Clinical trials: Sensory Function
Mixed Hearing Loss
Evaluation of Actual Maximum Gain in Bone Anchored Devices
This study will look at how much sound amplification (gain) different bone-anchored hearing devices can provide. The goal is to understand if there are differences between devices and whether these differences affect how well the…
- Trial name
- NCT07294976
- Testing
- Bone Anchored Device A, Bone Anchored Device B, Bone Anchored Device C
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Oticon Medical
Cancer Pains
Change the Dose Frequency of Controlled-Release Oxycodone to Refractory Pain
Many patients with cancer experience moderate to severe pain that requires treatment with strong opioids, of which oxycodone and morphine are examples, they are widely applied in clinical treatment because of sustained-released…
- Trial name
- NCT03639415
- Testing
- Increasing the Controlled-Release Oxycodone dose frequency
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Cancer
Psychoeducation for Anxiety, Depression, Cognitive Avoidance, and Sense of Coherence in Women With Cancer
This study evaluates the effectiveness of a structured psychoeducational intervention on anxiety, depression, cognitive avoidance, and sense of coherence in women with cancer.
- Trial name
- NCT07837440
- Testing
- Structured Psychoeducational Intervention
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Ardakan University
Type1 Diabetes Mellitus
Comparison of Motor and Sensory Functions of the Hand in Children With Type 1 Diabetes Mellitus and Their Healthy Peers
Type 1 Diabetes Mellitus (T1DM) is a condition where the body cannot produce a hormone called insulin. Although it is commonly seen in children and young people, it can occur at any age.
- Trial name
- NCT06206317
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Erdal AYDIN
Hearing Loss, Cochlear Implants
Encoding Temporal Fine Structure for Cochlear Implants
The goal of this study is to improve music and speech perception for cochlear implant users. Presently, most cochlear implants discard the temporal fine structure of sound, which is information that is widely believed to…
- Trial name
- TFS4CIs (NCT04708717)
- Testing
- Stimulation Rate, Electrode Location
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hearing Loss, Bilateral Sensorineural, Progressive
Quality Control of CE-Certified Phonak Hearing Aids - 2016_37
A methodical evaluation of new CE-labelled Phonak Hearing Systems is intended to be conducted on hard of participants with a hearing loss to grant quality control prior to product launch.
- Trial name
- NCT03108768
- Testing
- Hearing Aid (Successor of Phonak Virto V), Hearing Aid (Phonak Virto V)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Meniere's Disease
SPI-1005 for the Treatment of Patients With Meniere's Disease
This study will evaluate the safety, efficacy, and Pharmacokinetics (PK) of two dose levels of SPI-1005 administered for 28 days compared to placebo in patients with Meniere's disease.
- Trial name
- NCT03325790
- Testing
- 200mg SPI-1005 BID, 400mg SPI-1005 BID
- Where
- 13 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Hearing Loss, Sensorineural
Investigating Electrical Categorical Loudness Scaling Using a Mobile Research App in Experienced Adult Cochlear Implant Participants
This clinical study will evaluate a feature of the investigational Nexus Research System used for programming cochlear implants.
- Trial name
- ELSA (NCT07077070)
- Testing
- Standard Electrical Categorical Loudness Scaling task (Standard-ELS), Fast Electrical Categorical Loudness Scaling task (Fast-ELS)
- Where
- 3 sites in United States, Belgium
- Volunteers
- 20 people
- Sponsor
- Cochlear
Sudden Hearing Loss, Obstructive Sleep Apnea
The Effect of PAP on ISSHL Comorbided With OSA
This clinical randomized controlled study is to explore the effect of positive airway pressure(PAP) on patients in Beijing Tsinghua Changgung Hospital diagnosed with both idiopathic sudden sensorineural hearing loss…
- Trial name
- NCT04192656
- Testing
- non-invasive positive airway pressure, Methylprednisolone Hemisuccinate, Ginaton
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hyperalgesia, Neurodynia
GW406381 In Patients With Peripheral Nerve Injury
The findings from preclinical animal models confirm the peripheral anti-inflammatory/analgesic activity of GW406381 and also suggest contribution of a central site of action to the anti-hyperalgesic efficacy that may not be…
- Conditions
- Hyperalgesia, Neurodynia, Pain, Trauma
- Trial name
- NCT00279032
- Testing
- GW406381
- Where
- 5 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Primary Dysmenorrhea
"Knee Joint Position Sense and Dynamic Balance in Females With Primary Dysmenorrhea
The purpose of the study is to assess knee joint position sense, pain and dynamic balance in female with primary dysmenorrhea.
- Trial name
- NCT07239232
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ovarian Cancer (OvCa), Fallopian Tube Cancers
Taste Alteration, Sarcopenia, and Malnutrition in Gynecologic Cancer Patients Receiving Carboplatin-Paclitaxel Chemotherapy
This observational study aims to evaluate chemotherapy-induced taste alterations, sarcopenia, and malnutrition in patients with gynecologic malignancies (ovarian, fallopian tube, and endometrial cancer) treated with standard…
- Conditions
- Ovarian Cancer (OvCa), Fallopian Tube Cancers, Endometrial Cancer, Chemotherapy-Induced Taste Alteration
- Trial name
- GYM-TASTE (NCT07154966)
- Testing
- Standard Chemotherapy (Carboplatin-Paclitaxel)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ankara Etlik City Hospital
Craniosynostosis, Muenke Syndrome
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)
This study will explore the range and type of medical and developmental problems in patients with Muenke syndrome, a condition that results when one or more of the suture between the bones of the skull close before birth.
- Trial name
- NCT00106977
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Gestational Diabetes, Hearing Loss
Hearing Screening Outcomes of Two Screening Tests in Newborns of Gestational Diabetic Mothers
In this study, the investigators have aimed to investigate whether GDM is a risk factor for hearing impairment in newborns. To the investigators knowledge, this study is the first prospective, controlled study on this subject.
- Trial name
- NCT04845412
- Testing
- Hearing screening tests
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Central Retinal Vein Occlusion
Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Central Retinal Vein Occlusion (CRVO)
Provide efficacy and safety data on intravitreal injections of ranibizumab 0.5 mg in patients with visual impairment due to macular edema secondary to CRVO
- Trial name
- Camellia (NCT01976312)
- Testing
- Ranibizumab 0.5 mg
- Where
- 34 sites in China, Hong Kong and 5 more
- Volunteers
- 252 people
- Sponsor
- Novartis Pharmaceuticals
Sensation Disorders
The Effects of Chiropractic Care in Children With Parent-reported Sensory Processing Disorder
This trial's main aims are to investigate the feasibility of implementing our novel assessment battery in tandem with normal and customary chiropractic care in a practice-based setting using a pediatric population with…
- Trial name
- NCT06413719
- Sponsor
- Life University
Hearing Loss
Hearing Aid Algorithms for Sudden Sounds
This study explores the impact of hearing aid settings for managing sudden sounds on speech comprehension and recall in individuals with hearing loss.
- Trial name
- NCT06340919
- Testing
- Sudden Sound Reduction Setting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Overactive Bladder Syndrome, Bladder Outlet Obstruction
Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity
Urodynamic examination evaluates storage and empting phases of the urinary bladder. It enables the clinician to correlate physiologic findings to patients' complains.
- Conditions
- Overactive Bladder Syndrome, Bladder Outlet Obstruction, Benign Prostate Enlargement, Stress Incontinence (Female) (Male)
- Trial name
- NCT03486639
- Testing
- IPSS questionnaire
- Where
- Israel
- Volunteers
- 330 people
- Sponsor
- Assaf-Harofeh Medical Center
Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene
A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations
This is an observational study to examine the characteristics of gene-related hearing loss in pediatric participants with biallelic otoferlin (OTOF) Mutations, Gap Junction Beta 2 (GJB2) Mutations, or Digenic GJB2/Gap Junction…
- Conditions
- Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene, Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes
- Trial name
- ENSEMBLE (NCT06019481)
- Where
- 2 sites in United States
- Sponsor
- Regeneron Pharmaceuticals
Peripheral Nerve Injury, Nerve Injury
Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration
PEG is a fusogen, a type of chemical that aids in mediating cell fusion. PEG helps nerve cells recover neuronal continuity by removing plasmalemmal-bound water which opens the axonal ends on both sides of the injury.
- Trial name
- NCT04270019
- Testing
- Polyethylene Glycol 3350, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
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