Clinical trials: Sensory Function
Digestion, Happiness
Parental Notions and Clinical Experiences About Child's Gut Comfort, Overall Satisfaction and Sense of Well-being When Consuming a New Toddler Milk
This is a prospective, open-label, single-arm study in a real-world setting of healthy Chinese toddlers provided with new toddler milk for a total of 4 weeks (28 days).
- Conditions
- Digestion, Happiness, Temperament
- Trial name
- NCT04768933
- Testing
- Toddler Milk
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Continuous Femoral Nerve Blocks in Healthy Volunteers
Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function
To determine if the way local anesthetic, or numbing medication, is delivered through a tiny tube next to the nerves that go to the thigh affects the strength and sensation in the thigh.
- Trial name
- NCT01263249
- Testing
- Catheter Anterior to the Femoral Nerve, Catheter Posterior to the Femoral Nerve
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Diabetes, Deafness
American Sign Language-Accessible Diabetes Education
ASL-ADE will evaluate the efficacy of an ASL-interpreted diabetes educational intervention to the end of improving the health literacy of the target population and addressing their disparate health outcomes.
- Trial name
- ASL-ADE (NCT03980808)
- Testing
- American Sign Language-Accessible Diabetes Education, Control Intervention
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2
Balance Control and Recovery in Diabetes Peripheral Neuropathy
In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults over 50 years.
- Conditions
- Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2, Diabetic Peripheral Neuropathy Type 2 - Uncontrolled, Healthy Aging
- Trial name
- DPN (NCT06544876)
- Testing
- sit-to-stand, stand to sit, standing perturbation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lisa Griffin
Homonymous Hemianopia
Homonymous Hemianopia in Childhood
The study will consist of two connected components at a single centre. Phase 1 is observational, phenotyping children with Homonymous hemianopia (HH).
- Trial name
- HHIC (NCT06115317)
- Testing
- Prism
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Institute of Child Health
Single Sided Deafness
Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness
The objective of this feasibility study is to obtain preliminary safety and efficacy data associated with cochlear implantation in individuals with severe to profound sensorineural hearing loss contralateral to an ear with…
- Trial name
- NCT01670006
- Testing
- Cochlear Nucleus Cochlear Implant System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cochlear
Tinnitus
A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients
The principal hypotheses to be tested is that Mindfulness Based Cognitive Therapy (MBCT) reduces the distressing impact of tinnitus to a significantly greater extent than a waiting list control or relaxation therapy.
- Trial name
- NCT02059447
- Testing
- No treatment waiting period, Mindfulness Based Cognitive Therapy, Relaxation Therapy
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University College London Hospitals
Common Cold
Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough
This is a 1-treatment arm, open label design. This 1-day study includes a screening on day of attendance at clinic, followed by a washout period of 30 minutes to 8 hours (if participants are eligible for dosing the same day).
- Trial name
- NCT02822287
- Testing
- Acetylcystine
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- GlaxoSmithKline
Pain, Neuropathic
Gabapentin and Donepezil Combination on Experimental Human Pain Models
This study will compare the effects of gabapentin alone, and gabapentin + donepezil given together in two types of experimental electrical pain tests in up to 48 healthy male subjects (after 24 recruited in the first cohort an…
- Trial name
- NCT01485185
- Testing
- Gabapentin lower dose, Donepezil, Gabapentin higher dose
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hearing Loss
Evaluation of Novel Noise Reduction Principles in Hearing Instruments
In the study, the speech intelligibility in noise (Outcome) between a novel noise reduction algorithm (Intervention) versus the standard noise reduction (Comparator) will be tested in adults with a N3-N4 hearing loss (Population)…
- Trial name
- NCT05582408
- Testing
- Measures of Standard Noise Reduction NR1, Measures of Noise Reduction Principle NR2, Measure of Noise Reduction Principle NR3
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Sonova AG
Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness
Influence of Physical Therapy for Foot and Ankle in the Gait of Individuals With Diabetic Neuropathy
The hypothesis is that a physical therapy intervention for foot and ankle of diabetic neuropathic individuals would affect positively the way they walk, lowering the harmful forces that these segments receive, that are associated…
- Conditions
- Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness, Foot and Ankle Range of Movement Restriction
- Trial name
- NCT01207284
- Testing
- Physical Therapy
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo General Hospital
Intracranial Hemorrhages, Traumatic Brain Injury
Evaluate the SENSE Device's Ability to Monitor and Detect Intracranial Hemorrhage
This study is a two-stage, pivotal, prospective, non-randomized, multi-center, within patient comparison of the SENSE device and the standard diagnostic test, head CT scan in patients with a diagnosis of primary spontaneous ICH…
- Trial name
- NCT04642443
- Testing
- SENSE Device
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Sense Diagnostics, LLC
Pain
Mechanisms of Pain Hypersensitivity in a Human Skin Inflammation Model
The main goal of this double-blind, randomized, placebo-controlled crossover study is to understand the molecular mechanisms of inflammation-induced increased pain sensitivity (hyperalgesia).
- Trial name
- NCT07092215
- Testing
- Synthetic interstitial fluid (SIF) / SIF neutral pH, Synthetic interstitial fluid (SIF) / SIF acidic pH, Synthetic interstitial fluid (SIF) / SIF acidic pH + BCTC 1 µM
- Where
- Austria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Stefan Heber
Diabetic Macular Edema
Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.
The purpose of this study is to generate additional safety and effectiveness data in Indian Diabetic macular edema (DME) patients that more closely resemble the real-world population intended to be treated with Brolucizumab.
- Trial name
- NCT05959304
- Testing
- brolucizumab
- Where
- 8 sites in India
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Hallux Valgus, Pain
Effects of Plantar Sensory Training in Individuals With Hallux Valgus.
Hallux valgus is a forefoot deformity with a high prevalence, which can progress to lateral deviation of the big toe, medial deviation of the first metatarsal, and subluxation of the first metatarsophalangeal joint in the future.
- Conditions
- Hallux Valgus, Pain, Balance; Distorted
- Trial name
- NCT05344755
- Testing
- Plantar Sensorial Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Tinnitus
Clinical Utility of Neuromodulation on Tinnitus
The aim of the present narrative review is to one of the first to critically evaluate the clinical effectiveness of neuromodulation as a therapeutic option for patients with tinnitus.
- Trial name
- NCT05674435
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- Hearing and Language Healthcare Center, China Medical University Hsinchu Hospital, Taiwan
Hearing Loss, Hearing Loss, Sensorineural
Evaluation of Artificial Intelligence-Integrated Hearing Aids for Individuals with Hearing Loss
The goal of this clinical trial will be to evaluate the efficacy of artificial intelligence-integrated hearing aids in individuals with hearing loss. The main questions to answer are: 1.
- Trial name
- NCT06792110
- Testing
- Artificial Intelligence Integrated Hearing Aid Use, Phonak Infineo Hearing Aid, Oticon Real Hearing Aid
- Volunteers
- 100 people
- Sponsor
- University of Washington
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Cochlear Hearing Loss
Listening Effort in Cochlear Implant Users
Listening with a cochlear implant remains difficult and most listeners will report high levels of listening effort.The present study is a "pilot" aiming to evaluate listening effort for cochlear implant users.
- Trial name
- NCT03212924
- Testing
- Pupillometry, Evaluation of speech comprehension in quiet, Evaluation of speech comprehension in noise
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Oticon Medical
Dizziness
Vestibular Rehabilitation and Otolith Dysfunction
Recent studies suggest that otolith dysfunction is a common finding in individuals with a history of head trauma/blast exposure and/or noise-induced hearing loss.
- Trial name
- NCT02652442
- Testing
- Centrifugation Distance, Centrifugation Duration, Centrifugation Schedule
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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