Clinical trials: Semen Quality
Stress, Mood
Effect of Black Cumin Seed Oil Supplementation on Cortisol, Stress and Mood
The primary objective of this study will be to collect data to support the role of black cumin seed oil, also known as black seed oil (BSO), in moderating the stress response, including objective markers of stress (cortisol/DHEA)…
- Trial name
- NCT06950424
- Testing
- black cumin seed oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shawn Talbott
Infertility, Male
Microbiome Influence on Seminal Quality
The microbiome plays an important role in health and in some unknown etiologies. Some previous studies have identified bacteria in semen as a potential factor in male infertility.
- Trial name
- NCT04784260
- Testing
- Microbiome analysis
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Cancer, Treatment-Related, Late Effect
Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent…
- Conditions
- Cancer, Treatment-Related, Late Effect, Semen Analysis
- Trial name
- NCT06587477
- Testing
- Hormonal profile, Semen analysis, Questionnaire
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Antioxidants, Infertility, Male
Oxidative Stress In Semen And Male Infertility
The proposed research aims to study the effects of antioxidant therapy, commonly used in male infertility treatment, on semen analysis.
- Conditions
- Antioxidants, Infertility, Male, Semen Quality
- Trial name
- NCT03464656
- Testing
- Fairhaven Pro for men, Semen analysis, Sperm DNA fragmentation
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Autologous Platelet-rich Plasma Supplement, Sperm Cryopreservation
The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation on Post-cryopreserved Sperm Quality
Sperm cryopreservation is an essential procedure for male fertility in certain situations, like cancer, vasectomy or other obstructive surgeries, autoimmunity diseases, immunosuppressive therapeutic strategies, or when the male…
- Conditions
- Autologous Platelet-rich Plasma Supplement, Sperm Cryopreservation, Post-cryopreserved Sperm Quality, Semen Analysis
- Trial name
- NCT06258759
- Testing
- autologous platelet-rich plasma supplement, no autologous platelet-rich plasma supplement
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Obesity-related Male Infertility
Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health
Why is this study being done? Obesity can harm men's fertility by lowering sperm quality and hormone levels, making it harder to have children. Weight loss through diet and exercise helps, but it's often hard to stick with.
- Trial name
- NCT07179120
- Testing
- Semaglutide (Rybelsus®), Tirzepatide, Standardized Lifestyle Intervention
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Male Infertility With Severe Oligo-terato-asteno-spermia
Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.
Some animal studies revealed that the pomegranate juice may improve sperm quality in terms of concentration, motility and morphology, as well as in fertilization rate. Minor data is available regarding the influence on male sperm.
- Trial name
- Pomegranate (NCT01918163)
- Testing
- Pomegranate pills
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility
Food Intake Among Women and Men in Fertility Treatment
Worldwide infertility is highly prevalent and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment.
- Trial name
- Food&Fertility (NCT05454046)
- Testing
- Food intake among women and men in fertility treatment
- Where
- 8 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Aalborg University Hospital
Sperm Motility (Focus of Study)
Influence of Ribavirin and Interferon on Semen Quality, IRIS Study
The aim of this study is to study the effect of peginterferon alpha and ribavirin on spermatozoa.
- Trial name
- IRIS (NCT00455832)
- Testing
- peginterferon alpha and ribavirin
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Foundation for Liver Research
Male Infertility, Oligoasthenospermia
Investigation of the Effects of Stem Cell Supportive Treatment on Semen Parameters and Assisted Reproductive Techniques (ICSI) in Infertile Male Patients With Oligoasthenospermia(Decrease Sperm Number and Quality)
This study evaluated whether Stemregen® dietary supplementation could improve sperm quality and assisted reproductive treatment outcomes in men with severe oligoasthenozoospermia who had previously experienced at least one failed…
- Trial name
- STEMRN (NCT07800052)
- Testing
- Stemregen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Fibromyalgia
The Effect of Cherry Seed Pillow on Fibromyalgia
In this study, the effects of 4-week Cherry seed pillow application on pain and quality of life in individuals diagnosed with fibromyalgia will be examined.
- Trial name
- NCT06171022
- Testing
- Cherry seed pillow, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hasan Gerçek
Sleep Quality, Menopause
Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women
The goal of this clinical trial is to learn if ZenRest™ (Lotus Seed \& Rice Germ Extract Blend) can help improve sleep quality in menopausal women aged 40-65 with mild-to-moderate sleep complaints.
- Trial name
- NCT07678359
- Testing
- Lotus Seed & Rice Germ Extract
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Semen Quality
A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function
The goal of this clinical trial is to evaluate three doses of the drug leflutrozole on improvement of semen quality in men. It will also study the safety of leflutrozole.
- Trial name
- ETNA (NCT06993155)
- Testing
- Leflutrozole, Dose 1, Leflutrozole, Dose 2, Leflutrozole, Dose 3
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- ReproNovo Aps
Prostate Cancer
US-CT Fusion for Post Implant Dosimetry
Post implant dosimetry is an essential part of quality assurance after permanent seed prostate brachytherapy. CT imaging is the standard of assessment but due to contouring uncertainties, MR-CT fusion is preferred.
- Trial name
- NCT03692104
- Testing
- transrectal ultrasound
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- British Columbia Cancer Agency
Memory Disorders, Anxiety Depression
Coriandrum Sativum Seeds Improve Memory, Alleviate Anxiety and Depression, and Enhance Sleep Quality in University Students: A Randomized Controlled Trial
C. sativum could potentially serve as a memory enhancer for university students. It is considered a preferable option to stimulant drugs due to its safety profile. Additionally, C.
- Conditions
- Memory Disorders, Anxiety Depression, Sleep
- Trial name
- NCT05999071
- Testing
- Coriandrum sativum seeds
- Where
- Jordan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Oligoasthenoteratozoospermia, Male Infertility
Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility
Objective of the study is to compare the efficacy of tamoxifen alone \& tamoxifen with antioxidant on semen quality of infertile male with abnormal parameters (sperm count, motility, vitality, morphology) .Infertility is defines…
- Trial name
- NCT05200663
- Testing
- Tab Tamoxifen 10 mg, Tab Tamoxifen 10mg,Cap vitamin E 400mg
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Male Idiopathic Infertility
A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)
The primary purpose of this trial is to investigate whether men with idiopathic infertility (unexplained reduction of semen quality), after being treated with a daily dose of 12 µg recombinant follicle stimulating hormone (rFSH)…
- Trial name
- NCT05403476
- Testing
- FE 999049
- Where
- 22 sites in United States, Belgium and 5 more
- Volunteers
- 4 people
- Sponsor
- Ferring Pharmaceuticals
Sexual Abstinence
Influence of Physical Exercise on Semen Quality
Our study addresses a previously selected population or by physical activity but not for semen quality semen donor candidates donation program within the clinic.
- Trial name
- NCT02683057
- Testing
- International Physical Activity Questionnaire (IPAQ)
- Where
- Spain
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- IVI Bilbao
Fertility Disorders
Effects of Lifestyle Changes on Semen Quality in Healthy Young Men Living in Highly Polluted Areas (FAST)
We planned a randomized controlled trial (RCT) with the main aim to evaluate the effects of lifestyle changes on semen quality in healthy young men living in polluted areas in Italy.
- Trial name
- FAST (NCT04012385)
- Testing
- lifestyle counseling
- Where
- 4 sites in Italy
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Salerno
Infertility, Male
FITMI - First In Treating Male Infertility
This RCT aims to assess whether treatment with Denosumab can improve semen quality in infertile men selected by serum AMH as a positive predictive biomarker.
- Trial name
- NCT05212337
- Testing
- Denosumab, Sodium chloride
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Martin Blomberg Jensen