Clinical trials: Sensory Disorder
Melanoma (Skin)
Real-life Pharmacological Monitoring of Encorafenib-Binimetinib in the Treatment of Metastatic Melanoma
In recent years, the prognosis for BRAFV600E-mutant metastatic melanoma has been transformed with targeted therapies combining BRAF and MEK inhibitors (dabrafenib-trametinib and encorafenib-cobimetinib), which have improved…
- Trial name
- SPEBINI (NCT06774989)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain, Breast Surgery
Injection Rate and Erector Spinae Plane Block
To evaluate the effect of injection rate on the block sensory level in the ESP block.
- Trial name
- NCT04895072
- Testing
- Standard group, Long group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Stroke
Transcranial Direct Current Stimulation Combined Sensory Modulation Intervention in Chronic Stroke Patients
Background and purpose: About 30% of people with stroke suffered from severe long-term upper extremity （UE） motor impairment. Severe UE impairment, especially dysfunction of hand, can greatly impact stroke patients' daily living…
- Trial name
- NCT01847157
- Testing
- tDCS, Epidermis anesthesia, Repeated passive movement
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Diabetic Polyneuropathy, Peripheral Nervous System Diseases
The Effect of Oral DLBS1033 in Patients With Diabetic Polyneuropathy
This study aims to evaluate whether oral DLBS1033 can improve clinical symptoms and biological markers of nerve damage in adults with diabetic polyneuropathy.
- Conditions
- Diabetic Polyneuropathy, Peripheral Nervous System Diseases, Peripheral Neuropathy, Diabetes Mellitus
- Trial name
- NCT07475065
- Testing
- DLBS1033
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Sebelas Maret
Prostatic Neoplasms
Prevalence of HRR-related Genes Mutations and Prognosis in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients in Real World Setting
The purpose of this study is to investigate the prevalence of tissue homologous recombination repair (HRR)-related gene mutations (positive/negative/Variant of uncertain significance (VUS)), clinical outcome such as…
- Trial name
- ZENSHIN (NCT04425200)
- Where
- 26 sites in Japan
- Volunteers
- 205 people
- Sponsor
- AstraZeneca
Asymptomatic Apical Periodontitis, Endodontic Retreatment
Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment
This prospective, randomized, controlled, single-blind, parallel-group clinical trial evaluates whether intracanal cryotherapy reduces postoperative pain and inflammatory biomarker levels following single-visit endodontic…
- Conditions
- Asymptomatic Apical Periodontitis, Endodontic Retreatment, Cryotherapy
- Trial name
- ICE-PAIN (NCT07733700)
- Testing
- Intracanal cryotherapy, Room-temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Alanya Alaaddin Keykubat University
Stroke
Effects of Transcranial Magnetic Stimulation Associated to Sensory Therapy for Treatment of Motor Function of Upper Limb of Stroke Patients
The aim of this research will be to investigate in stroke patients whether upper limb motor function can be maximized in response to sensory stimulation by comparing protocols for the application of Transcranial Magnetic…
- Trial name
- NCT03329807
- Testing
- Transcranial Magnetic Stimulation, conventional sensory therapy
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Pernambuco
Disorder of Consciousness
Evaluation of the MuSICCA for Measuring Awareness
Prolonged Disorders Of Consciousness (PDOC) include the Vegetative State (VS) and the Minimally Conscious State (MCS) that persist for longer than four weeks.
- Trial name
- NCT04050995
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 80 people
- Sponsor
- The Children's Trust, United Kingdom
Carpal Tunnel Syndrome
Local Effects of Acupuncture and Nerve Conduction Studies
Thus study aims to characterize the local, nerve-specific effects of acupuncture on the median and ulnar nerves in the forearm, using nerve conduction studies and quantitative sensory testing.
- Trial name
- NCT03036657
- Testing
- MAC acupuncture needles, Electrostimulator 6c.Pro, Pantheon Research, Venice, CA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Disorder of Glucose Regulation
SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition
We investigate the impact of taste receptors (sweet, bitter and umami) on human metabolism. There ist growing evidence, that components of the taste signalling system, including the taste receptor proteins , have important…
- Trial name
- SEGATROM (NCT02219295)
- Testing
- sweet block, bitter block, umami-block
- Where
- Germany
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Ischemic Stroke
Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke
Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but…
- Trial name
- NCT05652751
- Testing
- nerve growth factor, physiological saline, EA
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Multiple Sclerosis
Validation of Multimodal Evoked Potentials (mmEP) for Predicting Disease Progression in Multiple Sclerosis
Utility of Multimodal Evoked potentials (mmEP) for monitoring disease course and prediction of progression at different stages of Multiple Sclerosis (MS) is investigated
- Trial name
- SMSC (NCT03632473)
- Testing
- multimodal evoked potentials (mmEP)
- Where
- 3 sites in Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Basel, Switzerland
Autism Spectrum Disorder (ASD)
Sensory-Motor Integration for Sensory Processing and Balance in ASD
This randomized controlled trial evaluates the effectiveness of a 16-week structured sensory-motor integration exercise program compared to conventional therapy (Applied Behavior Analysis and massage therapy) in improving sensory…
- Trial name
- SMIE-ASD (NCT06922422)
- Testing
- Sensory-Motor Integration Exercises, Conventional therapy group
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Assiut University
Deafness
Influence of the Sensory Profile of Deaf Children With Autism Spectrum Disorders on the Outcome of Cochlear Implantation
An unpublished study conducted at Toulouse University Hospital revealed that 30% of implanted children with Autism Spectrum Disorders abandon their implant, while 70% of them keep it.
- Trial name
- PSIC-TSA (NCT04663022)
- Testing
- Dunn's sensory profile questionnaire
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Toulouse
Temporomandibular Joint Disorders, Temporomandibular Disorder
TMJ Dysfunction: Effects on Proprioception, Pain, and Body Awareness
The term "temporomandibular joint dysfunction" (TMJ dysfunction) refers to a range of anatomical and functional problems, with or without clinical signs and symptoms, that affect the TMJ and/or the chewing muscles.
- Trial name
- NCT06558318
- Testing
- Assessment of temporomandibular dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Nagihan Acet
Pain, Pain Management
Pain in Aging Former Athletes, Master's Athletes, and Nonathletes
The goal of this clinical trial is to determine how male and female former athletes experience pain and respond to moderate-intensity exercise (strength versus aerobic) compared with both current master's athletes and…
- Conditions
- Pain, Pain Management, Athlete, Exercise Training
- Trial name
- PAIN (NCT07502742)
- Testing
- Moderate-Intensity Strength Exercise Intervention, Moderate-Intensity Aerobic Exercise Intervention
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marquette University
Pacifier, Infant Development
Pacifier Use and Infant Development
Pacifier use reduces the risk of sudden infant death syndrome, and nonnutritive sucking has been shown to improve physiological balance and feeding in premature infants.
- Conditions
- Pacifier, Infant Development, Sensory Processing Disorder
- Trial name
- NCT06889441
- Testing
- Test of sensory function in infants, The Peabody Developmental Motor Scales-Second Edition, Infant/toddler sensory profile
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Sensory Modulation Disorder, Sensory Over-Responsivity
Examining the Efficiency of Neurofeedback Therapy on Adults With Sensory Over Responsivity
Sensory Over-Responsivity (SOR) is characterized by a disruption in regulating sensory stimuli and can significantly impact pain perception and restrict daily participation and quality of life.
- Trial name
- NCT03837795
- Testing
- Neurofeedback treatment
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Hearing Loss, Low Vision
Self-management for Dual Sensory Impaired
This study aims to determine the effectiveness of a self-management program for elderly with an acquired and concurrent hearing and visual impairment due to age-related disease processes.
- Trial name
- NCT01217502
- Testing
- Self management program
- Where
- 4 sites in Netherlands
- Volunteers
- 89 people
- Sponsor
- Radboud University Medical Center