Clinical trials: Severe Obesity
Laparoscopic Surgery
Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass
This is a retrospective work on 200 morbid obese patients randomized and categorized into 2 groups according to the treatment method: the laparoscopic sleeve gastrectomy (LSG) and LRYGB groups, within the period from 2014 to 2019…
- Trial name
- NCT05145205
- Testing
- Sleeve gastrectomy, Laparoscopic Roux-en-Y gastric bypass
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Sleep Disturbance, Obesity, Severe
6th Month EWL% After Sleeve Gastrectomy to Get a Better Sleep Quality
Obesity, caused by caloric intake over output, has become a global health problem. The relationship between sleep and obesity is widely discussed in the literature.
- Conditions
- Sleep Disturbance, Obesity, Severe, Surgery
- Trial name
- NCT05608031
- Testing
- Pittsburgh sleep quality index (PSQI) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital
Severe Obesity, Morbid Obesity Requiring Bariatric Surgery
Early Discharge With Hospital-at-Home After Bariatric Surgery and Economic Evaluation.
Bariatric surgery is the most effective treatment for severe obesity and its associated diseases. Advances in surgical techniques, enhanced recovery protocols, and multimodal perioperative care have made earlier hospital…
- Trial name
- BEHOME (NCT07782281)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Corporacion Parc Tauli
Obesity & Overweight, Morbid Obesity
Investigation of the Effects of Whole Body Vibration Application on Muscle Functional Level, Physical Fitness and Respiratory Parameters After Bariatric Surgery
The aim of this study was to investigate the effects of whole body vibration on muscle functional level, physical fitness and respiratory parameters after bariatric surgery.
- Conditions
- Obesity & Overweight, Morbid Obesity, Morbid Obesity Requiring Bariatric Surgery
- Trial name
- NCT07602959
- Testing
- Resistance Training, Whole Body Vibration, Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Obese, Morbid Obesity
Bariatric Surgery During Lockdown, Impact of COVID-19 on Physical and Mental Health
From the beginning of March 2020, lockdown regimens prevented patients with obesity from receiving bariatric surgery. Surgical emergencies and oncological procedures were the only operations allowed in public hospitals.
- Trial name
- NCT04453579
- Testing
- Telephonic interview during the Italian lockdown.
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- University of Rome Tor Vergata
Morbid Obesity
Obesity-related Genes in Taiwanese Undergoing Weight Loss
To investigate: 1. Associations between miRNA and insulin signaling-related gene expressions in abdominal adipose tissues in obese subjects. 2.
- Trial name
- NCT01684280
- Testing
- gender
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Sung Ling Yeh
Morbid Obesity, Steatohepatitis
Identification of Protective and Worsening Steatohepatitis (NASH) Factors
The main aim of this work will be to identify a profile of gene expression by microarray in the liver which might allow to differentiate obese subjects having a normal liver from those with steatohepatitis or steatosis.
- Conditions
- Morbid Obesity, Steatohepatitis, Steatosis
- Trial name
- NCT00914446
- Testing
- hepatic biopsies
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Sleeve Gastrectomy, Morbid Obesity
Bariatric Embolization Before Sleeve Gastrectomy for Super Obese Patients
In patients with severe obesity, bariatric surgery provides consistent and long-term weight loss. BMI ≥50kg / m2 is an independent factor of increased morbidity / mortality in bariatric surgery compared with patients weighing…
- Conditions
- Sleeve Gastrectomy, Morbid Obesity, Bariatric Surgery
- Trial name
- EMBOSLEEVE (NCT05710263)
- Testing
- bariatric embolization
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Morbid Obesity
Comparison of Laparoscopic Sleeve Gastrectomy and Roux-Y-gastric Bypass in the Treatment of Morbid Obesity
The laparoscopic sleeve-gastrectomy (SG) compared to laparoscopic proximal Roux-Y-gastric bypass (PGB) is as successful in the treatment of morbid obesity in the majority of patients.
- Trial name
- NCT00356213
- Testing
- sleeve gastrectomy, Roux-Y-gastric bypass
- Volunteers
- 217 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardio Vascular Disease, Metabolic Syndrome (MetS)
Norwegian Mental Illness Heart Health Study
Norwegian patients with severe mental illnesses (SMI), such as schizophrenia spectrum or bipolar disorder, lose on average 10 years of life compared to mentally healthy individuals. Much of this gap is due to heart disease.
- Conditions
- Cardio Vascular Disease, Metabolic Syndrome (MetS), Severe Mental Disorder, Schizophrenia and Schizophrenia Spectrum Psychosis
- Trial name
- NORMI-Heart (NCT07085923)
- Testing
- Lifestyle Intervention
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Madeleine Elisabeth Angelsen
Morbid Obesity
Sleeve-gastrectomy Efficacy in Morbid Obese Patient With a Focus on the Role of Inflammation
Despite the wide range of studies concerning the positive effects of bariatric surgery on metabolic state of morbid obese patient, it is necessary to further investigate the specific role of the "sleeve-gastrectomy" intervention…
- Trial name
- NCT03559842
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Severe Obesity
Sprayshield as Adhesion Barrier System for Obese Patients
The application of SprayShield during a laparoscopic band removal (first surgical step) will be evaluated to see if the postoperative adhesions between the stomach, the left liver and the diaphragm are not severe, facilitating…
- Trial name
- Sprayshield (NCT02142660)
- Testing
- ablation of gastric
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Morbid Obesity, Opioid-Related Disorders
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of…
- Conditions
- Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
- Trial name
- NCT03925610
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Obesity, Food Addiction
Impact of a Phone-based Cognitive and Behavioral Therapy on Food Addiction in Patients With Severe or Morbid Obesity
Morbid or severe obesity is a chronic pathology of multifactorial etiology that affects 4.3% of the French population. In these patients, eating disorders are frequent and must be managed as they are considered risk factors with…
- Trial name
- ADALOB (NCT04626570)
- Testing
- Cognitive and Behavioral Therapy
- Where
- 9 sites in France
- Volunteers
- 154 people
- Sponsor
- University Hospital, Tours
Esophageal Motility Disorders
Esophageal Dysmotility and Dilatation After Laparoscopic Gastric Banding
The purpose of this study is to determine whether esophageal dysmotility and dilatation is an important complication in the long term follow-up following laparoscopic gastric banding for morbid obesity.
- Trial name
- NCT01234428
- Testing
- Laparoscopic surgery, gastric banding
- Where
- Switzerland
- Volunteers
- 167 people
- Sponsor
- Spital STS AG
Obesity, Morbid Obesity
Energy Balance and Inflammation in Obese Adults Bariatric Surgery Follow-up
The prevalence of obesity is steadily growing in many parts of the world in order to reach epidemic proportions. Changes in signaling pathways state of hunger and satiety contribute to the increase in obesity and metabolic…
- Conditions
- Obesity, Morbid Obesity, Metabolic Syndrome, Inflammation
- Trial name
- NCT02101814
- Testing
- Roux-en-Y gastric bypass (bariatric surgery)
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- Federal University of São Paulo
Diabetes Mellitus Type 2 in Obese
Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.
In patients with type 2 diabetes, Roux-en-Y gastric bypass (RYGB), which excludes a portion of the stomach and the proximal intestine from the alimentary circuit, improves glucose metabolism more rapidly and more extensively than…
- Trial name
- PRECI-Surg (NCT03821636)
- Testing
- Standard Roux-en-Y gastric bypass, Long alimentary limb Roux-en-Y gastric bypass
- Where
- 4 sites in France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Lille
Asthma, Obesity
Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)
Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics.
- Trial name
- GLITZ (NCT00787644)
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Vermont
Morbid Obesity
VAS Correlation With BMI
The aim of the study is to observe if any correlation between Body mass index and VAS values exists in patients who has gone under abdominal surgery.
- Trial name
- NCT02017314
- Testing
- Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University