Clinical trials: Self-management
Chronic Low Back Pain, Self-Management
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress…
- Trial name
- PROPEL (NCT03637998)
- Testing
- Problem-solving Pain to Enhance Living Well (PROPEL)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Weight Cycling, Obesity & Overweight
Effect of Meal Frequency on Diet Self-Efficacy and Perceived Stress in Women With Weight Cycling
The World Health Organization (WHO) defines obesity as abnormal or excessive fat accumulation in the body that may adversely affect health.
- Conditions
- Weight Cycling, Obesity & Overweight, Dietary Self-efficiacy, Perceived Stress
- Trial name
- NCT07582952
- Testing
- 3-meal diet plan, A dietary intervention comprising 3 main meals and 3 snacks
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Medipol University
Diabetes Mellitus, Type 2, Patient Education as Topic
Differing Completion Rates of DIABETES Education on Patient Reported Outcomes
The goal of this clinical feasibility trial is to test the impact of differing completion rates of a face-to-face diabetes self-management education programme on patient-reported outcomes measuring self-care, diabetes distress…
- Trial name
- DIABETES-PRO (NCT06419907)
- Testing
- Type 2 Live Well (structured diabetes self management education programme)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Liverpool
COPD, COPD Exacerbation
Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting approximately 10% of the adult population globally.
- Trial name
- RAPID (NCT06347536)
- Testing
- Supported rescue pack
- Where
- 34 sites in United Kingdom
- Volunteers
- 1,400 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Diabetes
Improving Health Outcomes of Diabetic Veterans: A Diabetic Self-Management Program
Control of the blood sugar prevents complications and results in extra years of life in patients with diabetes. Practice Guidelines delineating specific ways physicians manage diabetes have been outlined.
- Trial name
- NCT00013052
- Testing
- Peer led classes. Led by trained veterans with a chronic disease.
- Where
- 3 sites in United States
- Volunteers
- 2,068 people
- Sponsor
- US Department of Veterans Affairs
Cannabis Use
Effect of Lorcaserin on Cannabis Withdrawal and Self-administration
In this study, the investigators are interested in testing how lorcaserin influences the effects of cannabis in a human laboratory model of cannabis use.
- Trial name
- NCT03253926
- Testing
- Lorcaserin, Marijuana
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Type 1 Diabetes Mellitus
An Evaluation of Internet-based Carbohydrate Counting Education for Adolescents With Type 1 Diabetes
Helping individuals with diabetes to control their blood sugars through self-management is an important goal, and counting carbohydrates (CHO) remains a key part of diabetes education and management.
- Trial name
- NCT02462785
- Testing
- In-person Carbohydrate Counting Class, Online Carbohydrate Counting Tutorial
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- The Hospital for Sick Children
Type 1 Diabetes
The REPOSE (Relative Effectiveness of Pumps Over MDI and Structured Education) Trial
For type-1 diabetes, the aim of insulin therapy is to keep blood glucose close to normal while avoiding hypoglycaemia but this is severely limited by the relative crudeness of current insulin delivery in comparison with the…
- Trial name
- REPOSE (NCT01616784)
- Testing
- CSII (Insulin Pump) plus DAFNE, MDI (levemir® & quick acting insulin) plus DAFNE
- Where
- 8 sites in United Kingdom
- Volunteers
- 267 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Opioid Use Disorder, Chronic Pain
Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment
This study seeks to improve the treatment of chronic pain in people who are taking buprenorphine (also known as Suboxone, Subutex, Zubsolv).
- Trial name
- TREETOP (NCT06367387)
- Testing
- Patient-Oriented Dosing (POD), Pain Self-Management (PSM), Usual Care
- Where
- 13 sites in United States
- Volunteers
- 273 people
- Sponsor
- Erin Winstanley
Influenza
Pharma-Pen (Formerly Innoject) Auto-injectory TIV
The purpose of this study is to evaluate the safety, effectiveness, and tolerability, of the Pharma-Pen(TM) intramuscular (IM) and subcutaneous (SC) auto-injector systems used by untrained users to self-administer Influenza…
- Trial name
- NCT00335855
- Testing
- Auto-injector for IM/SC vaccine administration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Renal Insufficiency
Effectiveness of Chronic Kidney Disease Nurse-led Self-management Program (CKD-NLSM)
This study aims to develop, implement and evaluate the effectiveness of a theory-driven nurse-led self-management intervention program compared to standard usual care in people with CKD stages 3-4 on CKD knowledge…
- Trial name
- CKD-NLSM (NCT03974646)
- Testing
- Nurse-led self-management Program
- Where
- Malaysia
- Volunteers
- 130 people
- Sponsor
- Universiti Putra Malaysia
Cancer
Patient Outcomes of a Self-care Management Approach to Cancer Symptoms: A Clinical Trial
Regardless of their treatment, cancer patients endure a variety of difficult symptoms during their disease with averages ranging from 7 to 14 symptoms each.
- Trial name
- NCT02288169
- Testing
- COPE, Support/Attention Control
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- University of South Florida
Urinary Incontinence
Improving Urinary Continence and Quality of Life in Prostate Cancer Patients
This intervention program combines biofeedback PFME with a telephone or support group intervention to treat persistent urinary incontinence (UI).
- Trial name
- NCT01365182
- Testing
- BF+SUPPORT, BF+PHONE
- Volunteers
- 279 people
- Sponsor
- Case Western Reserve University
PARKINSON DISEASE (Disorder)
Protocol of the Packer Managing Fatigue Program Versus Standard Information to Improve Energy Conservation Self-Efficacy in Parkinson's Disease
This protocol describes a randomized, controlled, parallel-group, trial evaluating the effectiveness of a group-based fatigue management program for people with Parkinson's disease.
- Trial name
- NCT07094269
- Testing
- Occupational Therapy Intervention, Fact-sheets
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita degli Studi di Genova
Workers on Sick-leave, Insured by The Danish Welfare State
Effects of a Self-management Course for Adults on Sick-leave
The purpose of the current study is to determine the efficacy of a self-management course for workers on sick-leave as an add-on to standard rehabilitation care and follow-up (treatment as usual).
- Trial name
- jos (NCT02136056)
- Testing
- Self-management program (SMP)
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- University of Aarhus
AUD
Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation
Background: Drugs like nalmefene interfere with opioid receptors. This might reduce drinking. The gene OPRM1 determines opioid receptor functions. Researchers want to see if nalmefene affects people s responses to alcohol cues.
- Trial name
- NCT02639273
- Testing
- Nalmefene
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type 2 Diabetes Mellitus (T2DM)
The Effect of Individualized Nursing Interventions on Glycemic Variability and Self-Management in Type 2 Diabetes
Type 2 diabetes is a chronic disease with an increasing prevalence worldwide and in our country. In managing type 2 diabetes, the primary goal in the nursing process is to ensure blood glucose stability.
- Trial name
- NCT06973395
- Testing
- Nursing interventions, education, and follow-up will be provided to Type 2 diabetes patients for blood glucose variability.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ataturk University
Cancer, Pain
Nasal Fentanyl for Chronic Cancer Pain
Today, patients with cancer pain in need of opioids for moderate to severe pain get long-acting morphine twice a day and morphine tablets taken on demand in addition.
- Trial name
- NFCP-2 (NCT01906073)
- Testing
- intranasal fentanyl spray, slow release morphine
- Sponsor
- Norwegian University of Science and Technology
Food Allergy in Children, Caregiver Burnout
The Psychosocial Outcomes in Caregivers of Children With Food Allergy
The purpose of this study is to evaluate use of a mobile application (also commonly referred to as an app) designed to support caregivers of children with newly diagnosed food allergy. This study has 2 phases.
- Conditions
- Food Allergy in Children, Caregiver Burnout, Psychosocial Problem, Family Research
- Trial name
- FASST (NCT04512924)
- Testing
- Enhanced mobile app with standard of care and education, Enhanced mobile app with standard of care, education and support resources
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorders, Anxiety
The Development of a Psychoeducational Tool to Manage Anxiety in People With Autism Spectrum Disorders
The purpose of this pilot intervention trial is to assess the efficacy of newly developed psychoeducation guides designed to manage anxiety in Autism Spectrum Disorder (ASD) by recruiting 30 participants with ASD and high levels…
- Trial name
- MANAGE (NCT02797379)
- Testing
- Psychoeducation
- Where
- 2 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- King's College London