Clinical trials: Self Destructive Behavior
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Pathologic Skin Picking, Neurotic Excoriation
N-Acetyl Cysteine in Pathologic Skin Picking
The goal of the proposed study is to evaluate the comparative efficacy of N-acetyl cysteine to placebo in pathologic skin picking.
- Conditions
- Pathologic Skin Picking, Neurotic Excoriation, Psychogenic Excoriation, Dermatillomania
- Trial name
- NCT01063348
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Chicago
Suicide Risk, Suicide Attempt
Study to Refine the Effectiveness of New Generation Therapies for Suicide
The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.
- Conditions
- Suicide Risk, Suicide Attempt, Treatment Response
- Trial name
- STRENGTHENS (NCT07818889)
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Prevention of the Suicide
Short Message System (SMS) for Caregivers of Suicidal Patients to Prevent Recidivism of Suicide Attempts
Assessment of the feasibility of a monitoring device by SMS in which messages are sent by the caregiver after a suicidal act.
- Trial name
- C-SIAM (NCT03069560)
- Testing
- SMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Suicidal Behavior, Adolescent
Suicidal Behavior in Adolescents and Executive Functions
Suicide is a major public health concern, particularly among young people. In France, around 400 adolescents die by suicide every year, and suicide attempts are most frequent during adolescence.
- Trial name
- SAFE (NCT07422493)
- Testing
- Neuropsychological Tests and Psychiatric Tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Suicide Prevention, Suicide
Career Enhancement Training Study Delivered Across Career Phases
This trial tests the effectiveness of the Wingman-Connect Program delivered by USAF personnel on individual suicide risk. Randomization will be among classes at Initial Technical Training, in which 396 classes of USAF personnel…
- Trial name
- NCT05967364
- Testing
- Wingman-Connect, Stress Management
- Where
- United States
- Volunteers
- 2,970 people
- Sponsor
- University of Rochester
Suicide, Crisis; Emotional
Study About Group and Phone Follow-Up After a Crisis
Crisis stabilization centers (CSCs) provide a less costly and more comfortable alternative to Emergency Department care for individuals with suicidal crises.
- Trial name
- NCT05637203
- Testing
- THRIVE (Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement), Discharge / Safety Planning
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Rochester
Qualitative Research, Euthanasia
Requests for Euthanasia and Assisted Suicide in Establishment of Accommodation for Dependent Old Persons.
The main aim of this project is to analyze and understand the meaning of explicit requests to hasten death (euthanasia and assisted suicide) from older people living in an Establishment of accommodation for dependent old persons.
- Conditions
- Qualitative Research, Euthanasia, Assisted Suicide, Aging
- Trial name
- DESAGE (NCT03353870)
- Testing
- qualitative interview
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Suicide
Mobile Intervention for Suicidal Thoughts
One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel.
- Trial name
- NCT06593379
- Testing
- Safety planning, Treatment as usual, MIST Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Suicide, Attempted
Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients
The main objective of this study is to show MRI functional and structural differences between depressed elderly patients with a history of attempted suicide compared to depressed elderly patients with no history of attempted…
- Trial name
- SPAD-IRM (NCT03287986)
- Testing
- MRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Borderline Personality Disorder
Naltrexone in Borderline Personality Disorder
The purpose of this study is to investigate whether naltrexone reduces the intensity and duration of flashbacks and dissociative states in patients with borderline personality disorder.
- Trial name
- NCT00124839
- Testing
- Naltrexone
- Where
- 5 sites in Germany
- Volunteers
- 48 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Suicide, Attempted
Study About Treatment After a Suicide Attempt
Effective, brief, low-cost interventions for individuals who attempt suicide are needed to save lives and achieve the goals of the National Strategy for Suicide Prevention.
- Trial name
- NCT03894462
- Testing
- Attempted Suicide Short Intervention Program, Zero Suicide Usual Care
- Where
- 3 sites in United States
- Volunteers
- 443 people
- Sponsor
- University of Rochester
Autism Spectrum Disorder, Self-Injurious Behavior
Deep Brain Stimulation in Children With Autism
The purpose of this study is to evaluate the safety and possible effectiveness of deep brain stimulation (DBS) of the nucleus accumbens in children with autism spectrum disorder and treatment-refractory, repetitive self-injurious…
- Trial name
- NCT03982888
- Testing
- Deep Brain Stimulation, DBS
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- The Hospital for Sick Children
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Self Harm
Multicenter Study to Evaluate the Clinical and Cost Effectiveness of a Youth Culturally Adapted Therapy (YCMAP)
To evaluate the clinical and cost-effectiveness of a youth culturally adapted manual assisted therapy (YCMAP) in Pakistani Adolescents with a history of self-harm
- Trial name
- NCT04131179
- Testing
- Youth Culturally Adapted Manual Assisted Psychological Therapy (Y-CMAP)
- Where
- 3 sites in Pakistan
- Volunteers
- 684 people
- Sponsor
- Pakistan Institute of Living and Learning
Non Suicidal Self Injury
The Development of Psychiatric Non-Suicidal Self-Injury Risk Assessment Scale
Non-suicidal self-injury (NSSI) is a growing global mental health challenge, distinct from suicidal behavior, with unique risk factors and mechanisms.
- Trial name
- NCT06603389
- Testing
- Psychiatric Non-Suicidal Self-Injury Risk Assessment Scale
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shantou University Medical College
Suicide, Assisted, Fasting
Self-directed Dying in the Netherlands
In 2007, the frequency of so-called 'self-directed dying' in the Netherlands was investigated, that is, the voluntary cessation of eating and drinking or the taking of lethal self-collected medication.
- Conditions
- Suicide, Assisted, Fasting, Decision Making
- Trial name
- NCT06186791
- Where
- Netherlands
- Volunteers
- 37,500 people
- Sponsor
- Erasmus Medical Center