Clinical trials: Sensory Function
Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Smell Loss
Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
The goal of this observational study is to learn what can predict the return of the sense of smell in patients with chronic rhinosinusitis with nasal polyps being treated with dupilumab.
- Trial name
- NCT06892704
- Testing
- Dupilumab - Standard Dose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Hearing Loss, Bilateral Sensorineural, Progressive
Quality Control of CE-Certified Phonak Hearing Aids - 2017_13
A methodical evaluation of new CE-labelled Phonak Hearing Systems is intended to be conducted on hard of participants with a hearing loss to grant quality control prior to product launch.
- Trial name
- NCT03131557
- Testing
- Line extension of the Phonak Audéo B product family, Phonak Audéo B
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Hearing Loss
The Hearing Aid Effectiveness After Aural Rehabilitation (HEAR) Trial
This study compares the effectiveness of hearing aid appointments provided in a group format to those provided in an individual format.
- Trial name
- NCT00260663
- Testing
- Group hearing aid fittings, Group hearing aid follow-up
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- US Department of Veterans Affairs
Arthroplasty, Replacement, Hip
Ketamine Associated With Morphine PCA After Total Hip Arthroplasty
Ketamine (an analgesic drug often associated with morphine in the treatment of Opioid Induced Hyperalgesia) is often mixed in Morphine PCA syringe.
- Trial name
- KETAMINE (NCT00797264)
- Testing
- Ketamine-Morphine, Morphine, Postoperative PCA of Ketamine and morphine
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Retinal Disease, Macular Degeneration
Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.
The goal of this clinical study is to evaluate the safety and efficacy of novel stem cell formulation in patients having Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (d-AMD).
- Conditions
- Retinal Disease, Macular Degeneration, Age-Related Macular Degeneration, Geographic Atrophy
- Trial name
- NCT06394232
- Testing
- Eyecyte-RPE™
- Where
- 3 sites in India
- Volunteers
- 54 people
- Sponsor
- Eyestem Research Pvt. Ltd.
Healthy
The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players
The aim of this study isto investigate the influence of acute static stretching on the ankle joint position sense of soccer players.
- Trial name
- NCT06320977
- Testing
- Static Stretching
- Where
- Portugal
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Fernando Pessoa
Olfactory Dysfunction, Smell Loss
Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults
The goal of this clinical trial is to learn if ScentCare, a novel olfactory training device and accompanying companion web-based application, will lead to improved olfactory and well-being outcomes in elderly patients with…
- Conditions
- Olfactory Dysfunction, Smell Loss, Anosmia, Hyposmia
- Trial name
- SPLENDOR-OA (NCT06733636)
- Testing
- Sudoku Puzzles, ScentCare (Olfactory Training Device)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Amblyopia, Motion Sickness
Impact of Different Types of Virtual Reality Games on Motion Sickness and Ocular in Adults: A Pilot Study
The research project titled "The Impact of Immersive Virtual Reality Training on Adult: Motion Sickness, and Ocular Surface: A Pilot Study" aimed to evaluate the initial safety impact of head-mounted virtual reality (HMVR)…
- Conditions
- Amblyopia, Motion Sickness, Dry Eye
- Trial name
- NCT06354309
- Testing
- Virtual reality game
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
COVID-19 Respiratory Infection
Oral Symptoms of COVID-19 Among Infected Medical Doctors
Oral symptoms of corona virus disease have been reported by many studies. The lack of direct contact between the dentist and the patient during the active disease presented an obstacle to build a strong body of evidence.
- Trial name
- NCT05697081
- Testing
- Medical doctors infected with COVID-19
- Where
- Egypt
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Diabetes Mellitus
Effect of 10mg Domperidone on Gastric Emptying of a High-fat Meal and Appetite Sensations in Healthy Adults
The purpose of this study is to determine whether domperidone was sufficient to accelerate gastric emptying of a high-fat solid meal and reduce satiety responses in a healthy adult population.
- Trial name
- NCT01347814
- Testing
- Domperidone 10mg
- Where
- Ireland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Sensorineural Hearing Loss, Cytomegalovirus Infection
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts
This study will try to identify and understand the genetic factors that lead to an inner ear malformation called "enlarged vestibular aqueducts", that can be associated with hearing loss.
- Trial name
- NCT00023036
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Otosclerosis of Middle Ear, Unilateral Hearing Loss
Study of Binaural Squelch Effect in Unilateral Otosclerosis
Patients with unilateral transmission hypoacusis due to otosclerosis undergoing stapedectomy surgery will be prospectively included.
- Trial name
- CBOU (NCT03587792)
- Testing
- stapedectomy
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Grenoble
Balance Impairments in Stroke Patients
Can Lumbar Mulligan Mobilization Improve Gait, Balance, and Trunk Position Sense After Stroke?
Stroke is a pathology caused by disturbances in the brain's arterial circulation, leading to high morbidity rates. Individuals who experience a stroke often face neurological impairments such as motor, sensory, and cognitive…
- Trial name
- NCT06887114
- Testing
- Experimental Group (Mulligan Mobilization + Conventional Therapy), (Conventional Therapy Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulhane School of Medicine
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Noise-induced Hearing Loss
Test of Hearing Health Education Programs for Farm and Rural Youth
Farm and rural youth have frequent exposure to hazardous noise on the farm and recreationally, and have an increased prevalence of noise-induced hearing loss (NIHL).
- Trial name
- FARMYOUTHEAR (NCT02472821)
- Testing
- Interactive youth educational program, Internet-based educational booster
- Where
- United States
- Volunteers
- 2,093 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Conduction, Hearing Loss, Conductive
Post-market Evaluation of the Transition From the Baha Connect System to the Osia System in Adult Bone Conduction Implant Recipients
The goal of this interventional study is to confirm the safety and performance of the latest generation Osia System and to examine its benefits compared to the Baha Connect System in adults with mixed or conductive hearing loss…
- Conditions
- Bone Conduction, Hearing Loss, Conductive, Hearing Loss, Mixed
- Trial name
- OSIRIS (NCT07130136)
- Testing
- Cochlear™ Osia® System, Cochlear™ Baha® System
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Cochlear
Multiple Sclerosis
Isokinetic Exercises in Patients With Multiple Sclerosis
The investigators evaluated the effects of isokinetic muscle strengthening exercises of the quadriceps and hamstring on muscle strength, joint position sense, pain, kinesiophobia and quality of life in patients with multiple…
- Trial name
- NCT03779724
- Testing
- exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aksaray University Training and Research Hospital
Pain, Hyperalgesia
Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia
The aim of this study was to determine if the addition of ketamine reduces remifentanil-induced hyperalgesia, improves its analgesic effect, inhibits IL(interleukin)-6 and IL-8 (inflammatory cytokines), and stimulates IL-10 (an…
- Conditions
- Pain, Hyperalgesia, Inflammatory Response
- Trial name
- NCT01301079
- Testing
- Ketamine, Saline
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Visual Fields Hemianopsia, Stroke, Ischemic
Repetitive Transcranial Magnetic Stimulation for Post-Stroke Visual Field Defects
Visual field defects (VFD) usually do not show improvement beyond 12 weeks from onset. Plasticity occurs in areas of residual vision (ARV) at the visual field which are the functional counterpart of partially damaged brain…
- Conditions
- Visual Fields Hemianopsia, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT04021160
- Testing
- High frequency repetitive transcranial magnetic stimulation (rTMS)
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ain Shams University
Tinnitus
Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.
Tinnitus is a widespread problem that affects the quality of life of millions globally. Few treatments have been found to be effective for subjective tinnitus and to have a significant improvement on quality of life.
- Trial name
- TINNITY (NCT05300594)
- Testing
- Plant extracts, vitamins and mineral
- Where
- France
- Volunteers
- 110 people
- Sponsor
- CEN Biotech
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