Clinical trials: Senile Cataract
Cataract
Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts
To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.
- Trial name
- NCT02895074
- Testing
- Femtosecond laser-assisted cataract surgery, Conventional phacoemulsification cataract surgery, Tropicamide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Age Related Cataracts
A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract
This is a multicenter, randomized, double-masked, placebo-controlled pilot study conducted in the United States (US) in subjects with age-related cataract in one or both eyes.
- Trial name
- NCT07395986
- Testing
- 0.4% ZOC2017217, Control
- Where
- 21 sites in United States
- Volunteers
- 8 people
- Sponsor
- Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd.
Cataract Senile
The Effect of LASIK on the Calibration of IOL Formula Calculation: a Comparative Study
Direct comparison study between previous LASIK or non-LASIK cataract eyes, the performance between non-LASIK and LASIK patients were (i) Ophthalmic examinations: UDVA, CDVA and uncorrected near visual acuity (UNVA) (40cm) and…
- Trial name
- NCT06165796
- Testing
- routine cataract surgery and intraocular lens implantation
- Where
- Taiwan
- Volunteers
- 331 people
- Sponsor
- Taipei Nobel Eye Clinic
Microbial Disease, Cataract Senile
Effect of Topical Besifloxacin on Ocular Surface Bacterial Microbiota Prior to Cataract Surgery
Describe the efficacy of the use of topical besifloxacin in reducing the conjunctival microbiota as a prophylactic measure in patients scheduled for cataract surgery.
- Trial name
- NCT04542759
- Testing
- Besifloxacin Ophthalmic, Hydroxypropyl Methylcellulose Ophthalmic Ophthalmic Solution
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Cataract Senile
Project Bidof - Monovision by Pairing Bifocal and EDOF Lens
Modern day cataract surgery isn't just a rehabilitative procedure anymore but rather aims at improving a patient's quality of life by reducing the need for spectacles in everyday life to a minimum.
- Trial name
- Bidof (NCT05303571)
- Where
- Austria
- Sponsor
- Johannes Kepler University of Linz
Cataract Senile
Prospective Clinical Study of Preoperative and Postoperative Unilateral Mild Cataract Patients
This is to compare preoperative and postoperative binocular functional vision in patients with unilateral intraocular len（IOL） in one eye and mild cataract in the fellow eye.
- Trial name
- NCT04266847
- Testing
- monofocal IOL,bifocal IOL,or trifocal IOL
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Age Related Cataracts, Cystoid Macular Edema
Evaluation of Central Macular Thickness in Femtosecond Laser-assisted Cataract Surgery
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure.
- Trial name
- FLAME (NCT03465124)
- Testing
- Femtosecond Laser, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cataract
Phaco Versus Small Incision Cataract Surgery (SICS) Health Economic Study
To compare the health economic parameter and clinical outcome of Phacoemulsification with small incision cataract surgery (SICS)
- Trial name
- NCT00762606
- Testing
- Phacoemulsification cataract extraction surgery, Small incision cataract surgery
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Alcon Research
Cataract Senile, Astigmatism
Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
In cataract surgery, the opaque lens is replaced by an artificial intraocular lens. The procedure also allows for correction of an refractive error such as myopia, hyperopia or astigmatism.
- Trial name
- NCT05750862
- Testing
- Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Frank Bochmann
Cataract Senile
Comparison Between Two Ss-OCT Biometry
Since recently a second swept-source optical coherence tomography (ss-OCT) optical biometry device was launched (Anterion, Heidelberg Engineering).
- Trial name
- NCT04333056
- Testing
- Biometric measurement agreement
- Where
- Austria
- Volunteers
- 210 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Diabetes Mellitus Type 2, Age Related Cataracts
Comparison of Retinal Perfusion Between Diabetic and Non-diabetic Patients With OCT Angiography After Cataract Surgery.
This study aims to compare the retinal perfusion between diabetic and non-diabetic patients with Optical Coherence Tomography（OCT） Angiography after cataract surgery, to thoroughly evaluate the retinal state of diabetics after…
- Trial name
- NCT03903965
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Cataract
Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)
The Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) is a 13-year study designed primarily to evaluate the safety and efficacy of a vitamin-mineral supplement (Centrum)…
- Trial name
- CTNS (NCT00309387)
- Testing
- Centrum
- Where
- Italy
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)