Clinical trials: Sedation or Anesthesia
Sedation or Anesthesia
A Phase III Study Evaluating The Efficacy and Safety of HSK3486 for Sedation or Anesthesia
This is a Phase III, randomized, double-blind, propofol-controlled, parallel-design, multi-center study to evaluate the efficacy and safety of HSK3486 for sedation or anesthesia in patients undergoing colonoscopy and gastroscopy.
- Trial name
- NCT03674008
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Sedation and Anesthesia for Adult Colonoscopy Procedures
A Study Evaluating the Efficacy and Safety of HSK3486
A double-blind, randomized, active controlled, multi-center, parallel group study comparing HSK3486 with Propofol, in patients undergoing a colonoscopy.
- Trial name
- NCT03709056
- Testing
- HSK3486, Propofol
- Where
- 8 sites in China
- Volunteers
- 94 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Sedation, Spinal Anesthesia
Sedation Using Virtual Reality During Surgery Under Spinal Anesthesia
During spinal anesthesia, sedation is performed using intravenous sedative for the patient's comfort and appropriate surgical environment.
- Trial name
- NCT03055663
- Testing
- Sedation by watching virtual reality sedative program, Sedation by using intravenous sedative, Midazolam
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Seoul National University Hospital
Sedation, Anesthesia, Spinal
Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia
This study is to investigate on the objective relevance between bispectral index (BIS) and Observer's assessment of alertness/sedation (OAA/S) scale in patients sedated with Midazolam, propofol and dexmedetomidine during spinal…
- Trial name
- BIS (NCT03399019)
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Hallym University Medical Center
Conscious Sedation Failure During Procedure, Analgesia
Lidocaine as Local Anesthetics in Children Under Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department in laceration repair. Lidocaine is the local anesthetics widespread used. Ketamine leads to dissociative amnesia.
- Conditions
- Conscious Sedation Failure During Procedure, Analgesia, Anesthesia
- Trial name
- NCT02205502
- Testing
- Lidocaine, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Deep Sedation, Anesthesia, General
Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia
The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus
- Trial name
- N20 (NCT00717574)
- Testing
- Sevoflurane group, Propofol group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Oklahoma
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Inguinal Hernia, Anesthesia, Local
A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty
The aim of this RCT is to compare patient outcomes of inguinal hernioplasty under Local Anaesthesia alone versus Local Anaesthesia and Conscious Sedation Specific study objectives are to determine the effect of conscious sedation…
- Conditions
- Inguinal Hernia, Anesthesia, Local, Conscious Sedation
- Trial name
- NCT02444260
- Testing
- Midazolam, Intravenous Normal Saline, Bupivocaine
- Where
- Jamaica
- Volunteers
- 180 people
- Sponsor
- The University of The West Indies
Conscious Sedation Under Spinal Anesthesia
The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl
Since intrathecal fentanyl is known to sedation effect, intrathecal fentanyl will result in lowering propofol requirement for conscious sedation under spinal anesthesia.
- Trial name
- NCT01232270
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Procedural Sedation, Regional Anesthesia Block
Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery
How does Lusedra compare with current standard of care (midazolam) for minimal to moderate sedation for regional anesthesia blocks prior to orthopedic surgery?
- Conditions
- Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
- Trial name
- NCT01195103
- Testing
- Fospropofol disodium, Fentanyl
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Conscious Sedation, Remifentanil
Local Anaesthesia and Remifentanil Sedation Versus Total Intravenous Anaesthesia for Hysteroscopic Surgery in an Ambulatory Surgery Department.
The purpose of this study is to compare a new method: the combination of conscious sedation with remifentanil (a shortlasting opioid drug) and local anaesthesia, with the traditional general anaesthesia for hysteroscopic surgery.
- Conditions
- Conscious Sedation, Remifentanil, Hysteroscopic Surgery, Anesthesia Recovery Period
- Trial name
- NCT00763789
- Testing
- local anaesthesia and remifentanil sedation, total intravenous anaesthesia
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Copenhagen University Hospital at Herlev