Clinical trials: Serum Biomarkers
Leukemia, Lymphoma
Serum Histone Succinylation as a Novel Prognostic Biomarker in Hematological Malignancies
4. Study Population 4.1 Inclusion Criteria Case group 1)≥ 18 years old , regardless of gender; 2)Hematological malignancies confirmed by cytology, histology , or molecular biology , who require subsequent anti-tumor treatment …
- Trial name
- succinylation (NCT07131449)
- Testing
- This is observational studies, participants are not assigned an intervention as part of the study.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Diabetic Nephropathies
Serum Immunoglobulin (G) as a Marker of Diabetic Nephropathy
Diabetes mellitus is a chronic disease that affects 366 million people worldwide ( 6.4 % of the adult population ) and is expected to rise to 522 million by 2030 .
- Trial name
- NCT03212755
- Testing
- serum immunoglobulin G level
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2, Metabolic Associated Fatty Liver Disease
Correlation Between Serum Nociceptin and Sympathetic Nerve Activity in Diabetic Patients With MAFLD
This observational study aims to investigate the relationship between serum nociceptin levels and sympathetic nervous system activity in patients with both type 2 diabetes mellitus (T2DM) and metabolic associated fatty liver…
- Trial name
- NCT07663682
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Acute Coronary Syndrome
Magnetic Nanoparticles System in Acute Coronary Syndrome
To improve the sensitivity and specificity of immunoassay, the developing trends are to lower the detection threshold and to minimize the cross reaction.
- Trial name
- NCT02226523
- Where
- 3 sites in Taiwan
- Volunteers
- 455 people
- Sponsor
- Far Eastern Memorial Hospital
Major Depressive Disorder
PKC as Serum Biomarkers for Depression
Inflammation that is mediated by microglia activation plays an important role in the pathogenesis of depression. Microglia activation can lead to an increase in the levels of proinflammatory cytokines, including TNF-α, which…
- Trial name
- NCT04531423
- Testing
- SSRI + golimumab
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Acute Respiratory Distress Syndrome (ARDS), Mechanical Ventilation
Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS
Fibrocyte is a monocyte sub-population involved in fibroproliferation/repair processes and associated with outcome in different diseases.
- Trial name
- IFRA2 (NCT01854424)
- Testing
- Bronchoalveolar lavage (BAL) before day 2 , between days 5-7 and days 10-14 of evolution.
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nasopharyngeal Carcinoma
Prognostic Utility of the Imaging and Biological Signatures in Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) differs from other head and neck malignancies terms of its epidemiology, pathology, and treatment outcome. Although NPC is a radiosensitive tumor, distant recurrence remains a clinical challenge.
- Trial name
- NCT04417985
- Testing
- 18F-FDG PET/CT, MRI
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
COPD Exacerbation
Ferroptosis in Patients With COPD COPD With/Without Risk of Cardiovascular Events. Pathophysiological Implications, Diagnostics and Prognoses. FerrEPOC Study.
Iron metabolism is related to several biochemical and functional factors that have a mayor impact in chronic obstructive pulmonary disease (COPD) such as hypoxia, hypercapnia, oxidative stress, chronic inflammation, cellular…
- Trial name
- FerrEPOC (NCT06102993)
- Testing
- Non-interventional study
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Tumor of Lung, Pulmonary Nodule
Prospective Study of Serum Marker LncRNA RP5-977B1 in Pulmonary Nodules
Based on previous studies, this project intends to use prospective studies to select patients identified by imaging as pulmonary nodules to explore the potential of RP5-977B1 in differentiating benign and malignant pulmonary…
- Trial name
- NCT06531850
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Infection, Intraabdominal, Sepsis Abdominal
Serum Calprotectin in Surgical Septic Patients
To early evaluate the serum levels of calprotectin in patients suffering from intra-abdominal sepsis requiring a surgical treatment.
- Conditions
- Infection, Intraabdominal, Sepsis Abdominal, Biomarker
- Trial name
- NCT06614088
- Testing
- serum calprotectin
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Effects of Walking and Cycling on Serum Physiological Biomarkers
Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals
Physical exercise (walking and cycling) is a potent physiological stimulus that simultaneously alters energy balance, mechanical loading, and metabolic demands in the organism.
- Trial name
- NCT07536659
- Testing
- WALKİNG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli University