Clinical trials: Segmentectomy, open to volunteers
Liver Cancer, Adult
RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study
Radiation segmentectomy (RS) refers to selective infusion of Y-90 microspheres to the tumor bearing hepatic segment of hepatic artery. Majority of the data on RS is based on the Glass microspheres experience.
- Trial name
- RASEREM (NCT07345247)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara University
Non Small Cell Lung Cancer
3-Dimensional Virtual Reality Modelling With Intravascular Indocyanine Green Fluorescence Mapping for Targeted Pulmonary Segmental Resection Trial
With the advent of CT screening for lung cancer, an increasing number of NSCLCs are being detected at very early stages, and the demand for pulmonary segmentectomy is rising rapidly.
- Trial name
- NCT06638125
- Testing
- 3-Dimensional VR Modelling (Elucis) with Intravascular Indocyanine Green Fluorescence Mapping, 3-Dimensional Modelling (Synapse 3D) with Intravascular Indocyanine Green Fluorescence Mapping
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Segmentectomy, Lung Adenocarcinoma
Segmentectomy for Ground Glass-dominant Invasive Lung Cancer (ECTOP-1012)
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1012. The goal of this clinical trial is to confirm the theraputic effect of segmentectomy for ground glass-dominant invasive…
- Trial name
- NCT05717803
- Testing
- Segmentectomy
- Where
- China
- Volunteers
- 307 people
- Sponsor
- Fudan University
Lung Neoplasms, Surgery
Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field
This study aims to investigate whether segmentectomy had non-inferiority long-term oncological effects (disease-free survival and overall survival) compared with lobectomy in the treatment of patients with early-stage non-small…
- Trial name
- NCT04944563
- Testing
- Segmentectomy, Lobectomy
- Where
- China
- Volunteers
- 1,120 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Breast Neoplasms, Mastectomy, Segmental
Acellular Dermal Matrix(SureDerm BCS) in Breast-Conserving Surgery for Breast Cancer Patients
The goal of this clinical trial is to evaluate whether the use of an acellular dermal matrix (SureDerm) can improve cosmetic satisfaction and is safe in women with breast cancer undergoing breast-conserving surgery.
- Trial name
- NCT07345026
- Testing
- Acellular Dermal Matrix (SureDerm BCS), Standard Breast-Conserving Surgery
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Seoul St. Mary's Hospital
Breast Cancer, DCIS
Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of treatment and can be…
- Conditions
- Breast Cancer, DCIS, LCIS
- Trial name
- MAPBI (NCT03936478)
- Testing
- MRIdian Radiation Treatment Unit
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Hemophagocytic Lymphohistiocytosis, Epstein-Barr Virus
Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement
EBV-HLH is a rare disease with high mortality, especially for those with intestinal involvement. In order to reduce disease burden and improve survival of these patients, we conduct a prospective observational study to explore…
- Conditions
- Hemophagocytic Lymphohistiocytosis, Epstein-Barr Virus, Bowel Resection
- Trial name
- NCT06131489
- Testing
- Segmental bowel resection combined with the DEP regimen
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Non-Small Cell Lung Cancer
Septum-guided Segmentectomy for 2-3 cm Clinical Stage IA3 Peripheral Non-Small Cell Lung Cancer
This is a single-center, prospective, single-arm, open-label clinical trial evaluating the efficacy and safety of septum-guided segmentectomy in patients with 2-3 cm clinical stage IA3 peripheral non-small cell lung cancer…
- Trial name
- SGS2606 (NCT07780591)
- Testing
- septum-guided anatomical segmentectomy
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
Yttrium-90 Radiation Segmentectomy for Hepatocellular Carcinoma
This is a prospective, single-blinded, single-arm, open-label Phase II trial of trans-arterial radiation segmentectomy using Yttrium-90 glass microspheres (TheraSphere®) for Hepatocellular Carcinoma (HCC) participants with…
- Conditions
- Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatocellular Carcinoma Non-resectable
- Trial name
- NCT07110233
- Testing
- TheraSphere® Yttrium-90 microspheres, Health Related Quality of Life Questionnaires (HRQOL)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, San Francisco
Lung Neoplasm, Pulmonary Metastasis
HSI for Intersegmental Plane Identification During Sublobar Pulmonary Resections
The purpose of this study is the identification of the intersegmental plane and navigation during sublobar pulmonary resections in lung cancer using Hyperspectral Imaging, the comparison with ICG fluorescence intersegmental plane…
- Trial name
- HYPER-Seg (NCT05676788)
- Testing
- Hyperspectral Imaging
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- LungenClinic Grosshansdorf
Lung Adenocarcinoma
Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
This study aims to evaluate the superiority in recurrence-free survival of lobectomy compared with segmentectomy in patients with lung adenocarcinoma ≤ 2 cm with micropapillary and solid subtype positive by intraoperative frozen…
- Trial name
- NCT05838053
- Testing
- Lobectomy with systemic lymph node dissection, Segmentectomy with systemic lymph node dissection
- Where
- China
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Lung Cancer, Non-Small Cell Lung Cancer
Is 3D Modeling From Non-contrast CT Accurate for Minimally Invasive Lung Segmentectomies ?
To assess the RELIABILITY in terms of accuracy of 3D-CT and 2D-CT reconstructions compared to intraoperative data regarding bronchovascular anatomy and tumor location.
- Trial name
- 3D-LS (NCT07234604)
- Testing
- Thoraco-abdomino-pelvic CT scan without and with contrast injection.
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Thoracic Surgery, Pneumonectomy
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Conditions
- Thoracic Surgery, Pneumonectomy, Lobectomy, Segmentectomy
- Trial name
- NCT05525923
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- OpalGenix, Inc
Non-small Cell Lung Cancer
Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer
Lungs are made up of individual lobes. When a lung cancer tumour is detected in one of these lobes, surgeons typically perform a Lobectomy.
- Trial name
- NCT02570815
- Testing
- indocyanine green
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch, Local Incision, Postoperative Pain
- Trial name
- NCT07591220
- Testing
- Loxoprofen Sodium Patch on the incision site, Loxoprofen Sodium Patch on the contralateral side
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Lung Surgery, Enhanced Recovery After Surgery, ERAS
Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery
This study aims to evaluate the clinical effectiveness of the Enhanced Recovery After Surgery (ERAS) program for pediatric lung surgery at our institution.
- Conditions
- Lung Surgery, Enhanced Recovery After Surgery, ERAS, Pediatric
- Trial name
- NCT07241286
- Testing
- Enhanced Recovery After Surgery, ERAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax, Pleural Effusion
16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy
The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or…
- Trial name
- ChestDrain (NCT06958848)
- Testing
- 16 F chest tube, 24 F chest tube, Early removal
- Where
- Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Basel, Switzerland
Deep Endometriosis
Patients Undergoing Total Intracorporeal or Extracorporeal Anastomosis After Segmental Resection for Deep Endometriosis
Impact on the quality of life (in terms of functional recovery and gastrointestinal symptoms) of segmental resection surgery in patients with intestinal endometriosis undergoing either a totally intracorporeal or extracorporeal…
- Trial name
- NCT06826378
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University