neck Pain
Effects of Cervical Manual Therapy on Cervicogenic Headache
The effects of cervical spine manual therapy, including mobilization and manipulation, on cervical spine range of motion, joint position sense, and balance is unknown among individuals with cervicogenic headache.
- Trial name
- NCT03385889
- Testing
- Cervical Spine Mobilization, Cervical Spine Manipulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Shenandoah University