Clinical trials: Self Regulation
Emotional Regulation
Examining the Impacts of Parent Mightier Play
A randomized controlled trial comparing a group in which only child participants play Mightier video games for 8 weeks (Child Play group) to a group in which child and parent participants play Mightier video games for 8 weeks…
- Trial name
- NCT05080647
- Testing
- Mightier online gameplay
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Neuromotion Labs
Healthy Male Subjects
Drug Interaction Between SHR4640 Tablets and Furosemide Tablets in Healthy Volunteers (Single Center, Single Arm, Open, Self-control)
The purpose of this study was to evaluate the effect of SHR4640 tablets on the pharmacokinetics of furosemide tablets in healthy male volunteers, using a single-center, single-arm, open, self-control design.
- Trial name
- NCT04850638
- Testing
- SHR4640 tablets and furosemide tablets
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Bronchiectasis
Autologous Bronchial Basal Cells Transplantation for Treatment of Bronchiectasis
Bronchiectasis is a result of chronic inflammation compounded by an inability to clear mucoid secretions. Inflammation results in progressive destruction of the normal lung architecture, in particular the elastic fibers of…
- Trial name
- NCT02722642
- Testing
- Bronchial basal cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Regend Therapeutics
Emotional Regulation
Examining the Impacts of Parent-Child Interactive Activities
The purpose of this study is to demonstrate the effects of online and offline play of games on the Mightier game platform, in comparison to the effects of Mightier online play alone.
- Trial name
- NCT04839861
- Testing
- Mightier Family Games, Mightier online gameplay
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Neuromotion Labs
Healthy Subjects
Effect of Rifampicin on the Pharmacokinetics of SHR6390 in Healthy Subjects
The primary objective of the study is to evaluate the effect of rifampicin on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR6390 tablets.
- Trial name
- NCT04439578
- Testing
- SHR6390 tablet single oral dose of SHR6390 or co-administered with rifampicin
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Liver Cancer, Pancreas Cancer
A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain
A prospective, multicenter, self-control clinical trial aim to enroll 110 patients suffered from upper abdominal (liver, pancreas, stomach, etc.) cancers .
- Conditions
- Liver Cancer, Pancreas Cancer, Stomach Cancer, Bile Duct Cancer
- Trial name
- NCT04014478
- Testing
- Endovascular Denervation
- Volunteers
- 110 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Diabetes, Diabetes Mellitus, Type 2
Self-control Trial to Evaluate the Remission Rate in Newly Diagnosed Type 2 Diabetes Patients After Treatment With Insulin Aspart
This trial is conducted in Asia. The aim of this trial is evaluate the remission rate in newly diagnosed subjects with type 2 diabetes after short-term intensive treatment with insulin aspart and insulin NPH.
- Trial name
- NCT00494988
- Testing
- insulin aspart, insulin NPH
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Novo Nordisk A/S
Emotional Regulation
Adding Printed CBT Materials to a Pediatric Digital Intervention
The primary goal of this study is to demonstrate that engaging with "offscreen" physical materials that focus on teaching and practicing Cognitive Behavioral Therapy-based skills alongside a digital emotional regulation…
- Trial name
- NCT06580496
- Testing
- Mightier
- Volunteers
- 150 people
- Sponsor
- Neuromotion Labs
Hemophilia A
A Study to Evaluate the Pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection
Primary objective: To assess the pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc fusion protein for Injection at two dose levels in patients with hemophilia A.
- Trial name
- NCT03747653
- Testing
- ADVATE, FRSW107
- Where
- 5 sites in China
- Volunteers
- 12 people
- Sponsor
- Kaifeng Pharmaceutical (Group) Co., Ltd.
Healthy Subjects
Effect of Itraconazole on the Pharmacokinetics of SHR6390 in Healthy Subjects
The primary objective of the study is to evaluate the effect of itraconazole on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR6390 tablets.
- Trial name
- NCT04423601
- Testing
- SHR6390 tablet, Itraconazole capsule
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Advanced Solid Tumor
A Drug-drug Interaction Study of SHR6390 on Healthy Chinese Volunteers
The study is a single-center, open, single-dose, self-controlled clinical trial. It is planned to enroll 20 healthy adult subjects.Subjects will take the SHR6390 on Day1 and Day22 , and from Day8 to Day26 take the efavirenz.
- Trial name
- NCT04973020
- Testing
- SHR6390、efavirenz
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
PTSD, Emotion Regulation Disorders
Hybrid Dialectical Behavior Therapy for Veterans to Further Reduce Emotion Regulation Problems and Trauma Symptoms
Around 10% of post-active veterans experience post-traumatic stress disorder (PTSD) many years post-mission. PTSD in veterans is frequently associated with challenges in emotion regulation, aggression, suicidality, and financial…
- Conditions
- PTSD, Emotion Regulation Disorders, Substance Abuse
- Trial name
- REFRESH (NCT07652645)
- Testing
- Hybrid dialectical behavior therapy
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Arkin
Healthy Subjects
Effect of Itraconazole on the Pharmacokinetics of Pyrotinib in Healthy Subjects
The study will assess the effect of multiple oral doses of itraconazole on the single dose pharmacokinetic parameters of pyrotinib in healthy Chinese subjects.
- Trial name
- NCT04479891
- Testing
- pyrotinib tablet, Itraconazole capsule
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Emotional Dysregulation, Therapeutic Alliance
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems.
- Conditions
- Emotional Dysregulation, Therapeutic Alliance, Depression Disorder, Anxiety Disorders
- Trial name
- HEAL-SLOJSC (NCT07364799)
- Testing
- Multi-sensory emotional regulation intervention (Heal)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- SoundHeal
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD
Evaluation of a Novel Quantum-Inspired Intervention (QII) for Children With Autism Spectrum Disorder: A Global Confirmatory Study
The purpose of this global multicenter confirmatory study is to evaluate the clinical efficacy and safety of Quantum-Inspired Intervention (QII), a novel non-invasive neurodevelopmental protocol, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, ASD
- Trial name
- NCT07898787
- Testing
- Quantum-Inspired Intervention (QII)
- Volunteers
- 80 people
- Sponsor
- BlissBot, Inc
Risky Sexual Behavior, Emotional Regulation
Education Program to Reduce Risky Behavior in Adolescents Ph I
This phase will complete the TRAC adaptation to a web app. The pilot study (R21 HD089979) effectively translated the ER content of TRAC and the same procedures will be used to translate the remaining content.
- Conditions
- Risky Sexual Behavior, Emotional Regulation, Adolescent Behavior
- Trial name
- iTRAC (NCT05607784)
- Testing
- Formative Research- Content Translation, Formative Research- Content Feedback and Acceptability
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Klein Buendel, Inc.
Emotional Regulation, Problem Behavior
Examining the Impacts on In-School Behaviors of In-Home Videogame Play
The proposed study aims to investigate the effects of children's in-home engagement with a biofeedback video game-based intervention on children's in-school behaviors.
- Conditions
- Emotional Regulation, Problem Behavior, Irritable Mood
- Trial name
- NCT05260398
- Testing
- Mightier Online Gameplay
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Neuromotion Labs
Myocardial Ischemia
Pressure Guidewire System Multi-center, Prospective, Self-Control, Clinical Trial
Patients with intermediate-grade coronary stenosis undergo measurement of fractional flow reserve using the test article (Zurich Pressure Guidewire System) and predicate article (Abbott PressureWire System).
- Trial name
- NCT04582877
- Testing
- FFR measurement
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zurich Medical Inc.
Anxiety
Correlates of Anxiety Associated With a Life-threatening Illness
The goal of this observational trial is to gather brain scan data on people undergoing MDMA-assisted therapy. The main question it aims to answer is: -How does brain activity change while completing an emotional regulation task…
- Trial name
- NCT02954562
- Testing
- fMRI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Resilient Pharmaceuticals
Risky Sexual Behavior, Emotion Regulation
An Interactive Education Program to Reduce High Risk Behavior in Adolescents Ph II (iTRAC HERO)
Using the efficacious iTRAC intervention to enhance emotion regulation competencies as a foundation, this study will create and test iTRAC-HERO to teach emotion regulation skills in the context of sexual health education.
- Conditions
- Risky Sexual Behavior, Emotion Regulation, Adolescent Behavior
- Trial name
- iTRAC-HERO (NCT06894277)
- Testing
- iTRAC-HERO
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Klein Buendel, Inc.