Clinical trials: Self-harm, open to volunteers
Suicide, Suicide Attempt
Evaluation of a Telehealth Case Management Intervention to Prevent Suicide Among Soldiers Discharged From Psychiatric Hospitalization
This study evaluates the effectiveness of Pathfinding, a 6-month, remotely-delivered case management intervention designed to decrease suicidal behavior among active-duty Regular Army soldiers recently discharged from inpatient…
- Trial name
- NCT07404787
- Testing
- Pathfinding, Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Uniformed Services University of the Health Sciences
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Suicide
Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans
Mental health care for Veterans with suicidal symptoms is of paramount import to the VA. Unfortunately, VA suicide reports show suicide rates increasing, suggesting a need for enhancing current VA suicide mental health care…
- Trial name
- NCT04731519
- Testing
- Continuous Identity Cognitive Therapy (CI-CT), General Health Education
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- VA Office of Research and Development
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide, Suicidal Ideation
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today.
- Conditions
- Suicide, Suicidal Ideation, Suicide Attempt
- Trial name
- SP-BSC (NCT07125144)
- Testing
- Black Youth Suicide Prevention in Chicago, Signs of Suicide: Standard/Existing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Suicide
Mobile Intervention for Suicidal Thoughts
One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel.
- Trial name
- NCT06593379
- Testing
- Safety planning, Treatment as usual, MIST Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Teen Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- Teen RISE (NCT07170657)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder, Opioid Use Disorder
Cortical rTMS as a Treatment for Depression
Depression is a leading cause of disability worldwide with a 19% lifetime prevalence in the United States. Dysfunctional reward processing is one of the core features of depression.
- Conditions
- Major Depressive Disorder, Opioid Use Disorder, Suicidality
- Trial name
- NCT05487911
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Autism, Suicide Prevention
Crisis Interventions for Pediatric Providers - Autism Version
The goal of this clinical trial is to examine the initial feasibility, acceptability, and effectiveness of Crisis Interventions for Pediatric Providers - Autism version (CIPP-A) for providers serving autistic youth in outpatient…
- Trial name
- NCT07508436
- Testing
- Safety Planning Intervention, Crisis Interventions for Pediatric Providers - Autism version (CIPP-A)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
PTSD, Post Traumatic Stress Disorder
Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or…
- Conditions
- PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
- Trial name
- CAPER (NCT06222268)
- Testing
- Cannabidiol (CBD) only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Leslie Lundahl
Suicidal Ideation, Suicide Attempt
The Epidemiology of Suicide Attempts and Suicidal Thoughts in Flanders
The objective of this study is to collect data in Flanders on the incidence of suicide attempts and suicidal ideation across various healthcare settings.
- Conditions
- Suicidal Ideation, Suicide Attempt, Multicenter Study, Epidemiological Study
- Trial name
- BC-03869 (NCT07021404)
- Testing
- Semi-structured interview (Guideline for Suicide care and Evaluation =LOES)
- Where
- 33 sites in Belgium
- Volunteers
- 50,000 people
- Sponsor
- University Hospital, Ghent
Anxiety, Suicidal Ideation
Climate Anxiety in a Young Population at Risk of Suicide
Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated…
- Conditions
- Anxiety, Suicidal Ideation, Mental Health Issue, Environmental Exposure
- Trial name
- Anx-RS (NCT07305688)
- Testing
- Columbia Suicide Severity Rating Scale, Climate Change Anxiety Scale - French version, State-Trait Anxiety Inventory, French version
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Esquirol
Suicide, Attempted, Suicidal Ideation
Brief Cognitive Behavioral Therapy Replication Trial
The overall goal for the proposed project is to test the effectiveness of BCBT for the prevention of suicide attempts in a sample of treatment-seeking U.S. military personnel and veterans.
- Trial name
- NCT03769259
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Suicide Prevention
HAVEN-Connect Youth Suicide Prevention
HAVEN=CONNECT is a comprehensive depression and suicide prevention intervention that is designed to be integrated into predominantly Black churches, a strategically ideal location for mental health intervention for Black youth.
- Trial name
- HAVEN (NCT07401940)
- Testing
- HAVEN-Connect, HAVEN Suicide Prevention
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- George Washington University
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University