Clinical trials: Self Destructive Behavior
Interpersonal Trauma, Depression
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation.
- Conditions
- Interpersonal Trauma, Depression, PTSD, Anxiety
- Trial name
- BEAR-SI (NCT07346638)
- Testing
- BEAR-SI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Suicidal Ideation, Attempted Suicide
A Randomized Trial for Suicidal Patients
Although suicide risk is highly prevalent among the patient population in mental health care, remarkably little research exists on effective treatments. Among a small set of novel approaches, CAMS is particularly promising.
- Conditions
- Suicidal Ideation, Attempted Suicide, Suicide
- Trial name
- NCT02685943
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Vestre Viken Hospital Trust
Medication Adherence, Accidental Overdose
Blister Packaging Medication to Increase Treatment Adherence and Clinical Response
This quantitative, interview-based study will determine if increased prescription medication adherence via blister pack administration will reduce suicide related behavior among the high risk population of patients discharged…
- Conditions
- Medication Adherence, Accidental Overdose, Deliberate Overdose, Suicide, Attempted
- Trial name
- BP (NCT01118208)
- Testing
- Blister packaging medications, Dispense as usual
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- VA Eastern Colorado Health Care System
Posttraumatic Stress Disorder, Borderline Personality Disorder
Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)
Posttraumatic Stress Disorder (PTSD) with co-occurring Borderline Personality Disorder (BPD) (i.e., PTSD-BPD) is common (as high as 58%), debilitating, costly, and limited treatment options available for this population.
- Trial name
- NCT04230668
- Testing
- Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Palo Alto University
Difficulties of Emotion Regulation, Self-harm Behavior
DBT Skill Training for Autistic Adults With Difficulties in Emotion Regulation.
One in 44 has autism, 70% of them have additional mental health challenges. Currently, this patient population does not have access to effective treatment within specialist healthcare services and has struggled to benefit from…
- Conditions
- Difficulties of Emotion Regulation, Self-harm Behavior, Autism Spectrum Disorder
- Trial name
- NCT07021274
- Testing
- DBT skills training adjusted to autistic needs
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Helse Møre og Romsdal HF
Anxiety Disorder, Mood Disorder
Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.
The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.
- Trial name
- NCT00225459
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Saskatchewan
Depression
A Clinical Study of Trazodone Hydrochloride Prolonged-Release Tablets for Treatment of Depression
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of trazodone hydrochloride prolonged-release tablets for treatment of depression in Chinese population.
- Trial name
- NCT01524497
- Testing
- Trazodone
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Lee's Pharmaceutical Limited
Suicide Prevention
Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact
Suicide is a leading cause of death among adolescents in the United States and improving access to high quality just-in-time suicide interventions to reduce risk has important public health implications.
- Trial name
- NCT06499740
- Testing
- Pilot Intervention, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Bipolar Disorder, Bipolar Depression
Efficacy of Convulsive Therapies for Bipolar Depression
This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for Bipolar Disorder (BD).
- Conditions
- Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- CORRECT-BD (NCT03641300)
- Testing
- Magnetic Seizure Therapy (MST), Electroconvulsive Therapy (ECT)
- Where
- 3 sites in Canada
- Volunteers
- 76 people
- Sponsor
- Centre for Addiction and Mental Health
Suicidal Behavior
Brief Intervention and Contact Program Main Trial
Suicide is a significant public health concern and causes approximately 1.5% of all deaths in the general population in Canada. Research shows that for individuals with comorbid psychiatric illness and suicidal behaviour, the…
- Trial name
- BIC (NCT05656781)
- Testing
- Brief Intervention and Contact (BIC) based on Word Health Organization (WHO)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Suicide
Culturally Centered CBT for Latinx Youth
The primary aim of the proposed research is to test the effect of a culturally centered treatment protocol, the Socio-cognitive behavioral therapy (SCBT), versus Treatment as Usual on suicidal thoughts and attempts, and…
- Trial name
- NCT04278157
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Bradley Hospital
Nonsuicidal Self Injury, Alcohol Abuse
Technology Enhanced Adolescent Mental Health (TEAM)
Adolescent nonsuicidal self-injury (NSSI) and alcohol misuse, alone and especially in combination, portend significant functional impairment in adulthood (e.g., relationship dysfunction, depression, suicidality).
- Conditions
- Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
- Trial name
- TEAM (NCT05343039)
- Testing
- Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Suicide, Adolescent Behavior
Wearable Suicidal Early Warning System for Adolescents
This study is prospectively enrolling a cohort of adolescent patients who present to the Emergency Department and an inpatient psychiatric adolescent unit with acute suicidality.
- Trial name
- NCT03030924
- Testing
- Solace
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Suicide and Self-harm
The Effect of a Brief Psychological Intervention on Reducing Self-harm Repetition: Feasibility Study
Recent research has focused on examining brief interventions for reducing self-harm, such as the volitional help sheet (VHS). The VHS is a theory-based psychological intervention.
- Trial name
- NCT03376113
- Testing
- the volitional help sheet
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- National Taiwan University Hospital
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Self-harm, Emotion Regulation
Feasibility of Emotion Regulation Group Therapy for Adolescent Self-Harm
Deliberate self-harm (DSH) is a prevalent behaviour among adolescents but there is no current recommendation for an efficacious treatment.
- Conditions
- Self-harm, Emotion Regulation, Adolescent - Emotional Problem
- Trial name
- ERGT-A (NCT06297824)
- Testing
- ERGT-A
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Depression, Anxiety
Digital Mental Health Service for Non-Treatment Seeking Young Adults
This is a feasibility trial of a personalized 8-week text messaging intervention aimed at young adults (ages 18-25) with depression and anxiety who are not interested in -- or experience barriers to -- receiving traditional…
- Conditions
- Depression, Anxiety, Suicidal Ideation
- Trial name
- NCT04948268
- Testing
- Adaptive messaging intervention, Non-personalized messaging intervention, Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Suicidal and Self-injurious Behavior
A Feasibility Open Trial of App-Enhanced Brief CBT for Suicidal Inpatients
The purpose of this study is to evaluate the feasibility of integrating Brief Cognitive-Behavioral Therapy (BCBT) counseling with a software application (app) to prevent future suicidal thoughts and behaviors.
- Trial name
- NCT05486091
- Testing
- App-Enhanced Brief Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Hartford Hospital
Lethal Means Safety
Leveraging Video Vignettes and Social Media to Promote Safe Firearm Storage Among Veterans
Family and friends are trusted by Veterans, and can play a vital role in supporting Veteran suicide prevention. Veterans are more likely to adopt secure firearm storage if their loved ones discuss firearm safety with them and if…
- Trial name
- WAV (NCT07756697)
- Testing
- WAV videos, VA News videos, VA LMS brochure
- Where
- United States
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development