Clinical trials: Sedative, open to volunteers
Sleep Disorders
Optimization of Melatonin Administration in Healthy Adults
The goal of this clinical trial is to evaluate whether the timing and dosage of exogenous melatonin can improve sleep onset and maintenance in healthy adults aged 18-45 years (50% female) with no history of sleep disorders.
- Trial name
- MelOpt (NCT07514507)
- Testing
- Mel 2 mg 30 min, Mel 2 mg 3 h, Mel 4 mg 30 min
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Controlled Hypotension for Nasal Surgeries
Comparison of Two Sedative Agents in Terms of Controlled Hypotension
Propofol and Isoflurane are commonly used sedative agents in general anaesthesia.Both these drugs have a side effect of decreasing blood pressure which when used optimally can be used to acheive controlled hypotention.
- Trial name
- NCT07460050
- Testing
- Propofol, Isoflurane
- Where
- Pakistan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Sedation
a Prospective Randomised Study Evaluating the Efficacy of Intranasal Midazolam and Dexmedetomidine as a Sedative Agent in Management of Mandible Fracture
COMPARISON OF THE EFFICACY OF INTRANASAL MIDAZOLAM AND DEXMEDETOMIDINE AS A SEDATIVE AGENT IN SURGICAL MANAGEMENT OF ISOLATED MANDIBLE FRACTURE- conducted on 32 subject to assess depth of sedation by using OAA/S and assess effect…
- Trial name
- NCT07502651
- Testing
- Midazolam (Intranasal), Dexmedetomidine (Intranasal)
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pregnant Women, Psychotropic Drugs
National Pregnancy Registry for Psychiatric Medications
The National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications such as antidepressants, ADHD medications, sedative hypnotics, and atypical antipsychotics that many…
- Trial name
- NCT01246765
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anesthesia
Oral Dexmedetomidine in Pediatric MRI
The objective of this preliminary study is to assess the utility of oral dexmedetomidine as the sole sedative agent in pediatric population undergoing MRI.
- Trial name
- NCT05619627
- Testing
- Dexmedetomidine, General Anesthesia (control group)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soroush Merchant
Ketamine Adverse Reaction
Evaluation of Ketamine as Sedative Agent in Endoscopic Retrograde Cholangiopancreatography (ERCP)
This is a study evaluating the usage of Ketamine as sedative agent in ERCP. The usage of Ketamine will be compared to the standard sedation in our center, which is Midazolam in combination with Pethidine as analgesia.
- Trial name
- NCT04490031
- Testing
- Ketamine Hydrochloride
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre