Clinical trials: Seroma
NPWT, Latissimus Dorsi Flap
Role of Negative Pressure Wound Therapy in Latissimus Dorsi Flap Donor Site Seroma Prevention
The use of NPWT as a post-operative dressing significantly reduces the incidence of seroma formation after harvesting LD flap.
- Conditions
- NPWT, Latissimus Dorsi Flap, Breast Reconstruction
- Trial name
- NCT02442401
- Testing
- The negative pressure wound therapy
- Volunteers
- 40 people
- Sponsor
- Chulalongkorn University
Modified Radical Mastectomy, Drain Effect
Active Drainage vs. Passive Drainage in MRM
The aim of the study is to compare between active drainage and passive drainage in post-operative seroma formation after modified radical mastectomy in female patient with breast carcinoma as regard of: Primary Outcomes: 1.
- Conditions
- Modified Radical Mastectomy, Drain Effect, Seroma Formation, Brest Cancer
- Trial name
- MRM Drains (NCT07621575)
- Testing
- compare active and passive drain
- Where
- Egypt
- Volunteers
- 157 people
- Sponsor
- MOHAMED GAMAL AHMED ARAKEEB
Seroma
The QUILT Study: Quilting Sutures in Patients Undergoing Breast Cancer Surgery
Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires treatment and…
- Trial name
- QUILT (NCT05272904)
- Testing
- Quilting, Conventional wound closure
- Where
- Netherlands
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Canisius-Wilhelmina Hospital
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
Breast Cancer
Investigating the Use of Drains and (Internal) Quilting Sutures on Seroma Formation Following Mastectomy
Seroma formation is a common complication following breast and axillary surgery for breast cancer. The use of drains is commonplace in practice after mastectomy, although there is evidence to suggest that they do not affect the…
- Trial name
- NCT02668263
- Testing
- Surgery alone, Surgery and Drain(s), Surgery and Quilting Sutures
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- North Tees and Hartlepool NHS Foundation Trust
Surgical Site Infection (SSI), Wound Healing Complication
Prophylactic Use of ciNPWT in Gynecologic Laparotomy
This is a prospective, open-label, non-randomized interventional feasibility study with a nested qualitative analysis. The study exploratively verifies the feasibility of targeted prophylactic closed incision negative pressure…
- Conditions
- Surgical Site Infection (SSI), Wound Healing Complication, Seroma, Hematoma
- Trial name
- NCT07645547
- Testing
- closed incision negative pressure wound therapy (ciNPWT)
- Volunteers
- 30 people
- Sponsor
- University Hospital Hradec Kralove
Infected Seroma After Surgical Procedure
Drain Placement for Seroma Prevention After Mammosite/SAVI Catheter Removal
The proposed study is randomised controlled trial where informed and consenting patients who have a Mammosite/SAVI device placed, are randomized into two groups: a control group that has the device removed in the traditional…
- Trial name
- NCT02390661
- Testing
- Penrose drain placement
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Michigan State University
Breast Cancer
Can Methylprednisoloneacetate Prevent Seroma After Mastectomy for Primary Breast Cancer
A randomised double-blinded study, in which the patients either get methylprednisoloneacetate or saline solution in the mastectomy cavity to evaluate the efficacy of methylprednisoloneacetate in preventing seroma in patients…
- Trial name
- NCT01380912
- Testing
- methylprednisoloneacetate
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital at Herlev
Seroma, Necrosis
Retrospective Analysis of Veritas in Breast Reconstruction
Retrospective data collection of the use of Veritas in breast reconstruction surgery
- Conditions
- Seroma, Necrosis, Infection
- Trial name
- RAVE (NCT01454713)
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Baxter Healthcare Corporation
Postoperative Complications, Hernia
Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?
The purpose of this study is to determine whether drainage after prosthetic repair of incisional abdominal hernias increases or decreases complications such as infection, seromas and hematomas.
- Trial name
- NCT00478348
- Testing
- Prosthetic repair of abdominal incisional hernia
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Lausanne Hospitals
Breast Cancer, Seroma
Seroma Reduction and Drain Free Mastectomy
To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient…
- Conditions
- Breast Cancer, Seroma, Wound Complication
- Trial name
- SARA (NCT04035590)
- Testing
- No drain, With drain
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Zuyderland Medisch Centrum
Seroma
Seroma at the Donor Site of the TRAM Flap, With or Without Quilting Suture: A Comparative Study Using Ultrasound
Patient undergoing breast reconstruction with lower abdominal flap, benefit when points are used for membership (between the aponeurosis of the abdominal flap and underlying muscles) for closing the donor area, where there is…
- Trial name
- STRAMQUSG (NCT01358786)
- Testing
- quilting suture
- Volunteers
- 48 people
- Sponsor
- Federal University of São Paulo
Seroma, Surgical Site Infection
Prevention of Seroma Following Inguinal Lymph Node Dissection With Prophylactic Incisional Negative Pressure Wound Therapy
Inguinal lymph node dissection (ILND) is indicated following metastatic malignant melanoma, and is associated with a high-complication rate, of which many begin with the formation of seroma and ends in complicated wound healing…
- Conditions
- Seroma, Surgical Site Infection, Lymphedema, Quality of Life
- Trial name
- NCT03433937
- Testing
- Negative pressure wound therapy, Micropore tape
- Where
- 4 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Seroma, Hernia, Inguinal
Use of Diathermy Versus Blunt Dissection in TEP for Inguinal Hernia
There is a long debate whether monopoloar or blunt dissection should be adopted in TEP to minimise the chance of seroma formation.
- Trial name
- NCT03665883
- Testing
- Monopolar energy, Blunt dissection
- Where
- China
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Mastectomy
Application Of Autologous Blood Products During Modified Radical Mastectomy
The purpose of this study is to determine if the application of autologous (your own blood) blood products during mastectomy improves wound healing and decreases complications following surgery compared to mastectomy without the…
- Trial name
- NCT00802477
- Testing
- Application of autologous blood products., Standard Modified Radical Mastectomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Marshall University
Breast Cancer - Female
Effects of Negative Pressure Wound Bandaging After Mastectomy
Participant information sheet: Mastectomy is a surgical method used to treat breast cancer. A mastectomy involves the removal of the entire breast. A common postoperative complication after a mastectomy is seroma, i.e.
- Trial name
- NEPTAM (NCT07607366)
- Testing
- PICO negative pressure wound therapy by Smith and Nephew
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Dalarna County Council, Sweden
Drainage, Seroma
Effect of Drainage on the Incidence of Seroma After Laparoscopic Trans Abdominal Preperitoneal Inguinal Hernia Repair
The aim of the study is to evaluate the effect of drainage on the incidence of seroma after laparoscopic transabdominal preperitoneal inguinal hernia repair.
- Conditions
- Drainage, Seroma, Laparoscopic, Trans-abdominal
- Trial name
- NCT07681700
- Testing
- Trans-abdominal preperitoneal repair + Drainage, Trans-abdominal preperitoneal repair
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Seroma, Breast Cancer
The Effect of Thoracal Paravertebral Block on Seroma Reduction in Breast Surgery
Thoracal paravertebral block (TPVB) is a commonly prefferred regional anesthesia technique to provide postoperative analgesia. In addition, the successful use of TPVB is reported for some seroma related pain cases.
- Trial name
- NCT03650868
- Testing
- Thoracal paravertebral block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Ventral Hernia
Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
The aim of this study was to perform a randomised clinical trial comparing the use of closed-suction tubular drains and progressive tension sutures in individuals with large incisional hernias subjected to onlay mesh repair to…
- Trial name
- NCT02163460
- Testing
- Drain, Progressive Tension Sutures
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Oeste do Paraná