Clinical trials: Sensory Function
Tinnitus, Pulsatile Tinnitus
Venous Sinus Stenting To Treat Intractable Pulsatile Tinnitus Caused By Venous Sinus Stenosis
There have been few published studies that examine the efficacy and safety of endovascular treatments on patients with pulsatile tinnitus with venous stenosis.
- Conditions
- Tinnitus, Pulsatile Tinnitus, Venous Sinus Stenosis, Dural Sinus Stenosis
- Trial name
- NCT02734576
- Testing
- Venous Sinus Stenting with the Precise Pro Stent
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University
Thermal Hyperalgesia, Anxiety
A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients
Burn-related pain is severe and often difficult to manage. Healthcare workers struggle with keeping burn patients comfortable, especially when these patients undergo dressing changes of their burn wounds of their skin since these…
- Conditions
- Thermal Hyperalgesia, Anxiety, Pain
- Trial name
- NCT02336308
- Testing
- Ketamine
- Where
- United States
- Sponsor
- University of Colorado, Denver
Wolfram Syndrome
Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1
Wolfram syndrome (WFS:OMIM 222300) is a group of inherited disorders that usually appear in childhood and cause diabetes, optic atrophy leading to loss of vision, deafness and often diabetes insipidus.
- Trial name
- NCT05659368
- Testing
- Tirzepatide
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Ospedale San Raffaele
Hearing Loss, Sensorineural, Hearing Loss
Clinical Utility of Residual Hearing in the Cochlear Implant Ear
The current study is a randomized multi-center clinical trial that investigates the role an intraoperative hearing monitoring system (electrocochleography) has on helping to save residual hearing in patients undergoing cochlear…
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Hearing Loss, Bilateral
- Trial name
- NCT04707885
- Testing
- Electrocochleography
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Ohio State University
Olfactory Disorder, Anosmia
Smell Changes & Efficacy of Nasal Theophylline
This study evaluates the efficacy and safety of nasal theophylline irrigation in treating smell loss related to a viral respiratory infection.
- Conditions
- Olfactory Disorder, Anosmia, Viral Infection, Theophylline Causing Adverse Effects in Therapeutic Use
- Trial name
- SCENT (NCT03990766)
- Testing
- Theophylline, Saline Nasal
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Hearing Impairment
Clinical Evaluation of the Nuance Audio Hearing Aid in Adults With Mild to Moderate Hearing Difficulties
The research will produce clinical effectiveness performance metrics using standardised procedures of the Nuance Audio hearing device.
- Trial name
- NCT07100522
- Testing
- Hearing aid in spectacle frame form factor, hearing aid
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Luxottica Group S.p.A.
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Retinitis Pigmentosa
Prospective Natural History Study of Retinitis Pigmentosa
This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6a or PDE6b gene mutations.
- Trial name
- PHENOROD2 (NCT04285398)
- Testing
- Ophthalmic examinations, Mobility Test
- Where
- 2 sites in United States, France
- Volunteers
- 82 people
- Sponsor
- SparingVision
Rheumatoid Arthritis
Textured Insoles and Foot Massage in Individuals Diagnosed With Rheumatoid Arthritis
The aim of this study is to determine and compare the effects of using textured insoles and plantar massage on balance in patients with rheumatoid arthritis.
- Trial name
- NCT05045898
- Testing
- plantar massage, textured insoles
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tinnitus
Navigated Repetitive TMS for Chronic Tinnitus
This study is testing whether a special type of brain stimulation called neuronavigated TMS can help reduce tinnitus (ringing in the ears).
- Trial name
- NCT07435298
- Testing
- navigated rTMS
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Focus: Surgical Smoke During Laparoscopic Surgery
Assessment of a New Surgical Smoke Clearing Technology in Laparoscopic Cholecystectomy
The study will examine the safety and performance of a new surgical smoke clearance system designed for use during laparoscopic surgery.
- Trial name
- Innervision (NCT01534832)
- Testing
- Innervision Surgical Smoke Removal System
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Asalus Medical Instruments Limited
Benign Paroxysmal Positional Vertigo
Evidence Based Best Care Practice for Benign Paroxysmal Positional Vertigo
The study evaluates a theory-based educational intervention and implementation strategy on the use of the Dix-Hallpike test (DHT) and Canalith Repositioning Maneuver (CRM) in a community Emergency Department (ED) setting.
- Trial name
- NCT02809599
- Testing
- DIZZTINCT
- Volunteers
- 7,635 people
- Sponsor
- University of Michigan
Cataract
Comfort Operative Ocular Light Study
Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes.
- Trial name
- COOL (NCT05085314)
- Testing
- Ngenuity digital 3D microscope, Conventional microscope
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Tinnitus, Subjective
ICCAC-ToNF & Tinnitus
Prevalence of chronic subjective tinnitus is rising with age and associated with maladaptive oscillatory changes in auditory as well as non-auditory regions of the brain such as the insula and the anterior cingulate cortex which…
- Trial name
- ICCAC (NCT03895047)
- Testing
- tomographic EEG Neurofeedback Training
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Hearing Loss, Unilateral, Deafness, Unilateral
Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for…
- Trial name
- PAS-SSD (NCT05318417)
- Testing
- The Cochlear™ Nucleus® Cochlear Implant (CI) System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cochlear
Budesonide, Olfaction Disorders
Trial Evaluating the Efficacy of Local Budesonide Therapy in the Management of Hyposmia in COVID-19 Patients Without Signs of Severity
The initial symptoms described in the first cases of COVID-19 were mainly fever and respiratory signs. Recently, there has been an increase in cases of hyposmia without associated nasal obstruction or rhinorrhea.
- Conditions
- Budesonide, Olfaction Disorders, SARS-CoV-2, Anosmia
- Trial name
- COVIDORL (NCT04361474)
- Testing
- Budesonide Nasal, Physiological serum
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Conductive Hearing Loss, Unilateral Partial Deafness
Minimally Invasive Surgery for Ponto Bone Anchored Hearing Implants
The objective of this study is to make a comparison between two surgical techniques used when implanting a Ponto bone anchored hearing system.
- Conditions
- Conductive Hearing Loss, Unilateral Partial Deafness, Mixed Conductive-sensorineural Hearing Loss
- Trial name
- C50 (NCT02438618)
- Testing
- Surgery for Ponto bone anchored hearing aids
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Oticon Medical
Central Post-stroke Pain
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
The goal of this observational study is to examine the association between exact lesion location and presence of thalamic CPSP (Central post-stroke pain) in a larger number of patients after thalamic stroke.
- Trial name
- NCT05679297
- Testing
- Quantitative sensory testing (QST), Magnetic resonance imaging (MRI), Clinical interview/exam
- Where
- Switzerland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Blepharoptosis, Blepharochalasis, Superior
Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries
The aim of the study: Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface Surgeries. Study design: an interventional study that will be conducted at the ophthalmology department, Meir hospital…
- Conditions
- Blepharoptosis, Blepharochalasis, Superior, Ectropion, Entropion
- Trial name
- NCT02638610
- Testing
- Cochet-Bonnet aesthesiometer
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Visual Acuity, Refractive Errors
Pre-symptomatic Screening of Visual Acuity in Pre-school Students
The present research process is a prospective, non-interventional clinical study that will be conducted -under the auspices of the Democritus University of Thrace (DUTH)- in the pre-school students of the city of Alexandroupolis…
- Conditions
- Visual Acuity, Refractive Errors, Low Vision, Vision Disorders
- Trial name
- NCT05835193
- Testing
- Diagnostic Test: Distance Visual Acuity Examination
- Where
- Greece
- Volunteers
- 1,098 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
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