Clinical trials: Sensitisation
- Condition Sensitisation
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Sensitivity, Contact
Sensitization Study of ATx201 in Healthy Volunteers
This is a Phase I, single-site study to evaluate the sensitization potential of topically applied ATx201 GEL, 2% and 4%, along with a placebo control, in healthy human subjects.
- Trial name
- NCT03375957
- Testing
- ATx201
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- UNION therapeutics
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of 1 Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of 1 topically applied test article containing Mitopure in a shared panel of healthy volunteers by means of repeated cutaneous patch…
- Trial name
- GLOW-Safety-4 (NCT07517874)
- Testing
- Mitopure Topical Formula 11
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Cumulative Irritation and Sensitization
Study Will Assess Skin Irritation and Sensitization for HP-1050 Patch
A randomized, evaluator-blinded study to assess skin irritation and skin sensitization of HP-1050 transdermal system (HP-1050) in comparison to XULANE patch in healthy female volunteers.
- Trial name
- NCT04624867
- Testing
- HP-1050 Patch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Noven Pharmaceuticals, Inc.
Pain, Esophageal Sensitivity
Esophageal Hypersensitivity Study in Healthy Volunteers
The purpose of the study is to compare sensitivity and sensitization of visceral pain in the esophagus using different pain stimuli
- Trial name
- NCT00711048
- Testing
- AZD1386
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Tendinopathy
A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers
This is a single center, randomized, controlled, within subject comparison, single dose study to determine the sensitization potential of SM04755 solution on normal skin under semi-occlusive patch conditions.
- Trial name
- NCT03502434
- Testing
- SM04755, Vehicle, White Petrolatum
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Biosplice Therapeutics, Inc.
Menopause, Healthy Female Participants
A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects
The two products used in this study are transdermal patches that contain selegiline. The test drug is the Estradiol/Levonorgestrel Transdermal Delivery System (TDS). The comparator drug is the Climara Pro® TDS.
- Trial name
- NCT07794150
- Testing
- Estradiol/Levonorgestrel Transdermal System
- Where
- 2 sites in United States, India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Skin Care
Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage
The investigational product constitutes a medical device that is freely accessible to consumers and, as such, must be safe under real or reasonably foreseeable conditions of use and its safety must be tested before being placed…
- Trial name
- NCT05876546
- Testing
- Liquid bandage, Saline Solution
- Where
- 2 sites in Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated and Sensitization
This is a clinical study for health care product safety assessment. The research will be conducted with 92 subjects, aged 18 to 59 years.
- Trial name
- NCT04248556
- Testing
- Health care product
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Major Depressive Disorder (MDD)
A Study to Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects
The two products used in this study are transdermal patches that contain selegiline. The test drug is the Selegiline Transdermal Delivery System (TDS). The comparator drug is the EMSAM® TDS.
- Trial name
- NCT07452692
- Testing
- Selegiline Transdermal Delivery System
- Where
- 3 sites in Bulgaria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Skin Sensitisation
Skin Sensitization Test (Modified Draize-95 Test)
Skin Sensitization Test (Modified Draize-95) to Support a Low Dermatitis Potential Claim for a Blue Non Sterile Powder Free Nitrile Examination Gloves.
- Trial name
- Draize-95 (NCT04274647)
- Testing
- NON-STERILE, POWDER FREE NITRILE EXAMINATION GLOVES, LOW DERMATITIS POTENTIAL, TESTED FOR USE WITH CHEMOTHERAPY DRUGS - BLUE
- Where
- Malaysia
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- YTY Industry (Manjung) Sdn Bhd
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety (NCT05079607)
- Testing
- Mitopure Topical Formula 1, Mitopure Topical Formula 2
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety-2 (NCT06884215)
- Testing
- Mitopure Topical Formula 3, Mitopure Topical Formula 4
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Sensitisation
Skin Sensitisation (Modified Draize-95 Test)
Skin Sensitization Test (Modified Draize-95) to Support a Low Dermatitis Potential Claim for a Powder Free Polychloroprene Surgical Gloves, Sterile.
- Trial name
- MDT-95 (NCT04402476)
- Testing
- Powder Free Polychloroprene Surgical Gloves, Sterile. Low Dermatitis Potential, tested for use with Chemotherapy drugs.
- Where
- Malaysia
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- PT. Medisafe Technologies
Sensitivity, Contact
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Phototoxicity.
This is a clinical study for health care product safety assessment. The research is going to conducted with 55 subjects, aged 18 to 70 years. The product is applied on the right and/or left participant back.
- Trial name
- NCT04332445
- Testing
- Hyaluronic Acid Gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Hypersensitivity
Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test)
In this study researcher want to learn more about possible skin reactions such after repeated application of an antifungal cream containing Trolamine. They are especially interested in skin irritations or allergic skin reactions.
- Trial name
- NCT04531540
- Testing
- Butenafine HCl 1% (BAY1896425)
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Bayer
Skin Irritation
Patch Test Skin Irritation/Sensitization of Cetaphil Daily Facial Moisturizer SPF 50
Determine if Cetaphil Daily Facial Moisturizer SPF 50 proves to be a contact sensitizer or irritant in certain individuals.
- Trial name
- NCT01887860
- Testing
- Cetaphil Daily Facial Moisturizer SPF 50
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Irritation
Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Dermacontrol Oil Control Moisturizer SPF 30
Determine if Cetaphil DermaControl Oil Control Moisturizer SPF 30 proves to be a contact sensitizer or irritant in certain individuals
- Trial name
- NCT01887808
- Testing
- Cetaphil DermaControl Oil Control Moisturizer SPF 30
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Sensitization
Human Repeat Insult Patch Test of Wound Dressings
The purpose of this study is to determine whether contact sensitization occurs to the skin of normal healthy human subjects, by repetitive application of IV Clear™, Tegaderm CHG™ and Silicone Vehicle Control dressings.
- Trial name
- NCT01368146
- Testing
- IV Clear™, Tegaderm CHG™, Silicone Vehicle Control Dressing
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Covalon Technologies Inc.
Hyperalgesia
A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
GSK189254 is a highly potent histamine 3 (H3) receptor antagonist which has demonstrated efficacy in the reduction of mechanical hyperalgesia and allodynia in the chronic constriction injury pre-clinical model of neuropathic pain…
- Trial name
- NCT00387413
- Testing
- Duloxetine, GSK189254
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteers
Contact Sensitization Potential of 828 Ointment
Contact sensitization by patch applications.
- Trial name
- NCT00767676
- Testing
- HP828-101
- Where
- United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Healthpoint