Clinical trials: Secondary Hypertension
Cardiovascular Diseases, Hypertension
Secondhand Tobacco Smoke and Cardiovascular Disease
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic…
- Trial name
- NCT04715568
- Testing
- Losartan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Hypertension, Renal Function
The Vascular and Metabolic Effects of Sunitinib in Patients With Metastatic Renal Cell Carcinoma
Rationale: The introduction of angiogenesis inhibitors, like sunitinib and bevacizumab, has improved the outcome of patients with several types of cancer remarkably.
- Conditions
- Hypertension, Renal Function, Insulin Sensitivity, Renal Cell Carcinoma
- Trial name
- NCT01227213
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Radboud University Medical Center
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Hypertension, Pulmonary
The Exercise Capacity and Quality of Life in the Patients With IPAH and Secondary PH
Pulmonary hypertension (PH) is a progressive disease with high mortality rate, but due to the development of drugs, the prognosis of the disease has improved.
- Trial name
- NCT02647060
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- National Taiwan University Hospital
Hypertension Secondary
Telehealth-Enhanced Assessment and Management After Stroke-Blood Pressure
TEAMS-BP is a multicenter, participant-randomized controlled trial designed to compare the effectiveness of Intensive Tailored Telehealth Monitoring (ITTM) versus Intensive Clinic Management (ICM) on Blood Pressure (BP) control…
- Trial name
- TEAMS-BP (NCT05539443)
- Testing
- Intensive Clinic Management (ICM), Intensive tailored telehealth management (ITTM)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Wake Forest University Health Sciences
Hepatic Cirrhosis, Portal Hypertension
The Treatment of Hepatocirrhosis and Portal Hypertension
This study compare the efficiency of partial splenic embolization +endoscopical therapy with endoscopical therapy alone in gastroesophageal variceal haemorrhage accompanied with splenomegaly or hypersplenism of hepatocirrhosis…
- Trial name
- NCT02778425
- Testing
- Endoscopic therapy+ beta blockers, Endoscopic therapy+ PSE+beta blockers, beta blockers
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Yanjing Gao
Open Angle Glaucoma
Comparison of Efficacy Between Silicone Ahmed Glaucoma Valves and Second Trabeculectomy in Glaucoma Patients
In the management of open angle glaucoma, frequently more then one procedure is necessary to control the intra ocular pressure. There is still no consensus whether this second intervention should be a second trabeculectomy or a…
- Trial name
- NCT00665756
- Testing
- second Trabeculectomy, Ahmed Implant
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma
Protective Effect of Phenytoin on Glaucoma
since glaucoma is considered an optic neuropathy, new treatments for glaucoma are being continuously investigated, including neuroprotection.
- Conditions
- Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma, Narrow-Angle Glaucomas, Normal Tension Glaucoma
- Trial name
- NCT00739154
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Primary Hypertension, Secondary Hypertension
HaemoDYNAMICs in Primary and Secondary Hypertension
The primary aim of the present study was to examine the haemodynamic changes in primary hypertension and secondary hypertension (renal diseases, endocrine diseases, obesity-associated hypertension) with a non-invasive…
- Conditions
- Primary Hypertension, Secondary Hypertension, Aortic Stenosis, Renal Insufficiency
- Trial name
- DYNAMIC (NCT01742702)
- Testing
- Nitroglycerin 0.25 mg (single dose, no longer given since January 2017), Salbutamol 400 µg (single dose, no longer given since January 2017), L-arginine (10 min infusion, no longer given since January 2017)
- Where
- 2 sites in Finland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tampere University
Gastric Varices
Secondary Prophylaxis of Gastric Variceal Bleed
The purpose of this study is to study the efficacy of endoscopic cyanoacrylate injection versus balloon-occluded retrograde transvenous obliteration in the prevention of gastric variceal rebleeding and improvement in survival.
- Trial name
- NCT02468206
- Testing
- Balloon-occluded retrograde transvenous obliteration, Endoscopic cyanoacrylate injection, N-butyl-2-cyanoacrylate
- Where
- China
- Volunteers
- 64 people
- Sponsor
- West China Hospital
Cardiovascular Phenotype, Metabolic Phenotype
Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study
Background: Mosaicism is a condition in which cells within the same person have a different genetic makeup. Sometimes, a type of mosaicism called 45,X may not be discovered in a woman until she undergoes routine tests during…
- Conditions
- Cardiovascular Phenotype, Metabolic Phenotype, Hypertensive Disease, Psychological Phenotype
- Trial name
- NCT05548881
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Glaucoma
Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
- Trial name
- NCT07075718
- Testing
- Gen 2 Travoprost Intracameral Implant, Timolol eye drops 0.5%
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Glaukos Corporation
Pregnancy, Pre Eclampsia
Pre-Eclampsia Prediction By Doppler Screening Of Uterine Arteries And Angiogenic Factors In Second Trimester Of Pregnancy
BACKGROUND: Pre-eclampsia complicates about 2% of pregnancies. It accounts for at least 50 000 maternal deaths per year worldwide and is the second most common cause of maternal death in the developing world.
- Trial name
- NCT00725660
- Where
- Israel
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Endocrine and Metabolic Secondary Hypertension
Sacha Inchi Oil Supplementation in 3Hs
The objective of this study is to evaluate the effect of Sacha Inchi Oil supplementation among the 3Hs patients.
- Trial name
- NCT04920825
- Testing
- Sacha Inchi Oil softgel supplement, Corn oil softgel
- Where
- Malaysia
- Volunteers
- 54 people
- Sponsor
- Universiti Sains Malaysia
Glaucoma, Open-Angle, Glaucoma Secondary
The Outcome of Ahmed Glaucoma Valve in Difficult Glaucoma Cases
The clinical difference (mean IOP, success rate, and complications) on using S2 and FP7 models of Ahmed Glaucoma Valve that had similar dimensions and different materials used for their construction in one year follow up was…
- Conditions
- Glaucoma, Open-Angle, Glaucoma Secondary, Glaucoma, Neovascular
- Trial name
- NCT04214847
- Testing
- Ahmed Glaucoma Valve surgery
- Volunteers
- 1 people
- Sponsor
- Ain Shams University
Cirrhosis, Liver, Hypertension, Portal
Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding
Whether prophylactic antibiotics should be administered in the endoscopic secondary prevention of GVB or not is unclear. In this non-inferiority trial, we are aimed to evaluate whether prophylactic antibiotics are essential in…
- Conditions
- Cirrhosis, Liver, Hypertension, Portal, Variceal Hemorrhage
- Trial name
- NCT06437964
- Testing
- No use of prophylactic antibiotics, Prophylactic Antibiotics
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Post Coronary Artery Bypass Grafting, Hypertension
"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients
This study aims to evaluate the effect of an AI-assisted "Smart family doctor" digital health management tool on improving the control rates of hypertension, diabetes, and dyslipidemia in post-CABG (coronary artery bypass…
- Conditions
- Post Coronary Artery Bypass Grafting, Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- SMART (NCT06615609)
- Testing
- Smart family doctor, Health manager
- Where
- China
- Volunteers
- 536 people
- Sponsor
- China National Center for Cardiovascular Diseases
Esophageal and Gastric Varices
Carvedilol as an Adjunct to Endoscopic Cyanoacrylate Injection for Secondary Prophylaxis of Gastric Variceal Bleeding
Gastric variceal obturation is the current endoscopic therapy of choice for gastric variceal bleeding but is associated with a high rebleeding rate. Carvedilol is a potent non-selective β-blocker.
- Trial name
- NCT02504723
- Testing
- carvedilol, cyanoacrylate
- Where
- Taiwan
- Volunteers
- 121 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Stasis Dermatitis
Short and Ultra-short-pulse ND: YAG 1064nm Lasers (Omer Smart and Omer Premium) for Stasis Dermatitis
This study tests two types of lasers (ND YAG 1064 short and ultra-short pulses) to treat hyperchromic skin lesions secondary to venous hypertension (stasis dermatitis)
- Trial name
- SUPERSTAR (NCT06980961)
- Testing
- short-pulse ND: YAG 1064 laser, ultra-short-pulse ND: YAG 1064 laser, cold cream
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Science Valley Research Institute
Multidetector Computed Tomography, Pulmonary Embolism and Thrombosis
Lung Perfusion Measured With Dual-Energy CT in Patients With Chronic Thromboembolic Pulmonary Hypertension: Comparative Study With Right Heart Catheterization and V/Q
A comparative, observational, cross-sectional and prolective diagnostic test study, including patients that have had a right heart catheterization and were referred for a CT pulmonary angiography as part of their imaging workup…
- Conditions
- Multidetector Computed Tomography, Pulmonary Embolism and Thrombosis, Hypertension Pulmonary Secondary
- Trial name
- NCT03450304
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez