Clinical trials: Self-harm Behavior
Bipolar Disorder
Observation of Clozapine Treatment Safety in Bipolar Disorder.
The purpose of the registry is to record incidence of adverse events during treatment with clozapine in patients suffering from bipolar disorder.
- Trial name
- CloGD (NCT06011460)
- Testing
- Clozapine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Gdansk
Self-Injurious Behavior
Self-Injury Treatment and Recovery in Veterans
Nonsuicidal self-injury (NSSI) refers to the intentional destruction of one's own body tissue without suicidal intent and for purposes that are not socially sanctioned.
- Trial name
- STRIVe (NCT05969080)
- Testing
- Treatment for Self-Injurious Behaviors, Treatment As Usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Comorbidity, Substance Abuse
ENGAGE - Meeting Mental Health Needs of Complex Comorbid Patients
Scotland has higher rates of suicide than other parts of the UK, an average rate of 15.1 per 100,000 in Scotland compared to 11.4 for England and Wales. The Scottish Government is committed to reducing suicide by 2013.
- Conditions
- Comorbidity, Substance Abuse, Personality Disorder
- Trial name
- ENGAGE (NCT00980824)
- Testing
- Cognitive behavioural therapy, Standard treatment
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Glasgow
Substance Use Disorders, Depression
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
The overall aim of this pilot study is to conduct a preliminary trial to evaluate the acceptability and feasibility of adding a transdiagnostic, emotion-focused group intervention (the Unified Protocol, UP) to treatment as usual…
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder
- Trial name
- ARMS UP (NCT03315208)
- Testing
- Unified Protocol (UP), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Suicide Prevention
Integrating Suicide Prevention Packages Into Task-shifted Mental Health Interventions in Low-resourced Contexts
The goal of this study is to assess the feasibility and acceptability of implementing a co-designed suicide prevention package of implementation strategies (SuPP) in a pilot open, non-randomized, clinical trial.
- Trial name
- NCT06094959
- Testing
- Suicide Prevention Package
- Where
- Nepal
- Volunteers
- 37 people
- Sponsor
- Yale University
Major Depressive Disorder, Suicidal Behavior
Basal Plasma Lithium Levels and Suicidal Events
Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.
- Conditions
- Major Depressive Disorder, Suicidal Behavior, Bipolar Disorder
- Trial name
- LIPS (NCT05409794)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation
Effectiveness of a CBT Online-based Program to Reduce Suicide Ideation Among School Adolescents
This is a single-blind two armed cluster randomized controlled trial (cRCT) aimed to determine the effectiveness of an integrated blended intervention (online a face-to face sessions) to reduce suicidal ideation (primary…
- Trial name
- NCT05229302
- Testing
- Reframet IT, Usual care
- Where
- Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Talca
Personal History of a Recent Suicidal Crisis, Suicidal Ideation
SmartCriseS - Smartphone Survey of Suicidal Risk
Sleep and appetite disorders as well as social exclusion, have been linked to the emergence of suicidal ideation (SI) and suicide attempts.This study aims to evaluate the relationship between those factors and suicidal ideation…
- Conditions
- Personal History of a Recent Suicidal Crisis, Suicidal Ideation, Suicidal Behaviour
- Trial name
- SmartCriseS (NCT03720730)
- Testing
- EMA
- Where
- 2 sites in France, Spain
- Volunteers
- 1,044 people
- Sponsor
- University Hospital, Montpellier
Adolescent Behavior, Suicidal Ideation
Navigating Mental Health Treatment for Black Youth
This study looks to conduct a systematic adaptation of Suicidal Teens Accessing Treatment (STAT-ED) for Black youth presenting in the emergency department who have suicide risk.
- Trial name
- NCT05334381
- Testing
- Adapted STAT-ED, Standard Enhanced Treatment As Usual
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Suicide
Preventing Suicide in African American Adolescents
The overarching aim of the Success Over Stress Prevention Project is to reduce African American youth suicide. This study examines the impact of a 15-session, group-delivered, culturally-grounded, cognitive-behavioral…
- Trial name
- NCT04253002
- Testing
- Robinson's Culturally Adapted Coping with Stress Course (A-CWS), Standard Care Control Condition
- Where
- 6 sites in United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- DePaul University
BPH, Depression
5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression
In December 2015, Health Canada issued a warning about a potential relationship between suicide and finasteride use and called for further research.
- Conditions
- BPH, Depression, Suicide
- Trial name
- NCT02876757
- Testing
- 5ARI
- Volunteers
- 186,394 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Children, Adolescents
Validation of the Ask Suicide-Screening Questions (ASQ) in the Inpatient Medical Setting
Physicians and nurses working in non-mental health settings require tools to guide them in recognizing patients at risk. While screening children and adolescents is emerging as a priority of the Joint Commission, there are…
- Trial name
- NCT02050867
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- National Institute of Mental Health (NIMH)
Suicide
A Community Intervention Trial of Multimodal Suicide Prevention Program in Japan (NOCOMIT-J)
1. The primary goal for this study is to examine the effectiveness of community-based multimodal intervention program for suicide prevention in relatively high suicide rate region compared to control region. 2.
- Trial name
- NOCOMIT-J (NCT00737165)
- Testing
- Multimodal suicide prevention program, Suicide prevention program as usual
- Where
- 7 sites in Japan
- Volunteers
- 1,951,060 people
- Sponsor
- Japan Foundation for Neuroscience and Mental Health
Suicide, Suicide, Attempted
Drivers of Suicide Mobile App Study
The central purpose of this project is to evaluate and facilitate access to evidence-based best practices for individuals struggling with suicidal ideation and co-occurring behavioral problems, including alcohol misuse, and…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Alcohol Use Disorder
- Trial name
- NCT05427734
- Testing
- WisePath for Adults, Active-Control app + electronic wellness resources brochure
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Help-Seeking Behavior, Emotions
Mobile Phone Intervention to Reduce Youth Suicide in Rural Communities
The goal of this research project is to conduct a pilot RCT of Text4Strength, an interactive automated text messaging extension of Sources of Strength (SoS), a universal school-based suicide prevention program that prepares…
- Conditions
- Help-Seeking Behavior, Emotions, Trusted Adults, Suicide
- Trial name
- NCT03145363
- Testing
- Intervention, Control
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Alcohol Drinking, Suicide
mHealth-supported Skills Training for Alcohol-Related Suicidality
Suicide is a high priority public health problem and an increasingly prevalent alcohol-related consequence. One-third of people who die by suicide consume alcohol at hazardous rates in the year preceding death.
- Trial name
- mSTARS (NCT05847504)
- Testing
- mSTARS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Suicidal Ideation
Think Life, an Online Self-help Intervention for Coping With Suicidal Ideation
The objective of the Think Life study is to test the effect of an online, unguided self-help intervention, i.e. Think Life. The primary hypothesis is that Think Life will reduce suicidal ideation.
- Trial name
- NCT03209544
- Testing
- Online self-help intervention
- Volunteers
- 724 people
- Sponsor
- University Ghent
Mental Health Wellness 1
Assessing Online Interventions for Men's' Mental Health and Wellbeing
The purpose of this study is to test a comprehensive, male-oriented, online screening and referral (Screening for Mental Health; SMH) and male-oriented online information and referral intervention program (Man Therapy; MT) to…
- Trial name
- NCT02785471
- Testing
- Screening for Mental Health only, Screening for Mental Health & Man Therapy
- Where
- United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Suicide
Circle of Life. Improving Capacity of Swampy Cree Community Members to Recognize People at Risk for Suicide
Primary Hypothesis: Participants in the Applied Suicide Intervention Skills Training (ASIST) gatekeeper training will be significantly more likely to have increased knowledge and preparedness to help people with suicidal ideation…
- Trial name
- NCT01287416
- Testing
- Applied Suicide Intervention Skills Training, Resilience Retreat
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Suicide
STAT-ED: Suicidal Teens Accessing Treatment After an Emergency Department Visit
This study looks to implement a novel intervention (STAT-ED) for children who screen positive to suicide ideation. The intervention looks to collect data from several different measures and then randomize participants into one of…
- Trial name
- STAT-ED (NCT01779414)
- Testing
- STAT-ED Intervention
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati