Clinical trials: Selenium, open to volunteers
Ulcerative Colitis (UC)
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Micronutrient deficiencies are common in ulcerative colitis (UC). Selenium deficiency is associated with worse disease outcomes including disease flares and need for surgery.
- Trial name
- Selenium-UC (NCT07427017)
- Testing
- Selenium supplementation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Northwestern University
Heart Failure
A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure
Heart failure is a common and serious condition. Despite rapid advancements in heart failure treatment, the prognosis remains severe.
- Trial name
- DANUTRIO-HF (NCT06694727)
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule, Selenium 100 Micrograms Oral Tablets
- Where
- Denmark
- Volunteers
- 4,044 people
- Sponsor
- Tor Biering-Sørensen
Heart Failure
The SELEQT-HF (SELEnium and CoQ10 NuTrition for Heart Failure) Study Will Evaluate the Effect of Adding Selenium/and coQ10 on Top of Standard HF Therapy in Patients With HF and Will do so Using a Pragmatic, Registry Based Randomized Controlled Trial in the Netherlands.
The goal of this clinical trial is to learn whether taking selenium and coenzyme Q10 (CoQ10) can reduce HF related events and deaths related to cardiovascular disease.
- Trial name
- SELEQT-HF (NCT07234422)
- Testing
- Selenium/CoQ10
- Where
- 7 sites in Netherlands
- Volunteers
- 1,100 people
- Sponsor
- Netherlands Heart Institute
Thyrotoxicosis
Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism
This randomized, double-blind, placebo-controlled trial evaluates the efficacy of a zinc, selenium, and L-tyrosine supplement in preventing thyrotoxicosis among adults aged 18-85 with elevated TPOAb levels and the r25191G/A SEPP1…
- Trial name
- ZEST-PREP (NCT06264544)
- Testing
- zinc, selenium, and L-tyrosine in SEPP1
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- S.LAB (SOLOWAYS)
Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain
Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis
The main rational behind intracanal medicament is to kill the bacteria inside the root canal and to avert reinfection. In absence of nutrients, the bacteria remains after obturation in root canal may not survive.
- Conditions
- Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain, Antimicrobial Effect
- Trial name
- NCT06804330
- Testing
- root canal treatment and intracanal medicament
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer
Correlation Between Selenium Levels in Human Tissues and HPV-related Cervical Lesions and Outcomes
This study investigates the relationship between selenium levels in human tissues and the persistence of HPV (human papillomavirus) infection, particularly focusing on cervical-related lesions.
- Conditions
- Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer, Persistent HPV Infection
- Trial name
- SeHPV (NCT06665841)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Thyroid Nodule
Myo-inositol and Selenium in Indeterminate Thyroid Nodules (TIR3a)
Thyroid nodules present a variable risk of malignancy depending on the cytological result obtained from the ultrasound-assisted thyroid fine needle aspiration biopsy.
- Trial name
- MYOSEL (NCT06736015)
- Testing
- Myo-Inositol 600 mg + Selenium 83 mcg
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Regina Elena Cancer Institute
Depression - Major Depressive Disorder
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
The purpose of this study is to investigate the role and mechanisms of selenium in depression among children and adolescents, aiming to provide new insights for understanding the pathogenesis and treatment of depression in this…
- Trial name
- NCT07203144
- Testing
- selenium yeast supplementation
- Where
- China
- Volunteers
- 172 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Heart Failure, Heart Failure and Reduced Ejection Fraction
Selenium Intervention Registry Randomized Trial in Heart Failure
Heart failure is a serious condition in which the heart is unable to pump blood effectively, and it remains a leading cause of hospitalization and death worldwide despite advances in treatment.
- Conditions
- Heart Failure, Heart Failure and Reduced Ejection Fraction, Heart Failure and Mildly Reduced Ejection Fraction, Heart Failure and Preserved Ejection Fraction
- Trial name
- SIRI-HF (NCT07543562)
- Testing
- Selenium Supplement
- Where
- 11 sites in Norway, Sweden
- Volunteers
- 4,326 people
- Sponsor
- Skane University Hospital