Clinical trials: Secondary Stroke
Acute Ischemic Stroke, Cancer
A Prospective Study to Observe Clinical Outcomes in Patients Receiving Antiplatelet or Anticoagulant Therapy for Cancer-Associated Acute Ischemic Stroke
The goal of this observational study is to learn about the effectiveness and safety of antiplatelet and anticoagulant treatments in people with a history of cancer who have acute ischemic stroke.
- Trial name
- NCT07845903
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Ischemic Stroke
ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion
Patients with tandem lesions (TL) are defined as patients with an acute ischemic stroke (AIS) with occlusion of an intracranial vessel of the anterior circulation and an occlusion or severe stenosis (70-99%) of the origin of the…
- Trial name
- ATILA (NCT05225961)
- Testing
- Tirofiban, Acetylsalicylic acid
- Where
- 13 sites in Spain
- Volunteers
- 240 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Stroke, Atrial Fibrillation
Know Your Pulse Post Stroke-Measurement of Peripheral Pulse for Detection of Atrial Fibrillation After Ischemic Stroke
Atrial fibrillation (AF) is the most common cause of cardioembolism and a leading cause of ischemic stroke. The diagnosis of AF after cerebral ischemia is difficult to establish even during the treatment at specialised stroke…
- Trial name
- NCT01858779
- Testing
- Measurement of peripheral pulse, 72h holter ECG
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Stroke
Secondary Prevention By Structured Semi-Interactive Stroke Prevention Package in INDIA (SPRINT INDIA) Study
Recurrent stroke, cardiovascular morbidity and mortality are important causes of poor outcome in patients with index stroke. According to the INTERSTROKE study, 80% of stroke are preventable due to the presence of modifiable risk…
- Trial name
- SPRINT (NCT03228979)
- Testing
- Structured Semi-Interactive Stroke Prevention Package
- Where
- India
- Volunteers
- 5,830 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Patent Foramen Ovale
Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)
Background and hypothesis: The appropriate treatment strategy for secondary stroke prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) remains challenging.
- Trial name
- NCT01550588
- Testing
- Device closure, Standard medical treatment
- Where
- 4 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- Jae-Kwan Song
Mobile Applications, Secondary Prevention
The Use of Samsung Health and ECG M-Trace Base II Applications in the Secondary Prevention After Stroke
The aim of the present study was to quantitatively assess the risk factors that may affect the re-occurrence of a CVD event and the use of a commercially available mobile application Samsung Health for the assessment of…
- Conditions
- Mobile Applications, Secondary Prevention, Stroke
- Trial name
- NCT04821518
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Stroke
A Feasibility Study of the Improving Health and Lifestyle Programme After Stroke (iHeLP)
The goal of this study is to learn if the Improving Healthand Lifestyle Programme (iHeLP) is feasible and acceptable to stroke survivors.
- Trial name
- NCT07761130
- Testing
- The Improving Health and Lifestyle Programme (iHeLP)
- Where
- 2 sites in Ireland
- Volunteers
- 19 people
- Sponsor
- University of Limerick
Acute Cerebrovascular Accident, Cerebral Edema
Study of Stroke Related Edema Treatments
Stroke remains the fourth leading cause of death in the United States (second worldwide) and a leading cause of long-term disability, resulting in total direct and indirect costs of approximately $73.7 billion annually.
- Trial name
- NCT01954290
- Testing
- Conivaptan, Hypertonic saline, Mannitol
- Sponsor
- University of Florida
Stroke, Atrial Fibrillation
Post-Embolic Rhythm Detection With Implantable Versus External Monitoring
The overall aim of this trial is to determine the most cost effective approach to diagnose paroxysmal atrial fibrillation (PAF) following transient ischemic attack (TIA) and stroke.
- Conditions
- Stroke, Atrial Fibrillation, Arrhythmias, Cardiac
- Trial name
- PERDIEM (NCT02428140)
- Testing
- Medtronic Reveal LINQ, Sorin Spiderflash-t
- Where
- 3 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Atrial Fibrillation, Stroke
WATCHMAN for Second Prevention of Stroke (WASPS)
To evaluate the effects of mechanical left atrial appendage (LAA) closure for secondary prevention of stroke in the patients with nonvalvular atrial fibrillation
- Trial name
- NCT03327350
- Testing
- WATCHMAN transplantation, Oral anticoagulant drugs
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Colchicine for Secondary Prevention After Ischemic Stroke (CHANCE-3 EX)
The role of colchicine in the secondary prevention of ischemic stroke has not been determinded. This multicenter, randomized, double-blind, placebo-controlled, event-driven clinical trial of CHANCE-3 EX was aimed to assess the…
- Trial name
- NCT07035405
- Testing
- Colchicine 0.5 mg
- Volunteers
- 7,500 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
Brazilian Version of an Intervention to Support Healthy Lifestyle Adoption Post-stroke - iVIDAVC
Introduction: Stroke presents a high global burden, particularly in low- and middle-income countries such as Brazil. Stroke secondary prevention, in which the adoption of healthy lifestyle behaviors is a key component, is an…
- Trial name
- NCT07809269
- Testing
- iVIDAVC, Telephone support
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Minas Gerais
Management of Ischemic Stroke, Medium Vessel Occlusion
PROMISE Registry: PROspective Study on Management of Ischemic Stroke Secondary to mEvo Registry
Investigators are conducting a real world, observational, prospective, multicenter study to better understand treatment for patients with MeVo and distal vessel occlusions in the U.S post publication of recent MeVO trials.
- Trial name
- NCT07746947
- Where
- United States
- Volunteers
- 652 people
- Sponsor
- Indiana University
Embolic Stroke of Undetermined Source
Embolic Stroke of Undetermined Source, Continuous Electrocardiography and Transthoracic ECHOcardiography in Hospitalized Patients With Ischemic Stroke
Transthoracic echocardiography (TTE) is recommended in patients with ischemic stroke when cardiac etiology is suspected to help plan secondary stroke management.
- Trial name
- ESECHO (NCT04808258)
- Testing
- C3+ Holter Monitor
- Where
- 2 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Herlev and Gentofte Hospital
Stroke, Transient Ischemic Attack
Comprehensive Post-Acute Stroke Services
The purpose of this pragmatic study is to investigate whether implementation of a comprehensive post-acute stroke service model that integrates Early Supported Discharge (ESD) and Transitional Care Management (TCM) for stroke…
- Trial name
- COMPASS (NCT02588664)
- Testing
- COMPASS Intervention
- Where
- 40 sites in United States
- Volunteers
- 6,024 people
- Sponsor
- Wake Forest University Health Sciences
Cerebral Infarction
Comparison of Triflusal and Clopidogrel in Secondary Prevention of Stroke Based on the Genotyping
The purpose of this study is to compare the preventive effect of stroke between triflusal and clopidogrel in ischemic stroke patient based on the cytochrome P450 2C19 (CYP2C19) polymorphism.
- Trial name
- MAESTRO (NCT01174693)
- Testing
- Triflusal, Clopidogrel
- Where
- 18 sites in South Korea
- Volunteers
- 795 people
- Sponsor
- Gangnam Severance Hospital
Non-valvular Atrial Fibrillation, Embolic Stroke
Left Atrial Appendage Closure as Secondary Prevention of Atrial Fibrillation-related Embolic Events
This clinical study is a prospective, multi-center, non-interventional study designed to investigate the safety and effectiveness of percutaneous LAA appendage closure by using LAmbre™ Left Atrial Appendage Occluder System.
- Trial name
- NCT04559243
- Testing
- Transthoracic Echocardiography
- Where
- 5 sites in China
- Volunteers
- 579 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Stroke, Stroke, Acute
A Multisite Exploration of Balance Perturbations With and Without Body Weight Support
ZeroG is an FDA-listed robotic body weight support system (BWSS). Mounted on an overhead track, patients are fitted in a harness system tethered to said track, and are able to practice gait and balance activities without the risk…
- Conditions
- Stroke, Stroke, Acute, Balance; Distorted, Balance; Impairment
- Trial name
- NCT05110300
- Testing
- Body weight support system control group, Body weight support system with balance perturbations
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Gaylord Hospital, Inc
Stroke
Iron Chelation in the Prevention of Secondary Degeneration After Stroke
Stroke is a major cause of disability over the world. While acute therapies have made huge progresses, the number of survivors leaving with clinical consequences of stroke is increasing.
- Trial name
- CHEL-IC (NCT05111821)
- Testing
- Magnetic Resonance Imaging (MRI), Deferiprone treatment
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Bordeaux
Ischemic Stroke, TIA
Stroke Card Long-term Follow-Up
We undertook the STROKE-CARD trial (NCT02156778) between 2014 and 2018 with follow-up until 2019 to evaluate the efficacy of the Post-Stroke disease-management program STROKE-CARD care.
- Trial name
- NCT04205006
- Where
- 2 sites in Austria
- Volunteers
- 1,000 people
- Sponsor
- Medical University Innsbruck