Clinical trials: Sensation Disorders
Tinnitus, Sleep Disturbances
Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
Background: Tinnitus, as a common symptom, can jeopardize the sleep quality and brain function and even lead to hearing loss and cognitive decline in elderly patients.
- Conditions
- Tinnitus, Sleep Disturbances, Cognition
- Trial name
- NCT06776705
- Testing
- Low-intensity transcranial ultrasound stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong
Hearing Loss
Antioxidation Medication for Noise-induced Hearing Loss
This study will examine whether oral intake of 1200mg N-Acetylcysteine/day will prevent temporary threshold shift in hearing among workers exposed to noise
- Trial name
- NCT00552786
- Testing
- N-acetylcysteine (NAC), glucose
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anosmia
Does Cardiopulmonary Bypass Change Olfaction?
The loss of the sense of smell, anosmia, can have profound effects on the lives of those who suffer from it. In our clinical practice, we have encountered several patients complaining of anosmia after recently undergoing surgery…
- Trial name
- Anosmia (NCT02179554)
- Where
- United Kingdom
- Sponsor
- Manchester University NHS Foundation Trust
Neuro Developmental Delay, Sensory Disorders
Aquatic Therapy Versus Sensory Room Intervention for Sensory-Motor Function in Children With Sensory Processing Disorder
This randomized clinical trial compares the effects of aquatic therapy and conventional sensory room intervention on adaptive neural responses and sensory-motor praxis in children with Monochannel Sensory Processing Disorder.
- Trial name
- AQUA vs SRI Tr (NCT07646951)
- Testing
- Aquatic Therapy
- Volunteers
- 60 people
- Sponsor
- MTI University
Smell Disorders
Efficacy and Safety of Phototherapy in the Treatment of Loss of Smell Post Acute Infection of Coronavirus 19
The aim of this study is to assess whether the use of a therapy combining olfactory training, corticoids, and phototherapy improves the PROMS compared to the use of olfactory training and corticosteroids only.
- Trial name
- NCT05177445
- Testing
- Phototherapy, OT+Corticosteroids
- Where
- Ecuador
- Volunteers
- 40 people
- Sponsor
- Respiralab
COVID-19
Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)
Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory…
- Trial name
- COVID-OLFA (NCT04407494)
- Testing
- Reporting of anosmia, ageusia and other clinical symptoms
- Where
- France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
BPPV
Efficacy of a New Type of Mechanical Rotational Chair in Treating BPPV
A study to establish the efficacy of a new type of mechanical rotational chair in treating BPPV. In addition, comparison of three types of treatment maneuvers using the mechanical rotational chair.
- Trial name
- NCT04147156
- Testing
- Epley's Maneuver, Semont Maneuver, 360 degree vertical rotation
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aalborg University Hospital
Hearing Loss
Optimisation of Hybrid Fittings for Cochlear Implant Recipients
When providing amplification post-implantation to residual acoustic hearing in the implanted ear, the lower frequency boundary can be modified to minimize or avoid overlap between the frequencies coded through acoustic hearing…
- Trial name
- NCT02765386
- Testing
- Hybrid fittings for cochlear implant recipients
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- The Hearing Cooperative Research Centre
Tinnitus, Subjective
The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus
The goal of this study is to evaluate the effect of 4-7-8 breathing exercise on tinnitus handicap, psychological factors and sleep quality.
- Trial name
- NCT06360731
- Testing
- 4-7-8 breathing exercise technique and informative session on tinnitus, Informative session on tinnitus
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ege University
Hearing Loss
Telemonitoring in Cochlear Implant Patient Care
Following a sufficient delay after the cochlear implantation and initial implant activation, the patient will return to the hospital for follow-up visits for equipment maintenance and auditory performance evaluation only once per…
- Trial name
- EMPSICOT (NCT05566353)
- Testing
- Remote Check
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Montpellier
Wolfram Syndrome 1, Optic Atrophies, Hereditary
Does Recessive Optic Atrophy Due to WFS1 Exist?
All patients with Wolfram syndrome and recessive optic atrophy due to a mutation of the WFS1 from a single Center were included in a retrospective study.
- Trial name
- NCT07336966
- Testing
- analyse study
- Volunteers
- 45 people
- Sponsor
- Hôpital Necker-Enfants Malades
Electroacupuncture, Noise Induced Hearing Loss
The Effect of Acupuncture on Patients With Noise-induced Hearing Loss
In an era of advanced industry and commerce, working in a noisy environment is one of the most important risk factors for hearing damage, especially among young and middle-aged people.
- Conditions
- Electroacupuncture, Noise Induced Hearing Loss, Hearing Loss, Noise-Induced
- Trial name
- NCT05511753
- Testing
- electroacupuncture
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Tinnitus
A Randomized Controlled HD-tDCS Trial: Effects on Tinnitus Severity and Cognition
This randomized, placebo-controlled study will compare the effects of HD-tDCS (a non-invasive neuromodulation technique) with a sham stimulation.
- Trial name
- NCT03754127
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 81 people
- Sponsor
- University Hospital, Antwerp
Hyperalgesia, Chronic Pain Syndrome
Pain-related Fear as a Facilitator of Nocebo Hyperalgesia
Nocebo hyperalgesia is characterized by adverse pain outcomes, induced by patients' expectations. In the lab, nocebo effects are commonly studied via classical conditioning, a method that employs pairings of neutral…
- Conditions
- Hyperalgesia, Chronic Pain Syndrome, Chronic Pain, Psychogenic, Fear of Pain
- Trial name
- LFS (NCT04197154)
- Testing
- Threat manipulation (control, no threat), Threat manipulation, Conditioning of moderate pain
- Where
- Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Chronic Venous Disease, Chronic Venous Insufficiency, CVI
The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry
The goal of this observational study is to gather additional safety and performance (effectiveness) data on the device for the treatment of symptomatic lower extremity venous obstructions and occlusions.
- Conditions
- Chronic Venous Disease, Chronic Venous Insufficiency, CVI, Venous Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- CALIBER (NCT07529756)
- Testing
- Recanalization and debulking
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Intervene, Inc.
CHARGE Syndrome
Neurovisual Function in CHARGE Syndrome
The rationale of the study is to analyze visual function and correlate them with adaptive functions in patients with CHARGE syndrome in order to identify a pattern of specific indicators to enable better patient care
- Trial name
- NCT05764980
- Testing
- visual function evaluation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Eye Diseases, Vision Disorders
Determination of the Validity of a Questionnaire to Assess the Visual Function of Preverbal Children With Operable Bilateral Ocular Pathologies
In some symmetrical pediatric ocular pathologies, the treatment is surgical with usually satisfactory postoperative results in visual terms. However, it is often difficult to choose the right moment to operate.
- Trial name
- EVEIL (NCT04428541)
- Testing
- Questionnaire for visual function assessment of preverbal children
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Anesthesia, Epidural, Paraesthesia
Safety of Two Epidural Catheters in Thoracic Epidural Anaesthesia (TEA)
Primary Objective: The primary objective is to demonstrate that the safety of Perifix New is non-inferior to using Perifix Standard when applied for thoracic epidural anaesthesia.
- Trial name
- NCT00394459
- Testing
- Perifix Epidural Anaesthesia Catheter, Perifix Standard, Perifix New
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Maastricht University Medical Center
Hearing Impairment, Deafness
Extended Reality Vocational Training for Hearing Impaired
This study examines the efficacy of an interactive, extended reality (XR)-based virtual training environment-specifically utilizing 360-degree virtual reality (360-VR) interactive simulations-against conventional vocational…
- Trial name
- NCT07639346
- Testing
- Interactive 360-degree Virtual Reality Vocational Training
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- King Salman Center for Disability Research