Clinical trials: Seroprevalence
Hepatitis E
Exposure to Hepatitis E Virus in Occitania, France
The objective of the proposed work is to determine the seroprevalence of HEV in 2023 in a population of blood donors living in Occitania. Compare the current frequency of anti-HEV IgG and IgM markers with that of 2011.
- Trial name
- EVE (NCT06137313)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Hepatitis E
Seroprevalence Hepatitis E Infection in Healthy Blood Donors
This is a HEV seroprevalence in the health donors in the Canton Ticino study. The pre-donation sampling pouch of each blood donor coming form the Cantone Ticino region will be collected and tested for HEV serology (IgM and IgG).
- Trial name
- NCT03601221
- Testing
- Sample collection
- Where
- Switzerland
- Volunteers
- 1,447 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
HIV Infections, Chikungunya Virus Infection
Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV Infection
Late 2013, the first indigenous cases of chikungunya have been observed in the French Antilles. At the end of May 2014, almost all of the islands of the Caribbean were affected by the outbreak.
- Trial name
- ChikVIH (NCT02553369)
- Testing
- Biological sample collection
- Where
- 2 sites in France
- Volunteers
- 388 people
- Sponsor
- University Hospital Center of Martinique
COVID-19 Respiratory Infection
COVID-19 Seroprevalence in Pregnant Women and Blood Donors
The study aims to measure the SARS-CoV-2 seroprevalence (ie. the proportion of people with antibodies against the virus) in pregnant women and blood donors in an administrative area of France, and to determine whether these…
- Trial name
- CoVERED (NCT04893057)
- Where
- France
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Covid19
Seroprevalence of IgG Antibodies to SARS-CoV-2 (COVID-19) in Primary Health Care Workers and Their Household Contacts
Many uncertainties remain regarding the epidemiological and clinical characteristics of COVID-19, including the number of people exposed to the disease, the persistence of the humoral response and its associated neutralisation…
- Trial name
- COVID-SeroPRIM (NCT04808986)
- Testing
- Serological test for the detection of IgG anti-SARS-CoV-2
- Where
- France
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hepatitis B, Immune Response
Seroprevalence of Hepatitis B and Immune Response to Hepatitis B Vaccination in Chinese College Students
At present, children less than 15 y of age have been regarded as a key group for hepatitis B immunization in China. However, there is not yet special immunization strategy for population above 15 y of age.
- Conditions
- Hepatitis B, Immune Response, Seroprevalence
- Trial name
- NCT01861613
- Testing
- HBV vaccine (Engerix-B, recombinant hepatitis B surface antigen, 20µg/mL/vial, GlaxoSmithKline, Belgium)
- Where
- China
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Hui Zhuang
SARS-CoV-2, Covid19
SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the UZ Brussel Following COVID-19 Vaccination Using an Adenoviral Vector
A novel zoonotic coronavirus was discovered in Wuhan (Hubei Province, China) mid-December 2019 and was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04939402
- Testing
- Serological testing
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Strongyloidiasis, Bone Marrow Transplant Infection
Strongyloides Stercoralis in Bone Marrow Transplant Recipients in the UK
Strongyloidiasis is a worm infection which affects more than 100 million people, mostly in Africa, Asia and Latin America, and can cause severe illness in people with reduced immunity.
- Trial name
- SSSSBMTUK (NCT04709848)
- Testing
- None - standard of care
- Volunteers
- 480 people
- Sponsor
- Imperial College Healthcare NHS Trust
Covid19
COVID-19 Seroprevalence Study in ITM Staff
In Belgium, the corona virus disease 2019 (COVID-19) epidemic is in the growing phase of its second wave. The Belgian crisis cell is balancing between allowing the economy to recover and minimize the disease spread.
- Trial name
- CovAb (NCT04503447)
- Where
- Belgium
- Volunteers
- 330 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Ornithine Transcarbamylase Deficiency, Wilson Disease
Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson Disease
The objective of this observational study is to evaluate the seroprevalence of anti-AAV antibodies in subjects with Ornithine Transcarbamylase (OTC) deficiency, Glycogen Storage Disease Type Ia (GSDIa), and Wilson Disease
- Conditions
- Ornithine Transcarbamylase Deficiency, Wilson Disease, Glycogen Storage Disease Type IA
- Trial name
- NCT04909346
- Where
- 5 sites in United States, Brazil and 3 more
- Volunteers
- 51 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Acute Lymphoblastic Leukemia, Pediatric
Vaccine Immune Recovery After Leukemia
This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children, adolescents, and young adults who recently completed treatment for acute lymphoblastic leukemia…
- Trial name
- VIRAL (NCT05622682)
- Testing
- Observational only: Serology and flow cytometry for ALL cohort participants, Observational only: Infection rates
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Leishmaniasis, Leptospirosis
Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases
Zoonoses and arboviroses refer to a group of diseases transmitted from animals to humans, either directly or indirectly (via mosquitoes, ticks or contact with contaminated environments).
- Conditions
- Leishmaniasis, Leptospirosis, Brucellosis, Q Fever
- Trial name
- SEZAM (NCT06859619)
- Testing
- Peripheral venous blood sample
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
SARS-CoV-2 Seroprevalence
ANC COVID-19 Surveillance
The purpose of this observational study is to determine the seroprevalence of SARS-CoV-2 antibodies in the community with pregnant women aged 15-49 years attending first antenatal care as the sentinel population.
- Trial name
- NCT07021807
- Where
- Zambia
- Volunteers
- 9,111 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
SARS-CoV-2 Infection, Volunteers
Police COVID-19 Serosurvey
The investigators aim to determine the immune status of the employees of the cantonal police of Bern against SARS-CoV-2 over a period of 1 year, and to investigate the risk profile of the study participants and their risk of…
- Conditions
- SARS-CoV-2 Infection, Volunteers, Healthy
- Trial name
- PoliCOV (NCT04643444)
- Testing
- Blood sampling, Online Questionnaire
- Where
- Switzerland
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dengue Fever, Zika
Sylvatic Transmission of Zika, Dengue, and Chikungunya Viruses in Thailand and Cambodia
Background: Zika, dengue, and chikungunya are spread by mosquitos. These diseases have a major impact on public health. This is especially true in in Southeast Asia.
- Conditions
- Dengue Fever, Zika, Vector-Borne Diseases, Chikungunya
- Trial name
- NCT04434846
- Where
- Cambodia
- Volunteers
- 300 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Seroprevalence of SARS-CoV-2 in Asymptomatic Frontline COVID-19 HCWs
This study is about the current knowledge on the immunological changes observed in various healthcare workers in this part of the world, who remained asymptomatic while working in high exposure areas of COVID-19 infection.
- Trial name
- NCT04563247
- Testing
- IgG SARS CoV 2 antibodies
- Where
- Pakistan
- Volunteers
- 970 people
- Sponsor
- Lahore General Hospital
Covid19, SARS-CoV-2 Infection
SARS-CoV-2 Seroprevalence Among Nursing Home Staff and Residents (COVID-19)
Assessment of the seroprevalence and sero-incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) among Nursing Home (NH) residents and staff in Belgium.
- Trial name
- SCOPE (NCT04738695)
- Testing
- Point-of-care rapid anti-SARS-CoV-2 antibody test (Orient Gene Biotech) and Dry Blood Spot collection (Euroimmun)
- Where
- Belgium
- Volunteers
- 3,008 people, healthy volunteers welcome
- Sponsor
- Sciensano
Healthy Volunteers
Defining the COVID-19 Immunity Denominator in the Mekong: a Cross-Sectional Seroprevalence Study of SARS-CoV-2 in HealthyVolunteers
Background: In early 2020, many people thought Cambodia would have a serious COVID-19 outbreak due to the high number of Chinese travelers going to Cambodia.
- Trial name
- NCT04594395
- Where
- 2 sites in Cambodia
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sars-CoV2
Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110)
In mid-February 2020, within the Oise (France) cluster, a case of COVID-19 disease caused by a SARS-CoV2 infection was described among the personnel of the Creail Air Force Base (BA110).
- Trial name
- EpiCovCreil (NCT04404270)
- Testing
- Anti-SARS-CoV2 Serology, Questionnaire, Anti-SARS-CoV2 serological controls and serum neutralization
- Where
- France
- Volunteers
- 1,146 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Covid19
Seroprevalence of COVID-19
Coronavirus disease pandemic has been started in late 2019. Since this date, the number of cases has been increased reaching 32.7 million cases worldwide in 27 September, 2020. .
- Trial name
- cov prevalence (NCT04941053)
- Testing
- laboratory test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University