Clinical trials: Serology
HCC
Study of Serum Tumor Markers of HBV Associated HCC
In this study, the investigators will detect the expression of four potential HBV-related HCC biomarkers: PGIR,FAM3C,LAMB1 and SDC4 in tumor tissues and peripheral blood, to explore the specific molecular markers for the early…
- Trial name
- NCT05825196
- Testing
- tumor tissue and blood tests
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Hypogonadism
Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure
To further characterize the transfer potential of marketed testosterone gel and new 1.62% formulation.
- Trial name
- NCT00998933
- Testing
- Testosterone gel 1.62%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Polycystic Ovary Syndrome
Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients
The purpose of this study is to evaluate the effect of oral contraceptive on the serum free prostatic specific antigen (PSA)in women with polycystic ovary syndrome(PCOD)compared with cyproterone compound.
- Trial name
- PSA (NCT00955058)
- Testing
- OCP
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Vitamin D Deficiency, Chronic Pain Syndrome
The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial sources, and occurs naturally in a small range of foods.More recently, several reports underlined the impact of vitamin D on the…
- Conditions
- Vitamin D Deficiency, Chronic Pain Syndrome, Inflammatory Response
- Trial name
- NCT01417923
- Testing
- vitamin D
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Adnexal Mass, Borderline Ovarian Epithelial Tumor
Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer
This pilot research trial studies folate receptor in diagnosing ovarian cancer using serum samples from patients with a newly diagnosed pelvic mass or previously diagnosed ovarian cancer.
- Conditions
- Adnexal Mass, Borderline Ovarian Epithelial Tumor, Ovarian Clear Cell Tumor, Ovarian Endometrioid Tumor
- Trial name
- NCT02520115
- Testing
- Dexamethasone, Laboratory Biomarker Analysis, Valproic Acid
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
COVID-19 Infection
COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 Specific Antibody Responses
The study is to investigate the antibody response in the blood and saliva of people with a known COVID-19 infection in the canton of Baselland.
- Trial name
- SEROBL-COVID19 (NCT04483908)
- Testing
- blood draw, fingertip tests for POC assays, saliva collection
- Where
- Switzerland
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
COVID - 19
Retail COVID-19 Study
Despite the availability of vaccines, there remains a need to identify specific immune responses that correlate with protection against SARS-CoV-2 infection.
- Trial name
- NCT06761612
- Testing
- FDA approved mRNA vaccines
- Where
- 20 sites in United States
- Volunteers
- 2,519 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
Papillomavirus Vaccines, Human Immunodeficiency Virus
Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV
The primary objective of this study is to determine the magnitude and breadth of the serum antibody response to the nonavalent HPV vaccine (Gardasil-9) in adults with well-controlled HIV infection.
- Conditions
- Papillomavirus Vaccines, Human Immunodeficiency Virus, Papillomavirus Infection, Serology
- Trial name
- AGO-Gard (NCT05266898)
- Testing
- Human papillomavirus 9-valent vaccine, recombinant, human papillomavirus vaccine, recombinant
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Brucellosis, Spinal Degeneration
Brucella Serology and History of Brucellosis in Patients With Modic Changes Type 1
Objective: This study aims to examine Brucella serology and history of brucellosis in patients with lumbar Modic changes (MCs) type 1, considering results from cross-sectional and case-control comparisons.
- Trial name
- NCT04911283
- Testing
- Brucella serology test, Medical history for brucellosis
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Veysel Delen
COVID-19
A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers
This is a prospective, epidemiological, cohort study to assess the feasibility of screening healthy asymptomatic workers for the presence of severe acute respiratory syndrome SARS-CoV-2 by pharyngeal swaps and serology at…
- Trial name
- NCT04405466
- Testing
- Blood sampling, Throat swab
- Where
- Germany
- Volunteers
- 417 people, healthy volunteers welcome
- Sponsor
- Miltenyi Biomedicine GmbH
Tumor of Lung, Pulmonary Nodule
Prospective Study of Serum Marker LncRNA RP5-977B1 in Pulmonary Nodules
Based on previous studies, this project intends to use prospective studies to select patients identified by imaging as pulmonary nodules to explore the potential of RP5-977B1 in differentiating benign and malignant pulmonary…
- Trial name
- NCT06531850
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
SARS-CoV-2
Screening for COVID-19 and Monitoring of Serological Responses to SARS-CoV-2 in Healthcare Workers
The main objectives of this study are 1) to establish the prevalence of SARS-CoV-2 in asymptomatic healthcare workers (HCWs) in an early phase of community spread as well as 2) to monitor the future spread of the disease by…
- Trial name
- SeCo (NCT04370119)
- Testing
- Nasal swab, Serum testing
- Where
- Germany
- Volunteers
- 1,092 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Parkinson's Disease (PD)
Cross-sectional Study of Vitamin B6 in Parkinson's Disease
The purpose of this study is to estimate the prevalence of abnormal serum levels of vitamin B6, and the associations of those levels with demographic and clinical variables in a randomly selected sample of people living with…
- Trial name
- NCT07430722
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of Rochester
Prostate Cancer
Vitamin D in Treating Patients With Prostate Cancer
RATIONALE: Vitamin D may be effective in treating patients with prostate cancer. PURPOSE: This randomized phase II trial is studying how well 4 different doses of vitamin D works in treating patients with prostate cancer.
- Trial name
- NCT00524680
- Testing
- cholecalciferol
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Roswell Park Cancer Institute
Malaria, Vivax, Malaria,Falciparum
Plasmodium Vivax Among Duffy Negative Population in Cameroon.
Although Plasmodium vivax (P. vivax), one of the five malaria species causing parasites, has the widest geographical distribution, it is rare in sub-Saharan Africa due to the absence of a red blood cell receptor (Duffy antigen)…
- Conditions
- Malaria, Vivax, Malaria,Falciparum, Malaria
- Trial name
- VIBRANT (NCT05058885)
- Where
- Cameroon
- Volunteers
- 900 people
- Sponsor
- University of Dschang
Prostate Cancer
Evaluate Recovery of Testosterone for Patients Using Eligard
The purpose of this study is to determine if testosterone will recover to 90% by year 1 after using Eligard.
- Trial name
- Eligard (NCT01136226)
- Testing
- Eligard (TM)
- Volunteers
- 42 people
- Sponsor
- Chesapeake Urology Research Associates
Influenza -Like Illness, Covid19
Epidemiological Investigation of COVID-19 in Laos Using a One-Health Approach in Human and Animals
The Respiratory infection COVID-19, due to a new coronavirus, SARS-CoV2, appeared in December 2019 in several people who attended the wildlife market in Wuhan, Hubei Province, China.
- Trial name
- LACOVISS (NCT04716543)
- Testing
- ILI and COVID-19 detection
- Volunteers
- 5,400 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Lung Function, Exercise Capacity
Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19
(a) Objectives 1. To assess the full lung function, exercise capacity, quality of life in patients with COVID-19 over 2 years. 2. To assess the longevity of the serology response to SARS-CoV2. 3.
- Conditions
- Lung Function, Exercise Capacity, Quality of Life, Covid19
- Trial name
- NCT04611243
- Testing
- third dose vaccination with CoronaVac vaccine, third dose vaccination with BionTech vaccine, Vaccination with Coronavac vaccine
- Where
- Hong Kong
- Volunteers
- 700 people
- Sponsor
- Chinese University of Hong Kong
Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS
Predicting Peptic Complications Using H. Pylori Serology and Gastric Ultrasound
This observational study aims to evaluate whether combining a simple blood test (H. pylori serology) with a non-invasive abdominal ultrasound can accurately predict severe complications in patients with peptic ulcer disease…
- Conditions
- Peptic Ulcer Disease, HELICOBACTER PYLORI INFECTIONS, Helicobacter Pylori Infection, Peptic Ulcer
- Trial name
- NCT07458490
- Volunteers
- 230 people
- Sponsor
- Assiut University
COVID-19, Rheumatoid Arthritis
COVID-SErology in Rheumatoid Arthritis (COVID-19)
Due to the Covid-19 worldwide outbreak, fragile patients with immune diseases, notably rheumatoid arthritis (RA), have to be even more specifically and carefully followed-up.
- Trial name
- COVID-SERA (NCT04407559)
- Testing
- Serological analyses to be lead on a pre-existing biobank
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Montpellier