Clinical trials: Sensorineural Hearing Loss (Disorder)
Hearing Loss, Cochlear, Neurinoma of the Acoustic Nerve
Auditory Nerve Monitoring Using Intra-cochlear Stimulation in Subjects With Acoustic Neuroma
The aim of this study is to assess the auditory nerve functionality with an intraoperative approach following a surgical removal of acoustic neuroma in patients with severe to profound sensorineural hearing disabilities.
- Trial name
- NeuriStim (NCT02948790)
- Testing
- Neuristim, Cochlear implant
- Where
- 4 sites in France
- Volunteers
- 17 people
- Sponsor
- Oticon Medical
Conductive Hearing Loss, Mixed Hearing Loss
Evaluation of a Hearing Device for Transmitting Sound to the Inner Ear
A single center study evaluating the performance of an externally worn sound processor for a transcutaneous bone anchored hearing system using audiological outcomes measures such as aided thresholds and self-evaluation…
- Trial name
- NCT05628285
- Testing
- Sentio 1
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Oticon Medical
Sensorineural Hearing Loss, Low-Frequency Residual Hearing
Hearing Implant Performance in Adults With Low-Frequency Residual Hearing
The purpose of the feasibility study is to investigate hearing performance (audiometry and speech perception) using the CI624 in a group of adults (n=15) with low-frequency residual hearing who meet inclusion criteria.
- Trial name
- NCT04741048
- Testing
- CI624 Slim 20 Electrode
- Where
- United States
- Sponsor
- Cochlear
Presbycusis, Bilateral
Impact of Hearing Aid Technology on Self-reported Outcomes
The study aims to investigate if the level of hearing aid (HA) technology has an impact on self-reported outcomes in patients with presbycusis in terms of overall IOI-HA scores, Factor 1, Factor 2 scores, SSQ scores, and the SSQ…
- Trial name
- NCT04539847
- Testing
- High-end hearing aid, Basic hearing aid
- Volunteers
- 208 people
- Sponsor
- University of Southern Denmark
Hearing Impairment, Sensorineural
CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology
This clinical study aims to investigate speech performance in quiet with an OTE Sound Processor with modified firmware compared with the commercially available CP1150.
- Trial name
- NCT05286385
- Testing
- CP1150 Sound Processor, CP1150 NF, CP1150 + FF
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Cochlear
Hearing Loss, Sensorineural Hearing Loss
Quality Control of CE-Certified Phonak Hearing Aids - 2019_19
Phonak Hearing Systems pass through different development and study stages. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner.
- Trial name
- NCT03992989
- Testing
- Phonak Bolero M90-M, Roger Select
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Hearing Loss, Conductive, Hearing Loss Mixed
Investigating Hearing With Ponto 3 SuperPower, a Bone Anchored Hearing Aid - Investigating Hear
The study is part of the Post Market Clinical Follow (PMCF) activity. The investigational device is the CE-marked Ponto 3 SuperPower (available on the market since December 2016) already fitted to the subjects, and data is…
- Conditions
- Hearing Loss, Conductive, Hearing Loss Mixed, Hearing Disability, Conductive Hearing Loss
- Trial name
- NCT04803279
- Testing
- Collection of Pure tone thresholds from audiogram measured prior to fitting of Ponto 3 SuperPower, Collection of BC In-situ thresholds from BC In-situ audiogram measured during fitting of Ponto 3 SuperPower, Collection of Aided sound field thresholds measured with the Ponto 3 SuperPower
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Oticon Medical
Hearing Loss, Sensorineural
Evaluation of an Open-source Speech-processing Platform
Determining acceptability and usability of a wearable open-source speech processing platform (Master Hearing Aid) developed for hearing-aid research
- Trial name
- EOSP (NCT03686046)
- Testing
- Exploratory use
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Bilateral Sensorineural Hearing Loss, Unilateral Sensorineural Hearing Loss
Pupillometry Techniques Usage to Quantify the Programming Parameters Effect in the Auditory Effort in Zti Opticon Cochlear Implant Adult Users
The aim of this study is to establish the connection between the cochlear implant programming parameters with the auditory effort associated with the speech perception evaluated by pupillometry techniques in different audiometric…
- Trial name
- NCT05300230
- Testing
- Neuro Zti cochlear implant and Neuro 2 sound processor
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Mixed Hearing Loss, Single-Sided Deafness
Osia 2 Pediatric Expansion Study
The CochlearTM Osia®2 System was cleared by the Food and Drug Administration November 15, 2019 (K191921) for individuals aged 12 years and older who present with conductive or mixed hearing loss (up to 55 dB HL) or…
- Conditions
- Mixed Hearing Loss, Single-Sided Deafness, Conductive Hearing Loss
- Trial name
- NCT05000931
- Testing
- Osia 2 System
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cochlear
Dementia, Hearing Loss
Evaluation of the Impact of Cochlear Implants on Cognition in Older Adults
The subjects will be age 65 years and older, with no upper limit of age range with hearing loss that are candidates for standard-of-care cochlear implant.
- Conditions
- Dementia, Hearing Loss, Presbycusis
- Trial name
- NCT02729402
- Testing
- Cognitive Testing
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hearing Loss
Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System
The aim of this clinical investigation is to collect data on objective and subjective hearing performance, quality of life and safety in adult subjects with conductive hearing loss, mixed hearing loss or single-sided…
- Trial name
- NCT04041700
- Testing
- Osia 2 system
- Where
- 3 sites in Australia, Hong Kong
- Volunteers
- 29 people
- Sponsor
- Cochlear
Hearing Loss, Bilateral Sensorineural
Cochlear Implantation and Social Outcomes
The goal of this clinical trial is to learn if hearing devices, like cochlear implants, affect social and cognitive function of older adults.
- Trial name
- NCT07584837
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Age-related Hearing Loss
First Clinical Study to Evaluate Safety, Tolerability & PK of DX243 in Healthy Volunteers and Patients With Hearing Loss
Phase 2a: Multiple Ascending Dose (MAD) in male and female patients with hearing loss: The study will be conducted according to a randomised, placebo-controlled, double-blind design.
- Trial name
- DX243-101 (NCT07637981)
- Testing
- DX243
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Dendrogenix
Hearing Loss, Sensorineural
Training Language and Literacy for Children Who Use CIs
This study aims to determine the effectiveness of computer games to improve language and literacy outcomes for children who have hearing loss.
- Trial name
- NCT03582566
- Testing
- Phonological Awareness, Working Memory, Phonological Awareness + Working Memory
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Florida State University
Hearing Loss, Sensorineural, Cochlear Hearing Loss
Neuro 1 vs. Neuro 2 Sound Processors
This study evaluates the benefit of Neuro 1 sound processor upgrade in speech perfomance in adults. Half of participants will be tested with Neuro 1 first and Neuro 2, while the other half will be tested with Neuro 2 first and…
- Trial name
- NCT03756337
- Testing
- Neuro 1 & Neuro 2, Neuro 2 & Neuro 1
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Oticon Medical
Sensorineural Hearing Loss
Autologous Bone Marrow Harvest and Transplant for Sensorineural Hearing Loss
Autologous human bone marrow mononuclear fraction (BMMF) will be harvested and given to children with bilateral moderate to severe sensorineural hearing loss.
- Trial name
- NCT02616172
- Testing
- Autologous Bone Marrow Infusion
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- James Baumgartner, MD
Sudden Loss of Hearing
Bed Rest for Idiopathic Sudden Sensorineural Hearing Loss
sudden sensorineural hearing loss: idiopathic in most cases 5-20/100,000 new cases annually in the U.S no establishes pathogenesis treated with oral steroids in most cases ~50% improvement in hearing levels bed rest - acceptable…
- Trial name
- NCT00416143
- Testing
- bed rest, prednisone - oral corticosteroid 1mg/kg/D for 1 week
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Hearing Loss, Sensorineural
Hearing Aid Processing and Working Memory in Realistic Spatial Conditions
The goal of this project is to determine whether the selection of hearing aid settings should be based in part on an individual's cognitive characteristics (specifically, working memory).
- Trial name
- DIRWDRCWM (NCT04521166)
- Testing
- Hearing aid
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction
Hearing/ET/Vestibular in Balloon Pilots
This study looks at whether working as a hot-air balloon pilot-being exposed to burner noise, changes in air pressure/temperature, and vertical acceleration-is linked to changes in hearing, Eustachian tube function, and…
- Conditions
- Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction, Vestibular Disorders, Occupational Exposure
- Trial name
- FLIGHT-EAR (NCT07200310)
- Testing
- Non-invasive audiologic and vestibular assessments
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital