Clinical trials: Sedation, Conscious
Moderate Sedation, Colonoscopy
GABA Antagonist to Improve Reversal of Anesthesia With High-density EEG Surveillance
For recent years, patients are more likely to accept sedation during endoscopic examination due to better quality and experience.
- Trial name
- NCT04329585
- Testing
- flumazenil
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
BPH (Benign Prostatic Hyperplasia), BPH
INTUPRO in the Treatment of Benign Prostatic Hyperplasia-Related Symptoms
The goal of this clinical trial is to determine whether INTUPRO can improve the quality of life in patients with Benign Prostate Hyperplasia (BPH).
- Conditions
- BPH (Benign Prostatic Hyperplasia), BPH, BPH With Other Lower Urinary Tract Symptoms
- Trial name
- NCT07381127
- Testing
- INTUPRO ionic fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- inTumo Therapeutics, Inc.
Airway Management
I-scoop vs. C-Mac D-Blade Videolaryngoscope for Airway Management Under Spontaneous Breathing and Analgosedation
The purpose of this clinical trial is to investigate whether the videolaryngoscope i-scoop makes airway management under spontaneous breathing and analgosedation more clinically practicable than the established standard device…
- Trial name
- OWN BREATH 2 (NCT07624162)
- Testing
- Airway management under spontaneous breathing with the i-scoop videolaryngoscope, Airway management under spontaneous breathing with the C-Mac D-Blade videolaryngoscope
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Hannover Medical School
Conscious Sedation
Dexmedetomidine for Continuous Sedation
The study aims to demonstrate that dexmedetomidine is non-inferior to current best practice sedation with propofol/midazolam and daily sedation stops, in maintaining a target depth of sedation in long-stay intensive care unit…
- Trial name
- NCT00226785
- Testing
- Dexmedetomidine
- Where
- 4 sites in Finland, Switzerland
- Volunteers
- 900 people
- Sponsor
- Orion Corporation, Orion Pharma
Anti-anxiety Agents, Moderate Sedation
Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment
The aim of this study is to assess the efficacy of Dexmedetomidine drug either used sublingually or intranasally in managing healthy children during dental treatment
- Trial name
- NCT04237532
- Testing
- Intranasal Dexmedetomidine, Sublingual Dexmedetomidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Nourhan M.Aly
Conscious Sedation Failure During Procedure
Oral Midazolam for Sedation in Esophagogastroduodenoscopy(EGD)
Can oral midazolam used for sedation in patients undergoing upper gastrointestinal endoscopy ?
- Trial name
- NCT01990937
- Testing
- Oral midazolam
- Where
- Thailand
- Volunteers
- 260 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Virtual Reality Therapy, Fertilization in Vitro
Effectiveness of Hypnosis Via Virtual Reality During Oocyte Retrieval
This study compares hypnosis via virtual reality to sedation with commonly used intravenous anesthetic agents (propofol and remifentanil) during oocyte retrieval.
- Conditions
- Virtual Reality Therapy, Fertilization in Vitro, Propofol, Remifentanil
- Trial name
- NCT05244538
- Testing
- Virtual reality distraction, Propofol-remifentanil sedation
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Conscious Sedation Failure During Procedure
Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a lengthy and uncomfortable procedure that requires adequate sedation. Propofol is the commonly used sedative during ERCP.
- Trial name
- NCT04997967
- Testing
- Ketamine/Propofol, Propofol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Vasectomy, Sedation
Comparison of Intravenous V/S Nasal Atomizer Delivery of Midazolam for Conscious Sedation for No-scalpel Vasectomy
Purpose: This study compared administration of midazolam via intravenous route with nasal atomizer route for moderate sedation in an office-based vasectomy clinic.
- Trial name
- NCT06449365
- Testing
- midazolam by nasal atomizer, intravenous midazolam
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Paroxysmal Atrial Fibrillation
Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation
This prospective, multicenter, randomized, controlled, noninferiority trial will compare local anesthesia with conscious sedation and general anesthesia in patients undergoing pulsed field ablation for paroxysmal atrial…
- Trial name
- PULSE-SED (NCT07877519)
- Testing
- Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System
- Where
- China
- Volunteers
- 390 people
- Sponsor
- China National Center for Cardiovascular Diseases
Carbon Dioxide
Non Invasive End Tidal Carbon Dioxide Monitoring During Moderate Sedation
CO2 monitoring through non-invasive methods at different O2 flow rates may provide an early warning sign of hypoventilation during procedural sedation.
- Trial name
- EtCO2 (NCT04588272)
- Testing
- DualGuard
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Tachycardia, Ventricular
Bispectral Index Monitoring During Testing in the Electrophysiology Lab
BACKGROUND Physician-guided moderate sedation, administered by a Registered Nurse has been the standard of practice for patients undergoing a wide range of electrophysiology procedures during the past decade.
- Trial name
- NCT00749671
- Testing
- Bispectral index monitoring, Ramsey Sedation Scale
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baystate Medical Center
Gastrointestinal Endoscopy
Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research
The purpose of this study is mainly about the feasibility and rationality of moderate sedation combined with acupuncture anesthesia in the application of gastroscopy and colonoscopy ,Then we evaluate the effectiveness and…
- Trial name
- NCT05485064
- Testing
- fentanyl, eletroacupuncture(transcutaneous electrical acupuncture point stimulation ), remimazolam
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Procedural Sedation, Regional Anesthesia Block
Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery
How does Lusedra compare with current standard of care (midazolam) for minimal to moderate sedation for regional anesthesia blocks prior to orthopedic surgery?
- Conditions
- Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
- Trial name
- NCT01195103
- Testing
- Fospropofol disodium, Fentanyl
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Severe Aortic Valve Stenosis, Anxiety
Virtual Reality Assisted Conscious Sedation During TAVI
Transcatheter aortic valve implantation (TAVI) is an established therapy for patients with severe aortic valve stenosis. Pain and anxiety are major contributors to procedural complications.
- Conditions
- Severe Aortic Valve Stenosis, Anxiety, Pain
- Trial name
- TAVI_VR (NCT04259723)
- Testing
- VR during TAVI
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Consciousness Disorders, Communication
Analysis of Vital, Facial and Muscular Responses Front to Music or Message in Coma, Vegetative State or Sedated Patients
Objectives: (1) To check music or voice message influence on vital signs, facial expressions or muscular tonus of coma, vegetative or sedated patients; (2) To connect the existence of patient's responsiveness with the Glasgow…
- Conditions
- Consciousness Disorders, Communication, Intensive Care
- Trial name
- NCT01141790
- Testing
- Music and voice message
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Stroke, Brain Ischemia
Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
Dexmedetomidine is a unique sedative medication able to provide sedation without causing respiratory depression and maintaining neurological functions.
- Conditions
- Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
- Trial name
- NCT01845441
- Testing
- Dexmedetomidine, Fentanyl, Midazolam
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University Hospitals Cleveland Medical Center
Moderate Sedation, Laceration
Comparison of N2O Inhalation and Ketamine in Pediatric PSA
Ketamine provides effective and relatively safe sedation analgesia for primary closure of lacerated pediatric patients However, deep sedation and adverse effects suggest the opportunity to develop alternative strategies We…
- Trial name
- PSA (NCT00834730)
- Testing
- N2O gas vs ketamine
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Conscious Sedation, Procedural Sedation
Propofol vs Remifentanil for Sedation in Gastroscopy
This prospective randomized study aims to compare propofol and remifentanil for sedation during elective diagnostic gastroscopy.
- Trial name
- ROPOGAST (NCT07336628)
- Testing
- Propofol (Astra-Zeneca), Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital