Clinical trials: Selective Estrogen Receptor Modulator, open to volunteers
Endometriosis
Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial dysfunction in women with endometriosis. Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin will…
- Trial name
- Endo2/SA3 (NCT05059626)
- Testing
- simvastatin 10mg, Bazedoxifene 20/Estrogens,Con 0.45Mg Tb
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Penn State University
Oligoasthenoteratozoospermia, Male Infertility
Comparative Efficacy of Antioxidants Alone Versus Combined Therapy With SERMs or FSH in Normogonadotropic Idiopathic OAT Patients: A Randomized Controlled Trial
This prospective randomized controlled trial will compare three treatment approaches for men with idiopathic oligoasthenoteratozoospermia (OAT), a condition characterized by abnormalities in sperm count, movement, and shape…
- Trial name
- NCT07862725
- Testing
- Antioxidants + Clomiphene Citrate, Antioxidants + FSH, Antioxidants Alone
- Where
- Qatar
- Volunteers
- 360 people
- Sponsor
- Hamad Medical Corporation
Schizophrenia, Schizophreniform Disorders
Bazedoxifene -Treatment for Women With Schizophrenia
To study the effect of adjunctive bazedoxifene - a selective estrogen receptor modulator (SERM) in a double blind, placebo-controlled adjunctive study in the treatment of women with schizophrenia.
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizo Affective Disorder
- Trial name
- NCT04113993
- Testing
- Bazedoxifene Acetate
- Where
- Australia
- Volunteers
- 160 people
- Sponsor
- The Alfred