Clinical trials: Selenium
Selenium Status, Selenium Uptake From Fish and Shellfish
Selenium Status Measured in Blood After a Higher Intake of Fish and Shellfish - a Randomized Dietary Intervention Study
The primary aim of this study is to investigate, whether higher intake of selenium rich food items such as fish and shellfish, is associated with higher selenium blood levels.
- Trial name
- NCT01224249
- Testing
- Fish and shellfish
- Where
- Denmark
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Nutritional Requirements
Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels
In this study, we will evaluate the effectiveness of several doses of oral selenomethionine in raising biomarkers of selenium status including plasma selenium concentrations.
- Trial name
- LoDoSe (NCT00803699)
- Testing
- selenium as L-selenomethionine
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Type 2 Diabetes Mellitus
Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus
Null hypothesis: No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).
- Trial name
- Vit C (NCT01319734)
- Testing
- Vitamin C, glyburide
- Where
- Sudan
- Volunteers
- 50 people
- Sponsor
- Al-Neelain University
Osteoporosis
Selenium for Musculoskeletal Health
This research aims to determine whether selenium supplements improve bone and muscle health in older women at risk of osteoporosis (low bone density or weak bones) and fracture (broken bones).
- Trial name
- NCT02832648
- Testing
- selenase (selenium)
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
n-3 Polyunsaturated Fatty Acids, Selenium
Enriched QUARTET® Hen Eggs and Cardiovascular Function
Role of oxidative stress in the development of cardiovascular diseases is well known and extensively investigated, because of its direct effects on vascular function, but also on the activation of the immune response.
- Conditions
- n-3 Polyunsaturated Fatty Acids, Selenium, Vitamin E, Lutein
- Trial name
- NCT04564690
- Testing
- QUARTET® hen eggs (enriched in n-3 PUFA, selenium, vitamin E and lutein), Regular hen eggs
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Chagas Disease
Selenium Treatment and Chagasic Cardiopathy (STCC)
Background: Chagasic myocardiopathy caused by the protozoa Trypanosoma cruzi has been the principal cause of cardiac death in Latin America.
- Trial name
- STCC (NCT00875173)
- Testing
- Selenium
- Where
- Brazil
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Inflammation, Malnutrition
Effect of Selenium Supplementation on Inflammatory,Oxidative and Nutritional Markers in Hemodialysis Patients
The aim of this study is to evaluate the effect of selenium supplementation on oxidative, inflammatory and nutritional markers in hemodialysis patients.
- Conditions
- Inflammation, Malnutrition, Complication of Hemodialysis
- Trial name
- NCT01147354
- Testing
- selenium yeast
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Zahra Sohrabi
Precancerous/Nonmalignant Condition, Prostate Cancer
Vitamin E, Selenium, and Soy Protein in Preventing Cancer in Patients With High-Grade Prostate Neoplasia
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development or recurrence of cancer. Vitamin E, selenium, and soy protein may be effective in preventing the development of prostate…
- Trial name
- NCT00064194
- Testing
- selenium, soy protein isolate, vitamin E
- Where
- 3 sites in Canada
- Volunteers
- 310 people
- Sponsor
- NCIC Clinical Trials Group
Healthy
Relatively Healthy Male Veterans Observed Over Time to See What Types of Diseases Develop
The purpose of this study is to gather a mixed racial group of relatively healthy male Veterans (for example, White, African-American, and Hispanic), who are at least 50 years of age.
- Trial name
- ACTIVE Health (NCT00076141)
- Where
- 9 sites in United States
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Liver Disease
Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis
Non-alcoholic steatohepatitis represents 10 - 15% total cases of hepatic cirrhosis. In the upcoming years, the economic burden of this disease will increase and will mean an important problem for our health system due to obesity…
- Trial name
- NCT01650181
- Testing
- Metformin, Siliphos+ Selenium - Methionine + Alpha Lipoic Acid
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Generalized Epileptic
Study on Serum Zinc and Selenium Levels in Epileptic Patients
This study was carried out with the purpose of evaluating zinc and selenium levels in serum of epileptic patients and compare with normal individuals.
- Trial name
- NCT01764516
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Ulcerative Colitis (UC)
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Micronutrient deficiencies are common in ulcerative colitis (UC). Selenium deficiency is associated with worse disease outcomes including disease flares and need for surgery.
- Trial name
- Selenium-UC (NCT07427017)
- Testing
- Selenium supplementation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Northwestern University
Ventricular Dysfunction, Left
High-dose Selenium Supplementation in Patients With Left Ventricular Assist
This planned pilot study is a monocentric, prospective, double-blind randomized and placebo controlled clinical study. The SOS-LVAD Trial can be assigned to the clinical Phase III.
- Trial name
- SOS-LVAD (NCT02530788)
- Testing
- Selenium Supplement (sodium selenite)
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- RWTH Aachen University
Graves' Disease
Treatment of Graves' Hyperthyroidism With Selenium Plus Methimazole
Evaluation of the efficacy of the combined treatment (methimazole plus selenium) in the control of hyperthyroidism as compared to methimazole alone in 30 Graves' disease (GD) untreated patients.
- Trial name
- NCT02727738
- Testing
- Selenium, Methimazole
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pisa
Depression - Major Depressive Disorder
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
The purpose of this study is to investigate the role and mechanisms of selenium in depression among children and adolescents, aiming to provide new insights for understanding the pathogenesis and treatment of depression in this…
- Trial name
- NCT07203144
- Testing
- selenium yeast supplementation
- Where
- China
- Volunteers
- 172 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Dandruff
Effects on the Scalp Lipids and TEWL of a 1% Selenium Disulfide and 1% Salicylic Acid Antidandruff Shampoo on Dandruff Scalp
The aim of this study was to investigate the changes in the scalp lipids and TEWL in dandruff subjects treated by 1% Selenium Disulfide (SeS2)/1% salicylic acid-based shampoo after an antidandruff treatment and after a remanence…
- Trial name
- NCT05503706
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Oxidative Stress, Inflammation
Effect of Selenium on Serum Adiponectin, Homocystein and Malnutrition-inflammation Complex Syndrome in Hemodialysis Patients
The aim of this study is to determine the effect of selenium supplementation as an antioxidant on serum adiponectin, HSCRP , ferritin , transferrin, albumin and homocysteine level.
- Conditions
- Oxidative Stress, Inflammation, Malnutrition
- Trial name
- NCT01150786
- Testing
- Selenium Supplement
- Where
- 2 sites in Iran
- Volunteers
- 80 people
- Sponsor
- maryam ekramzadeh
Type 2 Diabetes
Effects of Selenium Towards Type 2 Diabetes
According to the prevalence of non-communicable chronic diseases and aging population characteristics, this study is exploring the coexist effects combined with various dimensions: nutritional functions, metabolic homeostasis…
- Trial name
- NCT06457984
- Testing
- Selenium nutritional supplementation
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cardiac Arrest
Selenium to Improve Neurological Outcome After Cardiac Arrest
After cardiac arrest and successful resuscitation it can happen that the brain function of a patient is impaired because the brain was without oxygen for a prolonged period of time.
- Trial name
- SCPR (NCT01390506)
- Testing
- Sodium-selenite
- Where
- Austria
- Sponsor
- Medical University of Graz
Selenium Deficiency
Correction of Selenium Deficiency Has Effect on Thyroid Function
Previous literature has found potential association between selenium deficiency and inactivated glutathione peroxidase and deiodinase, which may contribute to subsequent elevation of T4 and ratio of T4/T3.
- Trial name
- NCT03445078
- Testing
- selenium supplementation, ordinary corn powder
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital