Clinical trials: Septic Shock, diet or lifestyle or exercise or nutrition or physical activity or counseling, open to volunteers
- Condition Septic Shock
- Drug or intervention diet OR lifestyle OR exercise OR nutrition OR physical activity OR counseling
- Status Open to volunteers
Septic Shock
POCUS-Guided Esmolol in Septic Shock: A Pilot RCT
The goal of this pilot clinical trial is to determine if conducting a larger study using point-of-care ultrasound (POCUS) to guide beta-blocker therapy in patients with septic shock is feasible.
- Trial name
- Epic-Beta (NCT07313605)
- Testing
- Esmolol
- Volunteers
- 100 people
- Sponsor
- John Basmaji
Septic Shock
Protocolized Reduction of Non-resuscitation Fluids Versus Usual Care in Septic Shock Patients
The objective of this trial is to assess the beneficial and harmful effects of a restrictive strategy for administration of non-resuscitation fluids in adult patients with septic shock.
- Trial name
- REDUSE (NCT06140147)
- Testing
- Protocolised reduction of non-resuscitation fluids, Usual care
- Where
- 22 sites in Finland, Sweden and 1 more
- Volunteers
- 1,850 people
- Sponsor
- Region Skane
Sepsis, Severe Sepsis With Septic Shock
Wearable Sweat Sensor for High-Concentration Lactate Monitoring in Critically Ill Patients
Blood lactate level is closely associated with the prognosis of patients with sepsis and septic shock. Clinical guidelines explicitly recommend blood lactate monitoring in septic patients and lactate-guided fluid resuscitation…
- Conditions
- Sepsis, Severe Sepsis With Septic Shock, Severe Sepsis Without Septic Shock
- Trial name
- NCT07716371
- Testing
- High-Concentration Sweat Lactate Wearable Monitoring Device, Commercial Sweat Collection Device (HELA)
- Volunteers
- 86 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Sepsis, Septic Shock
Sepsis ICU Gut Microbiome Analysis
Sepsis is a life-threatening condition in which the body's response to an infection damages its own organs. This study aims to understand how the bacteria living in the gut change during sepsis and whether patterns of gut…
- Trial name
- SIGMA (NCT07864818)
- Testing
- Naturally Occurring Exposures
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sepsis, Septic Shock
Early Dexmedetomidine and Sympathetic Regulation in Sepsis
The goal of this clinical trial is to learn whether early administration of dexmedetomidine can improve autonomic nervous system regulation and clinical outcomes in adult patients with septic shock.
- Trial name
- DEX-SNS-SEPSIS (NCT07470775)
- Testing
- Dexmedetomidine (DEX)
- Volunteers
- 168 people
- Sponsor
- Sichuan Academy of Medical Sciences
Septic Shock, Sepsis
Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock
The goal of this pilot clinical trial is to determine if conducting a larger study using venous excess ultrasound (VEXUS) to guide fluid management in patients with septic shock is feasible.
- Conditions
- Septic Shock, Sepsis, Shock, Critical Care, Intensive Care
- Trial name
- VESPER (NCT06696391)
- Testing
- Venous Excess Ultrasound (VEXUS)-Guided Management
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Western University, Canada
Acute Respiratory Failure, Critical Illness
ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers
This study will investigate whether a family-centered intervention that has been adapted for patients with critical illness and their caregivers is possible, acceptable, and helpful
- Conditions
- Acute Respiratory Failure, Critical Illness, Sepsis, Hypoxia
- Trial name
- ICU-SUCCEED (NCT07778004)
- Testing
- ICU-SUCCEED, Augmented Usual Care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of North Carolina, Chapel Hill
Sepsis and Septic Shock, Trauma
Fibrinolysis Resistance in Infection and Trauma
Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to…
- Trial name
- FORTITUDE (NCT06680180)
- Testing
- Viscoelastometric assessment of fibrinolysis
- Where
- 4 sites in Australia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anders Aneman