Clinical trials: Septoplasty
Septoplasty
Safety and Performance of ENTACT Septal Staple System for Septoplasty
This is a prospective, multi-center, single arm PMCF study to evaluate the safety and performance of the ENTACT (Next Generation) resorbable staple system for septoplasty in 40 subjects.
- Trial name
- NCT04392583
- Testing
- ENTACT Septal Staple system
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Smith & Nephew, Inc.
Rhinosinusitis, Sinusitis
Clinical Outcomes and Patient Satisfaction With Velnez Versus Nasopore in Nasal Surgery
This clinical trial evaluated two absorbable nasal packing materials - VELNEZ and NASOPORE - in adult patients (18-70 years) who underwent nasal surgery, including septoplasty, FESS, or turbinoplasty.
- Conditions
- Rhinosinusitis, Sinusitis, Chronic Rhino-sinusitis
- Trial name
- NCT07560254
- Testing
- VELNEZ Nasal Pack, NASOPORE Nasal Pack
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Ayu, Inc.
Nasal Obstruction, Septal Defect
Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?
The objective of this study is to compare the effectiveness of batten grafts plus septoplasty and turbinate reduction (intervention arm) compared to septoplasty and turbinate reduction alone (control arm), both in terms of…
- Conditions
- Nasal Obstruction, Septal Defect, Allergic Rhinitis, Nasal Polyps
- Trial name
- NCT05287841
- Testing
- Batten batten graft, Septoplasty, Inferior Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Nasal Septum
Study of the ENTact Septal Staple System for Tissue Approximation During Septoplasty
The purpose of this research study is to learn more about the ENTact™ Septal Staple System device performance and to collect information to support its premarket application.
- Trial name
- NCT00740480
- Where
- 3 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ENTrigue Surgical, Inc.
Cleft Lip and Cleft Palate
Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate
Secondary rhino-septoplasty in unilateral cleft lip and palate is the treatment of choice for the correction of aesthetic deformities and the functional impact on ventilation nasal. It remains a difficult treatment.
- Trial name
- RHINOFENTE (NCT07048418)
- Testing
- Mailing and completing CLEFT-Q and NOSE questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Postoperative Sleep Quality, Nasal Septum Deviation
Anesthesia Type and Postoperative Sleep Quality in Septoplasty
This prospective observational study aims to evaluate the association between routinely applied anesthesia techniques and postoperative sleep quality in adult patients undergoing septoplasty.
- Conditions
- Postoperative Sleep Quality, Nasal Septum Deviation, Septoplasty, Total Intravenous Anesthesia
- Trial name
- ANES-SLEEP (NCT07325799)
- Where
- Turkey (Türkiye)
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Septoplasty
Silastic Sheet Usefulness Following Septoplasty
This study aimed to evaluate the effectiveness of silastic septal splint in reducing the rates of complications, decreasing the post-operative pain, and improving satisfaction in comparison to quilting suturing technique.
- Trial name
- NCT04921462
- Testing
- Septoplasty surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Cough
The Effect-site Concentration of Remifentanil for Preventing Cough During Emergence From Balanced Anesthesia for Nasal Surgery
After nasal surgery, emergence cough or straining will produce venous engorgement and increase bleeding from the surgical site, so the necessity for smooth extubation without severe cough during emergence provides a challenge for…
- Trial name
- NCT01291849
- Testing
- Dixon up-and-down method
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
Nasal Septum Deviation
Disarticulation Septoplasty Versus Classical Way
The objective of this study is to determine which of the two techniques (disarticulation septoplasty versus open surgery) offers the best functional results for correcting symptomatic deviations of the nasal septum.
- Trial name
- DSARTICULATION (NCT07412340)
- Testing
- Comparison of functional improvement in nasal breathing between the two techniques using questionnaires administered to patients by their practitioners in routine practice
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hôpital NOVO
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Nausea and Vomiting, Postoperative, Septoplasty/Septorhinoplasty
Effect of Fresh Gas Flow Differences on Postoperative Nausea and Vomiting
The aim of this study is to investigate the effect of fresh gas flow applied during general anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing septorhinoplasty surgery.
- Trial name
- NCT06952946
- Testing
- 0.5 lt/dk fresh gas flow, 2 lt/dk fresh gas flow, 4 lt/dk fresh gas flow
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Atelectasis, Nasal Septal Deviation
Fresh Gas Flow Rate and Perioperative Lung Aeration Assessed by Lung Ultrasound in Septoplasty
This prospective, single-center observational cohort study evaluated the association between fresh gas flow rate during inhalational anesthesia and perioperative changes in lung aeration in adults undergoing elective surgery for…
- Trial name
- NCT07758517
- Testing
- Fresh Gas Flow Rate of 1 L/min, Fresh Gas Flow Rate of 3 L/min
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Pain
Effectiveness of Bilateral Endoscopic Sphenopalatine Ganglion Block on Postoperative Pain After Septoplasty
The aim of this clinical study will investigate the efficacy of sphenopalatine ganglion block in the treatment of postoperative pain.it will also be learnt whether it reduces the consumption of analgesics in postoperative…
- Trial name
- NCT06695624
- Testing
- Sphenopalatine Ganglion Block
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Airway Complication of Anesthesia, Septoplasty
Video Laryngeal Mask vs. Endotracheal Tube in Septoplasty
This single-center, prospective, observational, comparative study evaluated airway management using the SaCoVLM™ video laryngeal mask airway (VLMA) and a conventional endotracheal tube (ETT) in adult patients undergoing elective…
- Trial name
- NCT06950957
- Testing
- Video Laryngeal Mask Airway (VLMA), Endotracheal Tube (ETT)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Hypotension During Surgery, NGAL
Controlled Hypotension and Renal Injury During Septoplasty
This prospective randomized single-blind study investigated the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on renal injury in patients undergoing septoplasty.
- Conditions
- Hypotension During Surgery, NGAL, Kidney Injury
- Trial name
- NCT07662577
- Testing
- Controlled Hypotension (MAP 50-57 mmHg), Controlled Hypotension (MAP 58-65 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Sinusitis
Endoscopic Sinus Surgery for Refractory Chronic Sinusitis
Chronic sinusitis is a disease involving severe swelling of your facial sinuses and nasal cavity. Chronic sinusitis is a common disorder and roughly 5% of adult men and women have chronic sinusitis in Canada.
- Trial name
- NCT02506426
- Testing
- Endoscopic sinus surgery + Septoplasty, Septoplasty alone
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Deviated Nasal Septum, Nasal Obstruction Septal Deviation Compensatory Inferior Turbinate Hypertrophy
Evaluation of the Outcome of Septoplasty With or Without Inferior Turbinate Reduction
This prospective comparative study aims to evaluate the outcomes of septoplasty with or without inferior turbinate reduction in patients with symptomatic deviated nasal septum.
- Trial name
- NCT07731152
- Testing
- septoplasty, septoplasty with inferior turbinate reduction.
- Volunteers
- 40 people
- Sponsor
- Sohag University
Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
The purpose of this study is to compare the level of pain control in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) to those receiving opioids in the postoperative period after endoscopic sinus surgery (ESS)…
- Trial name
- NCT03605914
- Testing
- diclofenac, Norco
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Nasal Septum Deviation
Effects of Hypotensive Anesthesia on Thiol Disulphide Balance
Oxidative stress at the cellular level and the effects of the antioxidant system on the anesthetic drugs make the anesthesia method more important.
- Trial name
- NCT03501563
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Deviated Nasal Septum
Perioperative Administration of Pregabalin for Pain After Septoplasty
Pregabalin is used for the treatment of neuropathic pain and has shown analgesic efficacy in postoperative pain. The aim of this randomized, double-blinded, placebo-controlled trial was to investigate the efficacy and safety of…
- Trial name
- NCT01370915
- Testing
- Pregabalin (Lyrica)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center