Clinical trials: Secondary Stroke
Stroke, Obesity
Secondary Prevention of Stroke Through Non-drug Therapeutic Weight Reduction
SCENARIO is a trial to investigate the role of non-drug weight reduction in secondary prevention of stroke. It is a single-blinded, randomized, controlled multicentre trial with two arms.
- Trial name
- SCENARIO (NCT01721538)
- Testing
- Weight reduction program, Lecture on healthy nutrition
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Philipps University Marburg
Stroke, Transient Ischemic Attack
The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial
The purpose of the study is to evaluate the efficacy and safety of Butylphthalide Soft Capsules (En Bi Pu, NBP) in Secondary Prevention of Ischemic Stroke
- Trial name
- ESCAPE (NCT00724724)
- Testing
- Butylphthalide Soft Capsules, Aspirin
- Where
- 50 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation
Non-Interventional Study Describing Direct Costs Related to Anti-coagulation Treatment
To describe the direct costs related to warfarin/apixaban treatment
- Trial name
- NCT04435769
- Where
- Czechia
- Volunteers
- 109 people
- Sponsor
- Pfizer
Ischemic Attack, Transient, Stroke
Colchicine for Prevention of Vascular Inflammation in Non-cardio Embolic Stroke
This study evaluates the use of Colchicine in adults over 40 years of age who have suffered an ischaemic stroke or transient ischaemic attack NOT caused by cardiac embolism or other defined causes.
- Trial name
- CONVINCE (NCT02898610)
- Testing
- Colchicine
- Where
- 145 sites in Belgium, Canada and 12 more
- Volunteers
- 3,154 people
- Sponsor
- University College Dublin
Clopidogrel Resistance, Secondary Stroke Prevention
Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant
The purpose of this study is to determine whether adding primidone will improve the metabolism of clopidogrel thereby increasing metabolite levels within the blood stream and platelet response to clopidogrel in patients who were…
- Trial name
- NCT02008123
- Testing
- Primidone
- Where
- United States
- Sponsor
- Dent Neuroscience Research Center
Cerebral Infarction
Acupuncture Lowering Blood Pressure for Secondary Prevention of Stroke
This study evaluate the effects of acupuncture method on the recurrence of ischemic stroke patients.Half of participants will receive "Huo Xue San Feng" acupuncture combining 1 antihypertensive medication on the routine ischemic…
- Trial name
- NCT02967484
- Testing
- acupuncture
- Where
- 5 sites in China
- Volunteers
- 480 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Intracerebral Hemorrhage, Stroke
The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial
The purpose of this academic lead study is to determine if a treatment strategy of early intensive blood pressure (BP) lowering compared to conservative BP lowering policy in patients with elevated blood pressure within 6 hours…
- Conditions
- Intracerebral Hemorrhage, Stroke, Hypertension
- Trial name
- INTERACT2 (NCT00716079)
- Testing
- Blood pressure management policies
- Where
- 62 sites in United States, Argentina and 17 more
- Volunteers
- 2,839 people
- Sponsor
- The George Institute
Stroke, Transient Ischemic Attack
Determinants of Adherence to Post-stroke/Transient Ischemic Attack Secondary Prevention Treatment: Cohort Study in the Rhône
The effectiveness of emergency management of acute ischemic stroke has improved considerably in recent years with thrombolysis and more recently thrombectomy.
- Trial name
- OBSTACLE (NCT03153020)
- Testing
- Patients with stroke or transient ischemic attack
- Where
- France
- Volunteers
- 633 people
- Sponsor
- Hospices Civils de Lyon
Stroke
Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke Patients
Rehabilitative treatment in stroke survivors has shown to be effective in improving functional outcome and reducing dependency. Plasticity of the central nervous system, along with coping strategies and adaptations, seems to play…
- Trial name
- NCT00967408
- Testing
- Escitalopram, Rehabilitative treatment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Atrial Fibrillation, Stroke
LAA Excision With AF Ablation Versus Oral Anticoagulants for Secondary Prevention of Stroke
This cohort study aims to evaluate thoracoscopic left atrial appendage excision plus atrial fibrillation ablation versus oral anticoagulants for the prevention of stroke and non-central nervous systemic embolism in patients with…
- Conditions
- Atrial Fibrillation, Stroke, Systemic Embolism
- Trial name
- 5A (NCT02478294)
- Testing
- Thoracoscopic LAA Excision plus AF Ablation, Warfarin or Novel Oral Anticoagulants
- Where
- China
- Volunteers
- 474 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cryptogenic Stroke, Atrial Fibrillation
Stroke of Unknown Cause in Women: The Impact of Long-term Heart Monitoring on Stroke Recurrence
The goal of this observational study is to investigate sex - differences in detection rate of atrial fibrillation after cryptogenic stroke (embolic stroke of unknown cause) - using an implantable cardiac rhythm monitor - and the…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Implantable Cardiac Monitor, Secondary Stroke Prevention
- Trial name
- STROKEWISE (NCT07194811)
- Where
- Norway
- Volunteers
- 1,400 people
- Sponsor
- University Hospital, Akershus
Myocardial Infarction, Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack)
Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Primary and Secondary Prevention of Diseases of the Heart and Blood Vessels
This study aims to gather information to what extent patients follow the treatment regimen of low-dose aspirin for primary and secondary prevention of diseases of the heart and blood vessels.
- Conditions
- Myocardial Infarction, Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack), Unstable Angina, Angina
- Trial name
- PALACE (NCT04097912)
- Testing
- Acetylsalicylic Acid (Aspirin, BAYE4465)
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Chronic Post-stroke Headache
TMS and Exercise for Post-stroke Pain
There are over 7 million people living with stroke in the United States. Per year, approximately 17,000 Veterans are admitted to the VA for acute stroke. Chronic pain after stroke can occur between 10-50% of stroke survivors.
- Trial name
- NCT04672044
- Testing
- Active rTMS and exercise
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Acute Ischemic Stroke, Reperfusion Injury
Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study
Infarct growth (IG), Hemorrhagic Transformation (HT) and Cerebral Edema (CE) can be considered pivotal phenomena of clinical deterioration following an acute ischemic stroke.
- Conditions
- Acute Ischemic Stroke, Reperfusion Injury, Cerebral Edema, Hemorrhagic Transformation Due to Acute Stroke
- Trial name
- NIMBLE (NCT07422636)
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- University of Florence
Transient Ischemic Attack, Non-disabling Stroke
Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
The objective of the Program of Rehabilitative Exercise and Education to avert Vascular Events after Non-disabling stroke and Transient ischemic attack (PREVENT) Trial is to determine whether the timely delivery of secondary…
- Trial name
- PREVENT (NCT00885456)
- Testing
- PREVENT program, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Marilyn MacKay-Lyons
Ischemic Stroke, Intracranial Arteriosclerosis
Pair Antiplatelet THerapy in Ischemic Stroke With Intracranial Artery Stenosis
The goal of this clinical trial is to learn about efficacy and safety of dual antiplatelet therapy in ischemic stroke with intracranial artery stenosis.
- Conditions
- Ischemic Stroke, Intracranial Arteriosclerosis, Secondary Prevention, Antiplatelet Drug
- Trial name
- PATH-ICAS (NCT06243133)
- Testing
- clopidogrel for 90 days combined with aspirin for 90 days, clopidogrel for 30 days combined with aspirin for 90 days
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Sichuan Provincial People's Hospital
To Investigate the Relationship Between the Adherence of HHEP After ISTIA and Stroke Recurrence or Cardiovascular Events.
A Nested Case-control Study on the Secondary Prevention of Ischemic Stroke and TIA by Hypertension Health Education Protocol (HHEP): The Post-Stroke Preventive Trial
Patients with a diagnosis of ischemic stroke or TIA (ISTIA), who are treated at hospital are asked to participate in our pre specified hypertension health education protocol (HHEP) after discharge from our hospital.HHEP was used…
- Trial name
- NCT01812421
- Testing
- Hypertension Health Education Protocol (HHEP)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Acute Ischemic Stroke
An Application Provides Personalized Suggestions Based on Secondary Prevention Risk Factors to Stroke Patients
This study applied an application that provides personalized suggestions and explore the effect of this actual intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07098143
- Testing
- Risk factor management
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China
Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention…
- Trial name
- SINEMA (NCT03185858)
- Testing
- SINEMA intervention
- Where
- China
- Volunteers
- 1,299 people
- Sponsor
- Duke Kunshan University
Stroke
The Effects of tDCS Combined With rTMS on Post-stroke Cognitive Impairment
If there is a comparison group: Researchers will compare [insert groups] to see if [insert effects] The purpose of the clinical trial is to find a treatment for stroke patients with cognitive impairment, and the main questions it…
- Trial name
- NCT06252987
- Testing
- routine treatment, Non-invasive brain stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University