Clinical trials: Secondary Lymphedema
Lymphedema
Reduction of Lymphedema Secondary to Breast Cancer
This study evaluates the reduction of lymphedema and its complications in obese women treated with a muscle training and weight loss program as well as the improvement body composition, muscle strength, quality of life and…
- Trial name
- EJERDIETLIF (NCT04974268)
- Testing
- Specific supervised exercise and weight loss program
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Edema Due to Obstruction of Lymph Vessels or Excision of Lymph Nodes
Complete Decongestive Therapy Versus Compression Bandaging in Advanced Secondary Lymphedema
The purpose of this study is to: Find out the efficacy of using complete decongestive physiotherapy on limb volume in advanced secondary upper and lower extremity lymphedema patients.
- Trial name
- NCT04749342
- Testing
- Physiotherapy Treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahmed Mohamed Abdelrauf
Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary
Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery
Head and neck squamous cell carcinoma is one of the most common malignant tumors. At present, the standard treatment of head and neck squamous cell carcinoma recommended by the National Comprehensive Cancer Network(NCCN)…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Lymphedema, Secondary, Neck Lymph Dissection, Vascularized Lymph Node Transplantation
- Trial name
- NCT06815705
- Testing
- Vascularized lymphatic transplantation
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Primary Lower Limb Lymphedema, Secondary Lower Limb Lymphedema
Pilot Efficacy Study of the Stendo Pulsating Suit in Patient With Leg Lymphoedema
This study aims at evaluating the efficacy of the Stendo pulsating suit in patients with a leg lymphedema hospitalized for intensive Complex Decongestive Physiotherapy (CDP).
- Trial name
- NCT02234674
- Testing
- Current intensive CDP, intensive CDP where Stendo pulsating suit replaces pressotherapy
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Stendo
Primary Lymphedema, Secondary Lymphedema
Physical Therapies in the Decongestive Treatment of Lymphedema
The purpose of this multicenter randomised controlled study is to determine whether manual lymphatic drainage (MLD) brings any benefit when added to intermittent pneumatic compression (IPC) plus multilayer, multicomponent…
- Trial name
- NCT01748604
- Testing
- Manual Lymphatic Drainage (MLD), Generic intermittent pneumatic compression Device (IPC), multilayer, multicomponent bandages (MB)
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- Isabel Forner-Cordero, MD, PhD.
Lymphedema, Secondary
Effect of Lifestyle Intervention vs Physical Therapy Treatment in Patients With Secondary Lymphedema After Cancer
Participants with lymphedema secondary to cancer treatment will participate in a two week rehabilitation programme focusing on physical therapy treatment and a two week programme focusing on physical exercise.
- Trial name
- NCT04196725
- Testing
- Physical therapy treatment, Lifestyle treatment
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- Inland Norway University of Applied Sciences
Breast Neoplasms, Lymphedema
The Use of Selenium to Treat Secondary Lymphedema - Breast Cancer
The primary objective of this study to assess the effectiveness of selenium compared to placebo in reducing the lymphedema in-patients with breast cancer.
- Trial name
- NCT00188604
- Testing
- sodium selenite
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University Health Network, Toronto
Secondary Lymphedema
Lymphatic Function in Patients Who Have Undergone Breast Cancer Treatment
Protocol resume Swelling of tissue due to excess fluid, called lymphedema, is a common side effect of breast cancer treatment that requires lifelong treatment but in what way the treatment of breast cancer affects the lymphatic…
- Trial name
- LYFE-B (NCT03572998)
- Testing
- Indocyanine Green (ICG)
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- University of Aarhus
Lymphedema Arm, Lymphedema Due to Radiation
Effectiveness of a Therapeutic Exercise Program With Specific Upper Limb Exercises to Reduce Lymphedema and Neuropathy in Breast Cancer Patients: A Pre-post Study (LYNMA)
This study aims to evaluate the effectiveness of a therapeutic exercise program designed specifically for women with breast cancer.
- Conditions
- Lymphedema Arm, Lymphedema Due to Radiation, Lymphedema, Breast Cancer, Peripheral Neuropathy Due to Chemotherapy
- Trial name
- LYNMA (NCT07170631)
- Testing
- Therapeutic exercise
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Secondary Lymphedema
A Phase I Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema
Indicated for the Treatment of Secondary Lymphedema Associated with the Treatment of Breast Cancer. Primary objective is to evaluate the safety and tolerability of a single dose of Lymfactin® in patients with secondary lymphedema…
- Trial name
- NCT02994771
- Testing
- Lymfactin® [1 x 10E10 vp], Lymfactin® [1 x 10E11 vp]
- Where
- 3 sites in Finland
- Volunteers
- 15 people
- Sponsor
- Herantis Pharma Plc.
Lymphedema, Lymphedema Lower Extremity
Study to Evaluate the Safety and Effectiveness of Dayspring for Lower Extremity Lymphedema
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Koya Dayspring Active Wearable Compression Technology for Treating Lower Extremity Lymphedema
- Conditions
- Lymphedema, Lymphedema Lower Extremity, Chronic Venous Insufficiency, Secondary Lymphedema
- Trial name
- TIBER (NCT04897035)
- Testing
- Dayspring Active Wearable Compression System
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Koya Medical, Inc.
Lymphedema, Malignant Neoplasm
Recombinant Human Hyaluronidase in Treating Lymphedema in Patients With Cancer
This phase 1-2 trial studies the side effects and the best dose of recombinant human hyaluronidase and to see how well it works in treating lymphedema in patients with cancer.
- Trial name
- NCT01928030
- Testing
- recombinant human hyaluronidase
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Lymphedema
CVR Registry Evaluating Flexitouch Plus and Conservative Care vs Conservative Care Only for Treatment of Lymphedema
Subjects with lower extremity lymphedema will be prescribed, per standard of care, to either Flexitouch Plus with conservative care or conservative care only and be followed for 12 months.
- Trial name
- NCT04116099
- Testing
- Conservative care, Flexitouch Plus
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Tactile Medical
Lymphedema
Use of Reconstructive Microsurgery for the Treatment of Lymphedema
Lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in tissues, frequently resulting from oncological treatments, trauma, or cancer.
- Trial name
- NCT07889856
- Testing
- Surgery with and without the aid of Indocyanine Green (ICG)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Breast Cancer, Lymphedema
Effectiveness of Accelerated Intervention With Compression Sleeve in Mild and Moderate Breast Cancer-related Lymphedema
The purpose of this study is to determine whether accelerated treatment with custom-made compression sleeve is more effective than standard procedure in the treatment of mild and moderate arm lymphedema secondary to primary…
- Trial name
- NCT01954654
- Testing
- Custom-made compression sleeve and -gauntlet, Educational information, recommendation and instruction
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Mette Brodersen Jerver
Secondary Lymphedema, Breast Cancer
Supermicrosurgery for Breast Cancer Survivors With Lymphedema.
A randomised prospective investigation of volume and quality of life results with lymphovenous anastomosis in patients with unilateral arm lymphedema after breast cancer using Indocyanine Green lymphangiography and MD Anderson…
- Trial name
- NCT03578380
- Testing
- Surgery, Compression and drainage therapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Lymphedema, Obesity & Overweight
TECAR and ESWT in Obesity-Related Lower Limb Lymphedema
This randomized controlled trial evaluates the effectiveness of adding TECAR therapy or extracorporeal shock wave therapy (ESWT) to complex decongestive therapy (CDT) in the treatment of bilateral lower-limb lymphedema in…
- Trial name
- NCT07520942
- Testing
- Complex Decongestive Therapy, TECAR Therapy, Extracorporeal Shock Wave Therapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Applied Science Private University
Secondary Lymphedema
mRNA Therapy to Restore Lymphatic Flow in Secondary Lymphedema
Lymphedema is a common complication of breast cancer treatment, affecting approximately a quarter of patients. Those affected can have an uncomfortable, unsightly and sometimes functionally impaired limb prone to episodes of…
- Trial name
- LymphARN (NCT07793656)
- Testing
- APERNAVEC
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Toulouse
Lymphedema, Lymphedema of Face
A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema
To compare the effectiveness of an APCD to Usual Care in the management of lymphedema and fibrosis (LEF) in head and neck cancer (HNC) survivors.
- Conditions
- Lymphedema, Lymphedema of Face, Lymphedema, Secondary, Lymphedema Due to Radiation
- Trial name
- NCT04797390
- Testing
- Advanced Pneumatic Compression Device (APCD), Usual Care
- Where
- 10 sites in United States
- Volunteers
- 236 people
- Sponsor
- Tactile Medical
Secondary Lymphedema
Hyperbaric Oxygen Therapy to Reduce Lymphedema After Breast Cancer -an Explorative Clinical Trial
The purpose of this study is to examine if pressurechamber treatment (HBOT) can reduce early stages of breast cancer related lymphedema, and to explore the mechanisms involved in the disease progress.
- Trial name
- HBOT-LYCA (NCT02895724)
- Testing
- Medical Oxygen
- Volunteers
- 20 people
- Sponsor
- Danish Cancer Society