Clinical trials: Sensation Disorders, open to volunteers
Anosmia
Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19
One of the most widespread symptoms of COVID-19 is loss of the sense of smell. There are very few treatments for helping individuals recover their sense of smell.
- Trial name
- NCT06766279
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Burrell College of Health Sciences
Pulsatile Tinnitus, Venous Sinus Stenosis
BosSTENT ImpLant to trEat debilitatiNg Pulse-synchronous Tinnitus
This study is evaluating the safety and clinical performance of the BosSTENT, a new stent designed specifically for treating pulse-synchronous tinnitus due to venous sinus stenosis.
- Trial name
- B-SILENT (NCT07070089)
- Testing
- BosSTENT implantation
- Where
- 6 sites in Canada, France
- Volunteers
- 90 people
- Sponsor
- Sonorous NV, Inc
Hearing Disorders and Deafness
ListenFuture-Listening for Their Future: Deaf and Hard-of-Hearing Adolescents
ListenFuture, a nation-wide multidisciplinary project, brings new knowledge on complex associations between listening, cognition, language, literacy, and psychosocial wellbeing in deaf and hard-of-hearing (DHH) adolescents.
- Trial name
- ListenFuture (NCT07416292)
- Where
- 7 sites in Finland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Heikki Löppönen
Cochlear Implant, Sensorineural Hearing Loss
The Effect of Anatomy-based Fitting on the Perception of Speech in Noise and Music in Single-sided Deaf Cochlear Implant Users
The present study evaluates the effect of anatomy-based fitting on speech perception in noise and music perception in newly implanted single-sided deaf (SSD) CI recipients.
- Conditions
- Cochlear Implant, Sensorineural Hearing Loss, Single Sided Deafness
- Trial name
- NCT07703800
- Testing
- Anatomy-based fitting, Default fitting
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Age-related Hearing Loss, Hearing Loss, Sensorineural
Comparing the Efficacy of Domestic Versus Imported Hearing Aids in ARHL
This study compares the hearing improvement effects of domestic hearing aids and imported hearing aids in 80 patients with moderate to severe and severe age-related hearing loss.
- Trial name
- NCT06882889
- Testing
- Domestic hearing aids, Imported hearing aids
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Usher Syndromes
Natural History Study of Usher Syndrome ( Light4Deaf )
Clinical centres in the LIGHT4DEAF consortium have developed and will continue to improve a reliable, early molecular diagnosis and protocols for full clinical characterisation of Usher syndrome, which will be valuable for the…
- Trial name
- Light4Deaf (NCT04665726)
- Where
- 4 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Respiratory Tract Infection, Smell Disorder
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
Background: Loss of the sense of smell can seriously affect a person's quality of life. The ability to smell can be damaged by many factors, including illnesses, injuries, and exposure to toxic chemicals.
- Conditions
- Respiratory Tract Infection, Smell Disorder, Influenza, Rhinosinusitis
- Trial name
- NCT07149428
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
SCHIZOPHRENIA 1 (Disorder), Sensory Perceptual Characteristics
Precision HD-tACS for Enhancing Sensory Experience in Schizophrenia
To ensure unified sensory perception, the brain must link information from different senses across time and space. This unification of perception often referred to as a perceptual "binding constraint" is a prerequisite for any…
- Trial name
- TherACles (NCT07632261)
- Testing
- Transcranial neurostimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Amblyopia
Binocular Visual Therapy and Video Games for Amblyopia Treatment.
Amblyopia, or lazy eye, is best defined by the American Academy of Ophthalmology as a unilateral or bilateral reduction of the best corrected visual acuity that occurs in the setting of an otherwise normal eye, or a structural…
- Trial name
- NCT03655912
- Testing
- Red/green glasses, Electronic Tablet, Eye patch
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Pulsatile Tinnitus
Dural Sinus Stenting of Low Grade Dural Arteriovenous Fistulae (DAVF) for Pulsatile Tinnitus Treatment
The goal of this randomized trial to assess the angiographic efficacy of venous stenting in dural arteriovenous fistulae (DAVF) via improvment on Cognard's Classification as compared to no intervention at 6 months Participants…
- Trial name
- INVENT (NCT05679271)
- Testing
- Venous stenting, Standard of care
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bordeaux
Suicidal Ideation, Eating Disorder Symptom
Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional…
- Trial name
- RISE (NCT05285111)
- Testing
- Reconnecting to Internal Sensations and Experiences, Healthy Habits
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Auburn University
Hearing Disorder
Evaluation of Cochlear (Promontory) Stimulation During Awake Ear Surgery (TONES Study)
The goal of this clinical trial is to learn if short electrical signals can be heard in adult subjects who are otherwise having surgery on their ear.
- Trial name
- NCT07402941
- Testing
- Electrical extracochlear stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Auricle Health Inc.
Hearing Aids, Hearing Loss, Bilateral Sensorineural
Effectiveness Comparison of 3D-Printed and Conventional Ear Tip Comfort in Individuals With Hearing Loss
Access to affordable and timely hearing healthcare remains a major challenge for many individuals, partly due to the high cost and long turnaround time.
- Conditions
- Hearing Aids, Hearing Loss, Bilateral Sensorineural, 3D Printing
- Trial name
- NCT07228845
- Testing
- BTE hearing aids with compatible ear tips (Third-party, FlexResin, Resin), BTE hearing aids with compatible ear tips (FlexResin, Resin, Third-party, FlexResin), BTE hearing aids with compatible ear tips (Resin, Third-party, FlexRes)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Arizona
Deafness
Novel Coding Strategies for Children With Cochlear Implants
The purpose of this study is to understand performance with a cochlear implant. The long-term goals of this research are to improve sound perception with cochlear implants and to better understand the functioning of the auditory…
- Trial name
- NCT05203302
- Testing
- Single-Electrode Pulse Train, Modulation Detection Threshold (MDT) and Gap Detection Tasks, Sound coding strategy.
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tinnitus, Chronic Subjective Tinnitus
Acute Nicotine Gum and Auditory Brain Responses in Adults With Chronic Tinnitus
This study tests whether a single dose of nicotine gum changes brain responses to sounds and the ability to detect target sounds in non-smoking adults with chronic tinnitus.
- Trial name
- NCT07877701
- Testing
- Nicotine polacrilex gum 4 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Xianhui Wang
Obesity/Therapy
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Glucagon-like peptide 1 receptor agonists (GLP-1RA), such as Ozempic and Wegovy, have been rapidly adopted for the treatment of obesity in both youth and adults.
- Trial name
- PLASTIC (NCT07021937)
- Testing
- Semaglutide 1.7mg subcutaneous
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries, Spinal Cord Injury Cervical
Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System
This is a single-cohort early feasibility trial to determine whether an investigational device called the Bidirectional Neural Bypass System can lead to the restoration of movement and sensation in the hand and wrist of up to…
- Trial name
- NCT03680872
- Testing
- Bidirectional Neural Bypass System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Chad Bouton
Motion Sickness, Somatosensory Disorders
Motion Sickness Severity and Sensorimotor Performance
Background: Motion sickness (MS) is a common syndrome characterized by autonomic and behavioral symptoms, such as nausea and dizziness, resulting from exposure to motion stimuli.
- Conditions
- Motion Sickness, Somatosensory Disorders, Dizziness
- Trial name
- NCT07619469
- Testing
- Standardized Sensorimotor Assessment and Motion Sickness Provocation Protocol
- Volunteers
- 41 people
- Sponsor
- Istinye University
Dental Pain and Sensation Disorder, Pain, Postoperative
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing…
- Trial name
- NCT04860141
- Testing
- Gabapentin 600mg
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Hearing Loss, Head and Neck Cancer
Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol.
- Trial name
- NCT04915183
- Testing
- Atorvastatin
- Where
- 5 sites in United States
- Volunteers
- 224 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)