Clinical trials: Self-control
Insomnia (moderate)
Impact of GABA Probiotic Lactiplantibacillus Plantarum Lp815 on Sleep Outcomes in Participants with Self-Reported Sleep Disturbance
The rationale for this study is to observe differences in sleep outcomes between a consumer-grade probiotic capsule called GABA Probiotic and a placebo control group.
- Trial name
- NCT06789718
- Testing
- GABA Probiotic Lactiplantibacillus plantarum Lp815 (5 Billion cfu/dose), Optional Sub-Study: Neurotransmitter Urine Test
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Verb Biotics LLC
Bipolar Depression, Suicidal Ideas
Sequential Therapy for the Treatment of Severe Bipolar Depression.
NeuroRx is developing NRX-101, a fixed-dose combination oral capsule composed of d-cycloserine (DCS) and lurasidone for the maintenance of remission from Severe Bipolar Depression with Acute Suicidal Ideation (C-SSRS level 4 or…
- Conditions
- Bipolar Depression, Suicidal Ideas, Suicidal Ideation, Suicide, Attempted
- Trial name
- STABIL-B (NCT02974010)
- Testing
- NRX-101 Oral Capsule, Lurasidone Oral Capsule, Ketamine Intravenous Infusion
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- NeuroRx, Inc.
Attention Deficit/Hyperactivity Disorder (ADHD)
The Efficacy and Safety of Phosphatidylserine-Omega3 in Children With Attention-Deficit/ Hyperactivity Disorder
The primary objective of this trial is to determine whether an oral administration of Phosphatidylserine-Omega3 would significantly improve the clinical symptoms of children suffering from ADHD.
- Trial name
- NCT00418184
- Testing
- Phosphatidylserine-Omega3, Colored cellulose tainted with fishy odor
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Enzymotec
ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Drug-Drug Interactions of JMKX003142 in Healthy Participants
This is a single-center, non-randomized, open-label, self-controlled, Phase I clinical trial to evaluate the drug-drug interactions (DDI) of JMKX003142 tablets in healthy adult participants.
- Trial name
- NCT07565441
- Testing
- JMKX003142 tablets, Fluconazole Capsules, Cocktail Substrates (Midazolam Oral Solution, Rosuvastatin Calcium Tablets, and Digoxin Tablets)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Jemincare
Asthma, Bronchial Diseases
Asthma Data Innovation Demonstration Project
Propeller Health is collaborating with the City of Louisville and other local partners to carry out a focused demonstration project that will evaluate the effectiveness of the Propeller Health approach to asthma management while…
- Conditions
- Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive
- Trial name
- ADID (NCT02162576)
- Testing
- Propeller Health intervention
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- David Van Sickle
Solid Tumor, Adult
Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects
This is an open-label, non-randomized, clinical study to evaluate the drug interaction between itraconazole, rifampin or Cocktail and JMKX001899 in healthy subjects.
- Trial name
- NCT06348290
- Testing
- JMKX001899, Itraconazole, Midazolam
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jemincare
Burns
Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
The investigation is designed as an open, non-controlled, post-marketing investigation. Subjects with at least one second degree burn less than 9.5x15 cm in size at 1-3 sites will be included.
- Trial name
- NCT01418482
- Testing
- Mepilex Border Ag
- Where
- 2 sites in Sweden
- Volunteers
- 15 people
- Sponsor
- Molnlycke Health Care AB
Laryngectomy; Status
Evaluation of the Safety and Efficacy of Voice Prosthesis in Voice Reconstruction After Total Laryngectomy
The objective of the study is to evaluate the clinical safety and efficacy of voice prosthesis for voice reconstruction after total laryngectomy in China.
- Trial name
- NCT05482815
- Testing
- Provox Vega Voice prosthesis
- Where
- 3 sites in China
- Volunteers
- 80 people
- Sponsor
- Atos Medical AB
Myocardial Ischemia
Pressure Guidewire System Multi-center, Prospective, Self-Control, Clinical Trial
Patients with intermediate-grade coronary stenosis undergo measurement of fractional flow reserve using the test article (Zurich Pressure Guidewire System) and predicate article (Abbott PressureWire System).
- Trial name
- NCT04582877
- Testing
- FFR measurement
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zurich Medical Inc.
Overweight, Obesity
Weight Loss Using the Take Shape For Life Program or the Medifast Direct Program Versus a Self-Directed Diet
The study evaluates the effects of two commercially available weight loss programs, the TSFL and the MEDD programs, each compared to a self-directed control diet, on changes in body weight over a 16-week weight loss phase, in…
- Trial name
- NCT02835092
- Testing
- Take Shape For Life Program, Medifast Direct Program, Self-directed Control
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
PreDiabetes, Diabetes Mellitus, Type 2
Transform Type 2: Examining Meal-Delivery and Education for Diabetes Self-Care
The purpose of this research is to understand the impact of medically tailored meals on health-related biometrics (e.g., glucose time-in-range, waist-hip ratio, cholesterol) and how providing medically tailored meals promotes…
- Trial name
- NCT04810026
- Testing
- Education, Meal delivery, Lifestyle coaching
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- UnitedHealth Group
Low Back Pain
The Kaia Back Pain Intervention for Self-management of Low Back Pain
The study aims to evaluate outcomes of the use of Kaia Study app (software program application for self-management of low-back pain) on back pain among adults with non-specific subacute and chronic low back pain based on change…
- Trial name
- BACKSPIN (NCT04290078)
- Testing
- Kaia Back Pain Study App, Usual Care
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Kaia Health Software
Hair Thinning
Nutraceutical Supplement With Standardized Botanicals in Males With Thinning Hair
The objective of this study is to assess the effectiveness and safety of a novel dietary supplement containing botanical ingredients for hair thinning in men over the course of six months of continuous daily usage.
- Trial name
- NCT05339958
- Testing
- Nutrafol® Men Hair Growth Nutraceutical
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Nutraceutical Wellness Inc.
Hypothyroidism
Study of XP-8121 For the Treatment of Adult Subjects With Hypothyroidism
This is a non-randomized, open-label, single arm, self-controlled study of XP-8121 (levothyroxine sodium) to determine a target dose conversion factor from stably dosed oral levothyroxine to XP-8121 (levothyroxine sodium) in…
- Trial name
- NCT05823012
- Testing
- levothyroxine sodium
- Where
- 6 sites in United States
- Volunteers
- 46 people
- Sponsor
- Xeris Pharmaceuticals
Mental Health
Mindfulness and Acceptance Applied in Colleges Through Web-Based Guided Self-Help (Phase II)
This study will develop and then test a web-based guided self-help version of Acceptance and Commitment Therapy (ACT) to be utilized at college counseling centers (CCCs).
- Trial name
- NCT02761681
- Testing
- ACT-CL Web-based guided self-help, Control Web-based guided self-help
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Contextual Change LLC
Contraception
Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use
This study is designed to assess whether consumers select and use norgestrel 0.075 mg, a progestin only pill for contraception, in a manner consistent with the OTC package directions in an Over-the-Counter (OTC)-like setting.
- Trial name
- ACCESS (NCT04112095)
- Testing
- Norgestrel 0.075 mg tablets
- Where
- 38 sites in United States
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Suicide, Attempted, Suicidal Ideation
A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic
The primary objective of this study is to assess the effectiveness of a digital intervention in reducing suicide attempts.
- Trial name
- NCT05144685
- Testing
- OTX-202, OTX-000, Treatment as Usual
- Where
- 6 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Oui Therapeutics, Inc.