Clinical trials: Self Medication, open to volunteers
Symptomatic Intracranial Atherosclerotic Stenosis
Drug- Eluting Stent for Symptomatic Intracranial Arterial Stenosis
This investigation is a prospective, multicenter, randomized controlled, non-inferiority clinical trial, to evaluate the safety and efficacy of the investigational device against alternative models/specifications of the control…
- Trial name
- DESIAS (NCT07197970)
- Testing
- NxiDIME™ Intracranial Drug-Eluting Stent System, NOVA DES Intracranial Drug-Eluting Stent
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Tiantan Hospital
Obesity and Metabolic Syndrome
Auricular Acupressure Integrated With a Smartphone Application for Weight Reduction
The goal of this clinical trial is to learn whether self-administered auricular acupressure integrated with a smartphone application works to reduce weight in patients with obesity accompanied with obesity-related comorbid…
- Trial name
- NCT06744933
- Testing
- Self-administered auricular acupressure integrated with a smartphone application
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people
- Sponsor
- Tung Wah College
Constipation, Psychiatric Drug Induced Constipation
Effectiveness of Self-Administered Acupressure Intervention in Managing Constipation of Adult Psychiatric In-Patient
Constipation is a common gastrointestinal condition characterized by unsatisfactory defaecation as a result of infrequent stools, difficult stool passage, or both.
- Conditions
- Constipation, Psychiatric Drug Induced Constipation, Constipation Drug Induced
- Trial name
- NCT07039448
- Testing
- Acupressure
- Where
- Hong Kong
- Volunteers
- 154 people
- Sponsor
- Hong Kong Metropolitan University
Diabetes (DM), Medicine, Chinese Traditional
Pilot RCT of a Chinese Medicine Diabetes Education Programme
The goal of this clinical trial is to learn if a Chinese medicine diabetes education programme is feasible and acceptable, and to explore its preliminary effects on self-management, for adults with type 2 diabetes in Hong Kong.
- Trial name
- NCT07758413
- Testing
- Chinese Medicine Diabetes Education Programme
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Epilepsy, Refractory Epilepsy
Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application
This is a prospective, placebo-controlled, double-blinded randomized study of self-administered auditory intervention in a naturalistic home environment.
- Conditions
- Epilepsy, Refractory Epilepsy, Music
- Trial name
- SONATA (NCT06425029)
- Testing
- Experimental Intervention (Music A), Active Comparator Intervention (Music B), Active Comparator Intervention (Music C)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Behavioral Symptoms, Suicide
Natural History of Depression, Bipolar Disorder and Suicide Risk
Mood disorders, such as depression and bipolar disorder, are difficult to treat. One reason is that there are no objective ways to measure how these disorders affect the body and respond to different treatments.
- Conditions
- Behavioral Symptoms, Suicide, Self-Injurious Behavior, Sensory System Agents
- Trial name
- NCT06462196
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Mental Health (NIMH)
Cardiovascular Diseases, Heart Diseases
WomenFocused Education in CArdiac REhabilitation (WECARE) Pilot RCT
The goal of this pilot clinical trial is to learn if a women-focused education program can improve knowledge, health, and well-being in women with heart disease who are attending cardiac rehabilitation.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Health Knowledge, Attitudes, Practice, Behavior, Health
- Trial name
- WE-CARE (NCT07550036)
- Testing
- Cardiac College for Women, Usual Cardiac Rehab Education
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Haemodialysis
The Effect of Education Based on Orem's Self-Care Deficit Theory and Tele-Monitoring on Rational Drug Use in Haemodialysis Patients
Patients with chronic kidney disease may show altered pharmacokinetic and pharmacodynamic response to many drugs compared to patients with normal renal function.
- Trial name
- Haemodialysis (NCT06689228)
- Testing
- Rational Drug Use Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Colorectal Neoplasms, Cancer Survivors
A Study on the Efficacy of the Metaverse Lifestyle Health Education Model Based on the Transtheoretical Model for Improving Quality of Life and Modifying Lifestyle in Colorectal Cancer Survivors
Colorectal cancer is a globally prevalent malignant tumor. Postoperative patients often face physical discomfort, psychological stress, and lack of healthy lifestyles.
- Trial name
- NCT07362823
- Testing
- TTM-Based Metaverse Lifestyle Health Education
- Volunteers
- 174 people
- Sponsor
- Qu Shen
Rhumatoid Arthisis, Spondyloarthritis (SA)
Efficacy of a Self-Management Smartphone App to Improve Safety Skills in Patients With Inflammatory Arthritis
Rheumatoid arthritis (RA) and spondyloarthritis (SpA), including psoriatic arthritis (PsA), are chronic painful diseases that impair quality of life.
- Conditions
- Rhumatoid Arthisis, Spondyloarthritis (SA), Psoriatic Arthritis (PsA)
- Trial name
- RHUMATOSMART (NCT07460739)
- Testing
- SFR application
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Firearm Injury
Store Safely: Rural Firearm Injury Prevention for Families
The researchers are testing a firearm safety prevention strategy tailored for families with children who reside in a rural area. Researchers hypothesize that the intervention will lead to improvements in household firearm storage.
- Trial name
- NCT06719713
- Testing
- Store Safely
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Medication Adherence, Glycemic Control for Diabetes Mellitus
A Nurse-Led Personalized Self-Management Counseling Intervention to Improve Medication Adherence and Glycemic Control in Adults With Type 2 Diabetes: A Randomized Controlled Trial
T2D is a chronic disease that forces people with diabetes to take their medications as prescribed and adhere to the recommended self-care practices to control their blood sugar and prevent complications.
- Trial name
- SMCI (NCT07920042)
- Testing
- Nurse-Led Personalized Self-Management Counseling
- Where
- Iraq
- Volunteers
- 128 people
- Sponsor
- University of Basrah
Chronic Obstructive Pulmonary Disease
Digital Therapy in Self-management of COPD Patients
This project adopts a whole-process digital therapy intervention package composed of an inhalation technique assessment device, an electronic inhalant medication monitoring device and digital software to guide patients use the…
- Trial name
- NCT06776601
- Testing
- Full process digital therapy intervention package
- Where
- China
- Volunteers
- 600 people
- Sponsor
- China-Japan Friendship Hospital
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Breast Cancer, Cancer
Digital Patient Support Program for Self-efficacy and Medication Adherence in Women on Adjuvant Endocrine Treatment for Breast Cancer
This is a randomized, controlled study to assess the effect of Sidekick Health's digital program on self-efficacy and medication adherence in breast cancer patients prescribed adjuvant anti-hormonal treatment.
- Trial name
- NCT06989450
- Testing
- Sidekick digital patient support program for patients with breast cancer, Standard of care for breast cancer patients
- Where
- Iceland
- Volunteers
- 140 people
- Sponsor
- Sidekick Health
PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder
Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision.
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD)
- Trial name
- STRIDES2 (NCT06923423)
- Testing
- Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
- Where
- 6 sites in United States
- Volunteers
- 640 people
- Sponsor
- University of Arkansas
Nursing Students
Puzzle-Based Learning on Nursing Students' Parenteral Medication Knowledge and Motivation
This randomized, controlled, parallel-group, interventional study aims to evaluate the effects of Crossword-Based Learning for Parenteral Drug Administration on the knowledge level, self-efficacy perception, and learning…
- Trial name
- → PIM-Crosswor (NCT07544810)
- Testing
- Puzzle-Based Learning Activity
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multimorbidity
Co-design of a Seamless Person-centered Intervention to Optimize Medication Use Across Healthcare Levels
Multiple long term conditions entails various needs for complex medication treatment, which is a huge clinical challenge considering medication interactions and disease-medication interactions.
- Trial name
- CIRCLE (NCT05421143)
- Where
- Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Malin Olsen Syversen
Childhood Obesity, Treatment Adherence
The Evira Study: Additional Support During Obesity Treatment
The goal of this clinical trial is to evaluate the effect of adding a digi-physical treatment tool as a complement to the local treatment with obesity medication in adolescents with obesity.
- Trial name
- NCT06836284
- Testing
- Digi-physical treatment tool, Evira, Obesity medication with liraglutide or semaglutide
- Where
- 3 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet