Clinical trials: Sedation Complication
Sedation Complication, Mechanical Ventilation in Neonates
Pharmacokinetics-pharmacodynamics of Morphine With or Without Midazolam Administered by Continuous Infusion in Neonatal Intensive Care
This study aims to describe a dose-effect relationship of morphine alone and morphine and midazolam administered as continuous infusion in neonates hospitalized in Neonatal intensive care unit and undergoing mechanical…
- Trial name
- NCT05371886
- Testing
- Dose-effect relationship of morphine +/- midazolam administration
- Where
- 5 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Dental Anxiety, Sedation Complication
Remimazolam in the Extraction of Impacted Wisdom Teeth
Benzodiazepines, represented by midazolam, are often used for sedation in outpatient surgery in dentistry. However, midazolam has the problems of slow consciousness recovery and long recovery time, which brings trouble to the…
- Conditions
- Dental Anxiety, Sedation Complication, Anterograde Amnesia
- Trial name
- NCT05350085
- Testing
- Remimazolam besylate, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Complications
Thiopental Versus Propofol During Magnetic Resonance Imagining in Children: Something Old, Something New
Magnetic resonance imagining (MRI) in children requires sedation to achieve the degree of cooperation or immobilization, necessary to complete these procedures successfully.
- Trial name
- NCT01318044
- Testing
- Propofol and Thiopental
- Where
- Albania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Clinical Centre of Kosova
Anesthesia for Urologic Endoscopic Surgery, Urinary Calculi
Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy
This single-center single-blind randomized trial compares fospropofol disodium and propofol for anesthesia in elective ureteroscopy patients.
- Trial name
- NCT07659132
- Testing
- Fospropofol disodium plus sufentanil for anesthesia induction, Propofol plus sufentanil for anesthesia induction
- Volunteers
- 190 people
- Sponsor
- Shiyou Wei
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau
Percutaneous Endoscopic Gastrostomy, Enteral Nutrition Feeding
Comparison of Sedated and Unsedated PEG in Elderly ASA IV Patients
This prospective observational cohort study aims to compare the safety and clinical outcomes of sedated and unsedated percutaneous endoscopic gastrostomy procedures in elderly patients classified as ASA IV.
- Conditions
- Percutaneous Endoscopic Gastrostomy, Enteral Nutrition Feeding, Dysphagia, Elderly Patients (>65 Years)
- Trial name
- NCT07758153
- Volunteers
- 70 people
- Sponsor
- Mersin University
Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
This study aims to compare the safety and efficacy of remimazolam and propofol in EUS-FNA/FNB sedation. This study is a prospective, single-blind study.
- Conditions
- Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication, Remimazolam
- Trial name
- NCT05437497
- Testing
- Remimazolam Injection, Propofol Injection
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Pain, Postoperative
Innovative Approaches to Assessment of Pain Control and Sedation in the NICU
It is difficult to assess pain and agitation in the NICU population because for a multitude of reasons including the pre-verbal nature of the patient population, the atypical pain response of premature infants, and the use of…
- Trial name
- NCT03057782
- Testing
- Waveguard (TM) EEG cap, Micro Movement Sensor, Pico Movement Sensor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Sedation Complication, Covid19
EEG-based Sedation Protocol for Patients on Mechanical Ventilation Due to SARS-CoV-2 Pneumonia
Deep sedation in patients with COVID-19 may be challenging in many aspects. The use of an EEG-based protocol to guide deep sedation may be useful in this particular population, considering their unusually high sedation…
- Trial name
- NCT04699916
- Testing
- EEG based protocol for deep sedation
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- University of Chile
Pain, Chronic
Impact of Sedation on Patient Satisfaction, Radiation Exposure, and Complications in Lumbar Transforaminal Epidural Steroid Injections: A Retrospective Cohort Study
Radicular low back pain due to disc herniation is frequently observed. There are rest, medical treatments, physical medicine modalities, interventional procedures for pain and surgical options in the treatment of lumbar disc…
- Trial name
- NCT06539390
- Testing
- Transforaminal Epidural Injections?
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Sedation and Analgesia, Pain Intensity Assessment
Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units
Introduction: Pain is a subjective symptom, a physiological response that is difficult to assess, which affects the body physically and/or emotionally.
- Conditions
- Sedation and Analgesia, Pain Intensity Assessment, Mechanical Ventilation Complication
- Trial name
- PainICU (NCT07182851)
- Where
- 4 sites in Brazil
- Volunteers
- 370 people
- Sponsor
- Centro Universitário Augusto Motta
Mechanical Ventilation Complication
Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding Study
Critically ill infants and children who are mechanically ventilated are often given large doses of opiates and benzodiazepines to provide analgesia-sedation.
- Trial name
- NCT02249039
- Testing
- intermittent IV CLON
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Johns Hopkins University
Sedation Complication, Endoscopic Ultrasonography
Propofol Infusion-Based Sedation on Anesthesia-Related Adverse Events in Endoscopic Ultrasonography
Endoscopic ultrasonography (EUS) is an endoscopic procedure performed to investigate conditions affecting the stomach, liver, and bile ducts, as well as for therapeutic interventions.
- Conditions
- Sedation Complication, Endoscopic Ultrasonography, Procedural Sedation
- Trial name
- NCT06389045
- Testing
- Procedural Sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Samsun University
Aortic Stenosis, Sedation Complication
High Flow Nasal Oxygen Cannula in Transcatheter Aortic Valve Replacement: Complications and Biomarkers
Background Transcatheter aortic valve replacement is a risky procedure, performed in patients that can also be considered at risk of developing complications.
- Trial name
- HIGH-OXY-TAVR (NCT05958537)
- Testing
- High flow nasal oxygen
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Hospital Clinic of Barcelona
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Analgesia, Ketamine Toxicity
Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)
This study, prospectively evaluate the efficacy and safety of ketamine administered in continuous infusion lasted more than 12 hours in children admitted to Pediatric Intensive Care Unit of Padova.
- Conditions
- Analgesia, Ketamine Toxicity, Bronchospasm, Sedation Complication
- Trial name
- KISS (NCT04427605)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Azienda Ospedaliera di Padova
Opioid Use, Unspecified, Remifentanil
Anesthesia for Vascular Access Devices
Our aim was to investigate whether remifentanil use in both infusion and bolus techniques could provide sufficient sedation and analgesia without serious adverse effects for central venous access device procedures under monitored…
- Conditions
- Opioid Use, Unspecified, Remifentanil, Sedation Complication, Analgesia
- Trial name
- NCT04749069
- Testing
- Comparison of pain intensity rating scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event
TEAS for Sedation During ERCP: A Multicenter Trial With Mechanistic Substudy
1. The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS), a non-invasive therapy that applies mild electrical current to specific points on the skin, can help patients undergoing…
- Conditions
- Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event, Procedural Pain, Sedation-related Complications
- Trial name
- TEAS-ERCP-MC (NCT07440342)
- Testing
- TEAS + Conscious Sedation
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Beijing 302 Hospital
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital