Clinical trials: Secondary Headache Disorders
Post-Dural Puncture Headache
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
The purpose of this study is to evaluate Neostigmine and Glycopyrrolate to treat post-dural puncture headache (PDPH) to reduce the proportion of postpartum women with a PDPH requiring epidural blood patch (EBP) who developed a…
- Trial name
- NCT05116930
- Testing
- Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
Tissue Oxygenation
Postspinal Headache and Near Infrared Spectroscopy (NIRS)
Evaluation of the relationship between postspinal headache and near infrared spectroscopy in cesarean section patients
- Trial name
- NCT04187846
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Hakan Tapar
Post-Traumatic Headache
Hypersensitivity to PACAP-38 in Post-Traumatic Headache
The aim is to investigate whether signaling molecule PACAP-38 induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
- Trial name
- NCT05378061
- Testing
- Pituitary adenylate cyclase activating polypeptide-38
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Cervicogenic Headache
"Effectiveness of Kaltenborn Mobilization Techniques Versus Maitland Mobilization on Management of Cervicogenic Headache
EFFECTIVENESS OF KALTENBORN MOBILIZATION TECHNIQUES VERSUS MAITLAND MOBILIZATION ON MANAGEMENT OF CERVICOGENIC HEADACHE
- Trial name
- Effectiveness (NCT07820280)
- Testing
- Maitland mobilization, Kaltenborn
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Concussion Post Syndrome, Headaches Posttraumatic
Pediatric Concussion Outcomes
This is a randomized, placebo-controlled, double-blinded trial in which subjects with a post concussive headache meeting inclusion criterion will be assigned to one of two treatment groups: placebo or nortriptyline.
- Conditions
- Concussion Post Syndrome, Headaches Posttraumatic, Mild Traumatic Brain Injury
- Trial name
- PeCon (NCT04226365)
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Post-Concussion Syndrome, Post-Traumatic Headache
Acceptance and Commitment Therapy-based Rehabilitation of Post-concussion Symptoms
The investigators aim to evaluate effects of an outpatient rehabilitation program based on Acceptance and Commitment Therapy compared to usual care on function in patients with post-concussion syndrome (PCS) and post-traumatic…
- Trial name
- NCT04614922
- Testing
- Acceptance and Commitment Therapy
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- St. Olavs Hospital
Post-Dural Puncture Headache, Cesarean Section Complications
Effects of MET on PPDH, Neck Pain and Disability After Cesarean Section
The goal of this clinical trial is to determine the effect of Muscle Energy Techniques on post dural puncture headache, neck pain and disability after Cesarean Section. .
- Trial name
- NCT05834140
- Testing
- Traditional Physical Therapy, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Post-Traumatic Headache, Concussion, Mild
Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
To better understand the clinical characteristics and complex pathophysiological events that constitute persistent post-traumatic headache (PPTH) and to identify possible calcitonin gene-related peptide (CGRP) hypersensitivity in…
- Trial name
- NCT03791515
- Testing
- Calcitonin Gene-Related Peptide
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Cervicogenic Headache
CORRELATION BETWEEN FORWARD HEAD POSTURE, CERVICAL MUSCLES ENDURANCE, AND PROPRIOCEPTIVE FUCTIONS IN CERVICOGENIC HEADACHE AMONG LATE ADOLESCENT STUDENTS.
Forward Head Posture (FHP) is a common postural deviation characterized by anterior translation of the head relative to the trunk, which increases load on cervical muscles and joints.
- Trial name
- NCT07763886
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Delta University for Science and Technology
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Post-dural Puncture Headache, Post-dural Puncture Backache
Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)
Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP.
- Trial name
- LEAP (NCT02149680)
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Post-Traumatic Headache
Hypersensitivity to Phosphodiesterase 3 Inhibition in Post-Traumatic Headache
To investigate whether cilostazol (phosphodiesterase 3 inhibitor) induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
- Trial name
- NCT05595993
- Testing
- Cilostazol
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Cervicogenic Headache
Effects of Sustained Natural Appophyseal Glide Versus Rocababo 6x6 Program in Subjects With Cervicogenic Headache.
The purpose of this study is to investigate the effects of TMJ directed treatment approach using the Rocabado 6x6 program in patients with cervicogenic headache on the intensity of headache, function of the neck, and quality of…
- Trial name
- NCT05865808
- Testing
- cervical spine mobilization, Rocabado 6x6
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Posttraumatic Headache
Hypersensitivity to Adrenomedullin in Post-Traumatic Headache
Adrenomedullin is a neuropeptide implicated in the pathogenesis of headache. This study investigates whether adrenomedullin induces headache with migraine-like features in people with persistent post-traumatic headache (PTH)…
- Trial name
- NCT07059546
- Testing
- Adrenomedullin
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Posttraumatic Headache, Posttraumatic Stress Disorder
Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD
Post-Traumatic Stress Disorder (PTSD) and traumatic brain injury (TBI) with associated headache are amongst the most common injuries sustained by our deployed forces in Iraq and Afghanistan, as well as in more recent conflicts in…
- Trial name
- NCT06608277
- Testing
- Group A active comparator, Group B active comparator, Group C Experimental
- Where
- 3 sites in United States
- Volunteers
- 175 people
- Sponsor
- Northwestern University
Cervicogenic Headache
Comparison of the Effects of Mechanical Traction and Manual Traction on Cervicogenic Headache
52 people between the ages of 18-45 who were diagnosed with cervicogenic headache by the physician who applied to the Physical Medicine and Rehabilitation Department of Bursa VM Medical Park Hospital will be included in the…
- Trial name
- NCT05397977
- Testing
- mechanical traction group, manuel traction group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istinye University
Migraine, Migraine With Aura
Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of atogepant as preventive migraine treatment in a cohort of episodic or chronic migraine patients.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- STAR (NCT06414044)
- Testing
- Atogepant 60 mg
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Florence
Cervicogenic Headache, Cervicogenic Headaches
Comparison of Myofascial Release and Mulligan Concept Techniques in Patients With Cervicogenic Headache
The International Headache Society classifies cervicogenic headache as a secondary headache caused by a disorder of the cervical spine and its components.
- Trial name
- NCT06690411
- Testing
- Mulligan Concept, Myofascial Release Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Post-Dural Puncture Headache
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH
Management of postdural puncture headache (PDPH) has always been challenging for anesthesiologists. PDPH not only increases the misery of the patient, but the length of stay and overall cost of treatment in the hospital also…
- Trial name
- NCT05235256
- Testing
- bilateral sphenopalatine ganglion block, bilateral greater occipital nerve block, lidocaine plus dexamethasone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Post-Dural Puncture Headache, Sphenopalatine Ganglion Block
Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The objective of the study is to determine the effectiveness of Spheno-Palatine (SP) ganglion block to alleviate the pain of post-dural puncture headache (PDPH).
- Trial name
- NCT03430531
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center