Clinical trials: Secondary Hypertension
Pulmonary Hypertension, Valvular Heart Disease
Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease
The purpose of this study is to evaluate the clinical efficacy of the mid-term treatment with sildenafil in patients with persistent moderate or severe pulmonary hypertension (PH) after a heart valve intervention.
- Trial name
- SIOVAC (NCT00862043)
- Testing
- Sildenafil Citrate
- Where
- 18 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Sickle Cell Anemia, Pulmonary Hypertension
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension
This study will test whether inhaling nitric oxide (NO) gas mixed with room air can improve pulmonary hypertension (high blood pressure in the lungs) in patients with sickle cell anemia.
- Trial name
- NCT00023296
- Testing
- Nitric Oxide, INO Pulse - NO Delivery System
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Preeclampsia (PE)
Validation of the MaiRa Preeclampsia Test for Screening Early/Late Preeclampsia in First and Second Trimesters
Preeclampsia (PE) is a major obstetric complication with severe short- and long-term consequences for both mother and fetus. Early detection is critical to mitigate PE-related morbidity and mortality.
- Trial name
- iPregnostic (NCT06716242)
- Testing
- Peripheral blood collection
- Where
- 11 sites in Spain
- Volunteers
- 7,473 people
- Sponsor
- iPremom