Clinical trials: Serology
Anti-aging, Female
12-Week Efficacy Clinical Study of Serum
65 female adult subjects will be enrolled in the study, recruited according to inclusion and non-inclusion criteria listed above.
- Trial name
- NCT06968416
- Testing
- Standard cleanser，standard moisturizer，standard sunscreen，Investigational serum
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Covid19
COVADIAL - Immunogenicity of COVID-19 Vaccine in Hemodialysis Patients
COVID-19 is a severe disease with poor prognosis in patients receiving in-center haemodialysis (HD). A population-based registry of >4,000 patients with a diagnosis of COVID-19 receiving kidney replacement therapy (either…
- Trial name
- COVADIAL (NCT04728828)
- Testing
- Serological COVID-19 vaccine immunogenicity
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier de Cornouaille
Symptoms Related to Covid-19
Study of Symptoms Linked to Covid-19 in Residents and Professionals in EHPAD, Associated With a Dual Diagnostic Approach by PCR and Serology: a Cohort in Île-de-France.
The main purpose is to study the prevalence of Covid-19 in EHPAD. The primary endpoint will be the combination of PCR results and symptomatology, making it possible to define positive cases in EHPAD, in residents and…
- Trial name
- COVID - EHPAD (NCT04677283)
- Where
- France
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Progressive Supranuclear Palsy, Multiple System Atrophy
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
At present, the diagnosis of Parkinsons disease(PD) mainly relies on clinical symptoms and is easily confused with atypical Parkinsonian syndrome(APS) in the early stages. There is an urgent need for reliable biomarkers.
- Conditions
- Progressive Supranuclear Palsy, Multiple System Atrophy, Parkinson's Disease
- Trial name
- NCT06490926
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
African Trypanosomiases, West African; Trypanosomiasis
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection
The study determines the diagnostic performance and cost of rapid diagnostic tests (RDTs) performed on human African trypanosomiasis clinical suspects in peripheral health centres, whether or not followed by serological and/or…
- Conditions
- African Trypanosomiases, West African; Trypanosomiasis, Sleeping Sickness; West African, Trypanosoma Brucei Gambiense; Infection
- Trial name
- DiTECT-WP2 (NCT03356665)
- Testing
- Rapid diagnostic test (RDT), Serological and molecular tests on DBS
- Where
- 3 sites in Côte d’Ivoire, Democratic Republic of the Congo and 1 more
- Volunteers
- 10,700 people
- Sponsor
- Institut de Recherche pour le Developpement
Allergy to Fish, Allergy
Anisakis Blastocystis Cryptosporidium Fish Serology
Anisakidae frequently infect fish species that are commonly eaten by humans. Some of them are recognized as zoonotic diseases agents, and have a high impact on human health.
- Conditions
- Allergy to Fish, Allergy, Anisakis
- Trial name
- ABCFish2 (NCT02666092)
- Testing
- Questionnaire, Detection of anti-Anisakis and anti-fish antibodies
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Sars-CoV2
Study of Viral Load and Maternal-fetal Serology in the Interpretation of the Vertical Transmission of SARS Cov-2 (COVID-19) During Pregnancy
The study evaluates the distribution of immunological and virological profiles of newborns patients. Mothers of these children have a proven infection to SARS Cov-2 during pregnancy.
- Trial name
- TRANSCOVID (NCT04402918)
- Testing
- biological samples day of delivery
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Ovarian Cancer, Breast Cancer
A Study of Serum Folate Levels in Patients Treated With Olaparib
This is a study investigating folate deficiency (lack of folic acid in the blood) in patients who take the drug olaparib to treat their advanced ovarian or breast cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Folic Acid Deficiency
- Trial name
- NCT04024254
- Testing
- Folic Acid Tablet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rush University Medical Center
SARS-CoV-2 Infection
COVID-10 in the Pediatric Population: SARS-CoV-2 Seropositivity
The purpose of this study was to conduct an epidemiological survey of the pediatric population via SARS CoV-2 IgG antibody testing in order to evaluate the incidence of asymptomatic infection and seropositivity among children and…
- Trial name
- NCT04690114
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Shaare Zedek Medical Center
Non-small Cell Lung Cancer Stage I, Non-small Cell Lung Cancer Stage II
Early Warning Study of Serum Thioredoixn Reductase Activity in Excised Non-small Cell Lung Cancers (EWSOTRILC)
In pre-clinical study, we found that serum thioredoxin reductase activity harbours huge difference after any kind of treatments, so we hypothesis that serum activity of thioredoxin reductase may be a warning markers in excised…
- Conditions
- Non-small Cell Lung Cancer Stage I, Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage IIIA
- Trial name
- NCT01991418
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Hunan Province Tumor Hospital
Non Small Cell Lung Cancer
A Study of Serum Protein Profiling in Patients With Non-Small Cell Lung Cancer Treated With Gefitinib or Erlotinib
We hypothesize that Epidermal growth factor receptor tyrosine kinase inhibitors modulate tumor changes that may be reflected in the alteration of serum proteins.
- Trial name
- NCT00717847
- Where
- Singapore
- Sponsor
- National University Hospital, Singapore
Head and Neck Squamous Cell Carcinoma, Anal Cancer
Blood Biomarkers Based Screening for HPV-driven OPC
The objective of our study is to demonstrate that it is possible to detect and treat human papilloma virus (HPV)-related oropharyngeal cancers (OPC) early using simple blood tests.
- Conditions
- Head and Neck Squamous Cell Carcinoma, Anal Cancer, Human Papilloma Virus
- Trial name
- SCREEN-HPV (NCT06528353)
- Testing
- HPV16-E6 serology and HPV ctDNA
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- UNICANCER
Genital Mycoplasma Infection, High Risk Pregnancy
Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy
Subclinical urogenital infections have been implicated in up to 70% of adverse pregnancy outcome, especially preterm labor and delivery.
- Conditions
- Genital Mycoplasma Infection, High Risk Pregnancy, Preterm Labor
- Trial name
- NCT01281319
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Promyco Diagnostics
Influenza, Acute Lung Injury
Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage
The influenza A/H1N1v pandemic virus causes severe pneumonia that can lead to acute respiratory distress syndrome and death even in healthy young individuals.
- Conditions
- Influenza, Acute Lung Injury, Acute Respiratory Distress Syndrome
- Trial name
- FluBAL (NCT01089400)
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Sars-CoV2
LILLE COVID RESEARCH NETWORK (Covid-19)
The Lille University Hospital developped a research objective common to all the services which took care of patients, "suspected patient", "possible case", "probable case" or "confirmed case" infected with SARS-CoV-2 by…
- Trial name
- LICORNE (NCT04475211)
- Where
- France
- Volunteers
- 757 people
- Sponsor
- University Hospital, Lille
COVID
Caregiver Serological Monitoring Extended Secondarily to Patients With the SARS-CoV-2 Coronavirus
Hospital mortality attributed to SARS-CoV-2 in France increased daily by 28% in the week before confinement. The week following this decision, the daily increase was 30%.
- Trial name
- CoVid3S (NCT04441710)
- Testing
- Questionnaire
- Where
- 4 sites in France
- Volunteers
- 2,777 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Malaria Vivax, Malaria Falciparum
Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and Madagascar
The resilience of P. vivax to malaria elimination efforts is due to its ability to form dormant liver stages (hypnozoites) that reactivate weeks to months after the initial infection causing recurrent episodes of malaria…
- Conditions
- Malaria Vivax, Malaria Falciparum, Plasmodium Vivax, Plasmodium Falciparum
- Trial name
- PvSTATEM (NCT06923592)
- Testing
- PvSeroTAT, Control
- Where
- 2 sites in Ethiopia, Madagascar
- Volunteers
- 19,200 people
- Sponsor
- London School of Hygiene and Tropical Medicine
SARS-CoV-2, COVID-19
Rapid Diagnostic Profiling of SARS-CoV-2 (COVID-19)
The investigators will evaluate the profile of the immune response of Ethiopian population and examine its relationship with the noted low CD4+ T-cell count and underlying immune activation status among participants with COVID-19…
- Trial name
- Profile-Cov (NCT04473365)
- Testing
- Intestinal parasite
- Where
- Ethiopia
- Volunteers
- 838 people, healthy volunteers welcome
- Sponsor
- Mekelle University
Parasitemia, Protozoan Infections
Chagas Disease Diagnostic - Inconclusive Serology
T. cruzi infection affects approximately five million people in Brazil. The diagnosis of the chronic phase of infection is performed by indirect serological methods which, nevertheless, leave inconclusive results.
- Trial name
- NCT00511589
- Testing
- chagas disease diagnostic
- Where
- Brazil
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Maternal Fetal Infection Transmission, COVID-19
Maternal-foetal Transmission of SARS-Cov-2
One case of maternal-fetal transmission of SARS Cov-2 was published (1). Ig M and Ig G were found at two hours after birth of a new born from a mother COVID-19.
- Conditions
- Maternal Fetal Infection Transmission, COVID-19, SARS-CoV 2
- Trial name
- TMF-COVID-19 (NCT04395924)
- Testing
- Diagnosis of SARS-Cov2 by RT-PCR and : IgG, Ig M serologies in the amniotoc fluid, the blood cord and the placenta
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional d'Orléans