Clinical trials: Sensory Function
Hearing Loss, Age-Related, Hearing Aids
Communication Training in Hearing Aid Users
The objective of the current research project is to investigate the effectiveness of communication training in first-time hearing aid users with mild to moderate hearing loss delivered in-person in groups or individually.
- Conditions
- Hearing Loss, Age-Related, Hearing Aids, Sensorineural Hearing Loss, Speech Intelligibility
- Trial name
- NCT07798453
- Testing
- Cognitive screening, Audiological Assessment, Questionnaires
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University Ghent
Hemianopia, Hemianopsia
Rehabilitating Visual Deficits Caused by Stroke
This research aims to understand the efficacy of a visual training task to improve visual loss after stroke, also known as hemianopia.
- Conditions
- Hemianopia, Hemianopsia, Quadrantanopia, Stroke Induced Vision Loss
- Trial name
- NCT04878861
- Testing
- Training in the blind field
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Tinnitus
Management of Acute Tinnitus With Migraine Medications
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life.
- Trial name
- NCT06799169
- Testing
- Nortriptyline, Topiramate, Paroxetine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Irvine
Aging, Hearing Loss
Working Memory Changes With Aging and Hearing Loss
Hearing loss is one of the most common health concerns affecting 1 in 3 Americans over 60 years of age rising to 1 in 2 for those over 85 years old.
- Trial name
- NCT01253031
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Tinnitus, Neural Therapy of Huneke
The Effects of Conventional Therapy on Tinnitus, Disability, and Quality of Life in Patients With Tinnitus
A randomized, single-blind, controlled trial to evaluate the effects of neural therapy on tinnitus severity, disability, and quality of life in patients with tinnitus.
- Trial name
- NCT07334002
- Testing
- Neural Therapy of Huneke, Betahistine 24 mg bid (Betaserc)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Healthy
The Effect of Different Doses (Mass) of Local Anesthetic on Duration of Adductor Canal Block in Healthy Volunteers - Part 2
To investigate whether increased dose of local anesthetic (lidocaine) increases duration of peripheral nerve block (adductor canal block) and to develop a model for assessing duration of peripheral nerve blockades.
- Trial name
- NCT02172729
- Testing
- Adductor canal block with 20 ml lidocaine, single bolus
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autism Spectrum Disorder
Effects of Kinetic Sand on Functional Reach and Eye-Hand Coordination in Children With Autism
A quasi-experimental pre-post study will be conducted at pediatric therapy clinics and special education centers, involving 17 children aged 6-12 years diagnosed with mild to moderate ASD, selected through convenient sampling.
- Trial name
- NCT07578987
- Testing
- Kinetic Sand Play
- Where
- Pakistan
- Volunteers
- 17 people
- Sponsor
- Riphah International University
Macular Polypoidal Choroidal Vasculopathy (PCV)
Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy
This study is a 60-week, two-arm, randomized, open-label, active-controlled, multi-center study in patients with Polypoidal choroidal vasculopathy (PCV) who have not previously received anti-Vascular endothelial growth factor…
- Trial name
- PROUD (NCT05666804)
- Testing
- Brolucizumab 6mg
- Where
- 15 sites in South Korea
- Volunteers
- 148 people
- Sponsor
- Novartis Pharmaceuticals
Hearing Loss, Cancer
Study to Evaluate the Safety and Pharmacokinetics of SPI-1005
A study to determine the safety, tolerability, and pharmacokinetics of SPI-1005 capsules in healthy adults.
- Trial name
- NCT01452607
- Testing
- SPI-1005
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sound Pharmaceuticals, Incorporated
Diabetic Retinopathy
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)
This study will demonstrate that tarcocimab 5 mg is superior to sham treatment in participants with DR.
- Trial name
- GLOW2 (NCT06270836)
- Testing
- Tarcocimab
- Where
- 39 sites in United States, Puerto Rico
- Volunteers
- 255 people
- Sponsor
- Kodiak Sciences Inc
Chronic Heart Failure
A CSM-Based Volume Management Program for Chronic Heart Failure
Study Title:A Nurse-Led Intervention Program Based on the Common-Sense Model of Self-Regulation for Volume Management in Patients with Chronic Heart Failure: A Randomized Controlled Trial Brief Summary: The goal of this clinical…
- Trial name
- NCT07686536
- Testing
- CSM-Based Intervention Group, Standard Care (in control arm)
- Volunteers
- 88 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Carpal Tunnel Syndrome, Entrapment Neuropathies
Nerve Entrapment in Diabetic Patients
The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare…
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathies, Nerve Compression Syndromes, Diabetes Complications
- Trial name
- NCT00775333
- Testing
- Outcome after carpal tunnel release
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Skane University Hospital
Ischemic Stroke, Acute, Stroke
NeuroGlove fMRI Study
This is a prospective, single center, interventional clinical study containing two cohorts the treatment cohort and control cohort. A total of 13 subjects will be enrolled.
- Trial name
- NCT05961293
- Testing
- NeuroGlove
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
CABP2-related Auditory Synaptopathy, Hearing Impairment
CABP2 Patient Registry and Natural History Study
This registry is designed to collect comprehensive information about the molecular genetic diagnoses and clinical information of individuals with CABP2-associated hearing impairment to support a natural history study.
- Trial name
- NCT06680934
- Testing
- Molecular genetic testing and audiometry
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Medical Center Goettingen
Anterior Cruciate Ligament Injury
Effects of Low-intensity Strength Training With Concomitant Blood Flow Restriction on Pain Perception in Patients With Anterior Cruciate Ligament Surgery
After surgical treatment of a tear of the anterior cruciate ligament, physiotherapeutic exercises are done as standard therapy. This is to achieve a rapid improvement in pain and knee function.
- Trial name
- BFR (NCT06699264)
- Testing
- Blood Flow Restriction Training, Training without BFR
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Praxisklinik Rennbahn AG
Tinnitus, Subjective, Tinnitus, Bilateral
Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus
The main objective of our study is to evaluate the effect of combinated antioxidants therapy with Adepsique® (amitriptyline, perphenazine, and diazepam) on patients with tinnitus chronic symptoms, evaluating the levels of…
- Conditions
- Tinnitus, Subjective, Tinnitus, Bilateral, Antioxidant Therapy, Psychiatric Drugs
- Trial name
- NCT05646693
- Testing
- Drusen Mega®, Sertraline
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- University of Guadalajara
Pulsatile Tinnitus
Dural Sinus Stenting of Low Grade Dural Arteriovenous Fistulae (DAVF) for Pulsatile Tinnitus Treatment
The goal of this randomized trial to assess the angiographic efficacy of venous stenting in dural arteriovenous fistulae (DAVF) via improvment on Cognard's Classification as compared to no intervention at 6 months Participants…
- Trial name
- INVENT (NCT05679271)
- Testing
- Venous stenting, Standard of care
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bordeaux
Visual Impairment
Quality of Life in Italian Visually Impaired Patients
Clinical register of visual rehabilitation activity and observational study on the validation of the VA LV VFQ questionnaire in the Italian context
- Trial name
- SOPIITA (NCT05752214)
- Testing
- WEB Register
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Amore Filippo
Visual Impairment, Healthy
Touching the World With a Cane: Cognitive and Neural Processes
The use of tools is ubiquitous in our lives and allows us to expand the sensorimotor capacities of our body. Much research has been done on the subject in sighted people over the past decades.
- Trial name
- TOOL_TOUCH (NCT05199896)
- Testing
- Behavioral protocol, EEG protocol, fMRI protocol
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Globus
The Effect of Laryngeal Manual Therapy as a Management of Globus
The purpose of this study is to assess the effect of laryngeal manual therapies in the treatment of globus (sensation of a lump in the throat).
- Trial name
- NCT04436146
- Testing
- laryngeal manual therapies
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- HaEmek Medical Center, Israel
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