Clinical trials: Sentinel Lymph Node Detection
Lung Cancer
SLN Detection With Tc-MSA-ICG in Lung Cancer Patients
It is necessary to develop a technique of sentinel lymph node detection using radioactive fluorescent dual contrast agent consisting targetable albumin for specific marker to accurately determine whether or not the sentinel lymph…
- Trial name
- NCT05039905
- Testing
- 99mTc-MSA-ICG
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Korea University Guro Hospital
Ovarian Neoplasms, Sentinel Node
Sentinel Node Detection in Ovarian Cancer
Recently the investigators have shown that the SN procedure performed through the injection of tracers into the ovarian ligaments is feasible and promising in patients with clinical early stage ovarian cancer (OC).
- Trial name
- SONAR-2 (NCT02540551)
- Testing
- Injection of radioactive tracer combined with Patent Blue
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Maastricht University Medical Center
Sentinel Lymph Node, Endometrial Cancer
Sentinel Node Detection in Endometrial Cancer: A Consolidation Study on Detection Rates of Metastatic Disease
Evaluation of removal of Sentinel lymph nodes only for detection of pelvic lymph node metastases in high risk and low risk endometrial cancer.
- Conditions
- Sentinel Lymph Node, Endometrial Cancer, Lymphedema
- Trial name
- NCT03838055
- Testing
- Injection of tracer ( ICG) and detection of sentinel lymph nodes
- Where
- Sweden
- Volunteers
- 362 people
- Sponsor
- Region Skane
Head and Neck Cancer
Multicenter Phase II Study of Sentinel Node Detection in Squamous Cell Carcinoma T1-T2N0 of the Oropharynx Treated With Radiotherapy and Larynx Treated by Surgery, Laser or Robot
Fifty patients with squamous cell carcinoma of the larynx T1 or T2N0 will therefore have a 99mTc lymphoscintigraphy per operative.
- Trial name
- GS-OROPHARYNX (NCT03010553)
- Testing
- Detection and resection of sentinel lymph node
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Breast Cancer, Breast Neoplasms
Device Validation of Augmented-Reality ICG Fluorescence Imaging for Sentinel Lymph Node Detection in Breast Cancer
This study evaluates how accurately augmented-reality goggles with indocyanine green (ICG) near-infrared fluorescence can identify sentinel (first-draining) lymph nodes during breast cancer surgery.
- Conditions
- Breast Cancer, Breast Neoplasms, Sentinel Lymph Node, Lymphatic Metastasis
- Trial name
- NCT07683572
- Testing
- AR-ICG near-infrared fluorescence imaging
- Where
- North Macedonia
- Volunteers
- 200 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Melanoma, Stage I, Melanoma, Stage II
Sentinel Lymph Node Detection in Patients With Stage Ib-III Melanoma Using MSOT and ICG
In this study the investigators try to identify the sentinel lymph node in patients with stage Ib-III melanoma in a non-invasive manner without the use of a radioactive tracer by using the new MSOT technology.
- Conditions
- Melanoma, Stage I, Melanoma, Stage II, Melanoma Stage III
- Trial name
- MelanooMSOT (NCT05467137)
- Testing
- MSOT
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Recurent Vulvar Carcinoma
International Prospective Multicentre Study That Evaluate the Sentinel Lymph Node Detection Rate in Patients With First Local Recurrent Scamous Cell Carcinoma of the Vulva.
Acronym: VULCA-NODE Study Title: Sentinel Node Biopsy in Relapsed Vulvar Cancer Primary Objetive: To evaluate the SLN detection rate in the first recurrent vulvar carcinoma setting.
- Trial name
- VULCA-NODE (NCT07023601)
- Testing
- Sentinel Lymph Node Biopsy in first local recurrent vulvar carcinoma
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Sentinel Lymph Node, Head and Neck Squamous Cell Carcinoma
Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC
Head and neck squamous cell carcinoma is the sixth most common malignant tumor in the world. Cervical lymph node metastasis is frequently encounted on the date of diagnosis.
- Trial name
- NCT05437380
- Testing
- peritumoral microbubbles and contrast-enhanced ultrasonography
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Ovarian Cancer, Lymph Node Metastasis
Magtrial: Magtrace® as Tracer for Sentinel Lymph Node Detection in Early Stage Epithelial Ovarian Cancer
Epithelial ovarian cancer (EOC) remains the tumour with the most unfavourable prognosis within the field of gynaecological oncology.
- Trial name
- NCT05375526
- Testing
- Magtrace
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
Breast Cancer, Sentinel Lymph Node
Use of Superparamagnetic Iron Oxide (SPIO) in Sentinel Lymph Node Detection for Breast Cancer
Sentinel lymph node biopsy is mandatory during breast cancer operation for disease staging and treatment. The localization of sentinel lymph node is by the injection of radioisotope and blue dye, which is the gold standard.
- Trial name
- NCT05288686
- Testing
- sentinel lymph node biopsy procedure
- Where
- Hong Kong
- Volunteers
- 282 people
- Sponsor
- The University of Hong Kong