Clinical trials: Severe Obesity
Eating Behavior, Habits
Goal-directed and Cue-dependent Behavior in Severe Obesity
The current proposal aims to investigate implicit and explicit priming paradigms for changing cue-dependent and goal-directed nutritional behavior in participants with severe obesity before and after bariatric surgery as well as…
- Conditions
- Eating Behavior, Habits, Obesity
- Trial name
- PIT_BS (NCT04187066)
- Testing
- mindset induction
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Behavior
KidQuest Family-Based Weight Control
The purpose of this study is to determine if a family based diet and exercise program is helpful for extremely overweight children aged 8-12, and to compare this approach to standard medical management of severe pediatric obesity.
- Trial name
- NCT00177229
- Testing
- Family-based treatment
- Volunteers
- 192 people
- Sponsor
- University of Pittsburgh
Loss of Control Eating
Loss of Control Eating Following Weight Loss Surgery
This study will test the effectiveness of two distinct behavioral treatments for loss of control eating following bariatric surgery: 1. Behavioral Weight Loss Treatment 2.
- Trial name
- NCT02259322
- Testing
- Standard-of-Care, Behavioral Weight Loss Treatment, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Obesity
Bariatric Surgery Combined With GLP-1 Receptor Agonists Study
Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with single therapies.
- Trial name
- BS-GLP (NCT07336862)
- Testing
- BS-GLP group, BS group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China-Japan Friendship Hospital
Obesity
Lipophilic Organic Polluants and Morbid Obesity
1. To study the kinetics of release after bariatric surgery of selected polluants stored in adipose tissue, looking for clinical and/or predictive factors 2.
- Trial name
- POLOB (NCT01969968)
- Testing
- Lipophilic Organic Polluants dosage
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Morbid Obesity, Intra-Abdominal Hypertension
Correlation of Intra-abdominal Pressure With Gastric and Urinary Bladder Pressures in Patients With Morbid Obesity
The correlations between gastric and urinary bladder pressures with Intra-abdominal pewssure have not been addressed
- Conditions
- Morbid Obesity, Intra-Abdominal Hypertension, Bariatric Surgery Candidate
- Trial name
- NCT04481880
- Testing
- measuring IAP and respiratory parameters
- Volunteers
- 12 people
- Sponsor
- Rambam Health Care Campus
Obesity, Severe Obesity
Prospective Study of an Explainable AI Tool to Support Biliopancreatic Limb Selection in One-Anastomosis Gastric Bypass
This prospective observational cohort study will develop and externally validate a human-supervised, explainable artificial-intelligence decision-support model for analysing factors associated with biliopancreatic limb length…
- Conditions
- Obesity, Severe Obesity, Metabolic Disease
- Trial name
- JI-AI-OAGB (NCT07818317)
- Testing
- One-anastomosis gastric bypass with observed biliopancreatic limb length
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Surgery
Laparoscopic Sleeve Gastrectomy in Severely Obese Adolescents: Effects on Metabolism
Severe obesity (SO), defined as BMI≥95th percentile, has increased worldwide among adolescents. American studies estimated that 1.3-2.8% of 12-19-year-old individuals have a BMI >40 kg/m2 or a BMI >35 kg/m2 with at least one…
- Trial name
- NCT02594514
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Severe Obesity
Effect of Nutritional Intervention and Olive Oil in Severe Obesity
Obesity is a worldwide epidemic with increasing prevalence, specially severe obesity (Body Mass Index (BMI) ≥ 35 kg/m2). It is a multifactorial disease that involves genetic and environmental factors that lead to increased…
- Trial name
- NCT02463435
- Testing
- Nutritional intervention, Nutritional intervention plus olive oil, Olive oil
- Where
- Brazil
- Volunteers
- 229 people
- Sponsor
- Universidade Federal de Goias
Obstructive Sleep Apnea, Obesity
Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)
In this study the investigators will analyze the influence of smoking, benzodizepine use, and obesity among patients with severe Obstructive Sleep Apnea (sOSA).
- Conditions
- Obstructive Sleep Apnea, Obesity, Smoking
- Trial name
- NCT02539264
- Testing
- Smoking, Obesity, Benzodiazepine use
- Volunteers
- 920 people
- Sponsor
- Astes
Obesity, Extreme Obesity
Economic Aspects of Extreme Obesity in Adolescent
Obesity is one of the biggest public health challenges today and in the years to come, particularly due to its rising prevalence in children and adolescents.
- Trial name
- YES (NCT01632098)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Obesity, Morbid
Bariatric Surgery in Children.
Rationale: In the Western world overweight and obesity is an increasing problem both in adults and in children. In youth, it is associated with early death and a number of co-morbidities including metabolic and endocrine changes…
- Trial name
- BASIC (NCT01172899)
- Testing
- laparoscopic adjustable gastric band, Combined life style interventions
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Morbid Obesity
Long-Term Results of a Randomized Trial Comparing Banded-versus-Standard Laparoscopic Roux-en-Y Gastric Bypass
The purpose of the study is comparatively analyze the advantages and disadvantages of banded versus unbanded laparoscopic Roux-en-Y gastric bypass (RYGB).
- Trial name
- NCT01504685
- Testing
- Banded Laparoscopic Roux-en-Y gastric bypass, Unbanded Laparoscopic Roux- en-Y gastric bypass
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Morbid Obesity, Sports Physical Therapy
Nonresponders by the Session Order Factor
Concurrent training (CT, characterised by the inclusion of two exercise modalities), is recognised to improve metabolic syndrome (MetS) markers, but little is known about order session effect on interindividual variability.
- Trial name
- NCT04932642
- Testing
- HIIT+RT experimental group, RT+HIIT experimental group
- Where
- Chile
- Volunteers
- 43 people
- Sponsor
- Cristian Alvarez
Morbid Obesity, Anesthesia Awareness
Comparison of Low Versus Normal Flow Anesthesia on Cerebral Oxygenation and Bispectral Index in Morbidly Obese Patients
Obesity is a chronic disease that affects quality and duration of life negatively. It's not clearly known the effects of low flow anesthesia on cerebral oxygenation with high-risk morbidly obese patients.
- Conditions
- Morbid Obesity, Anesthesia Awareness, Anesthesia Complication
- Trial name
- CerOxygen (NCT03438734)
- Testing
- Regional cerebral oxygen saturation, Bispectral Index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Inonu University
Clinically Severe Obesity, Obesity Recidivism
Adding Malabsorption for Failed Gastric Bypass
The main aim of this study is to analyze and report the preliminary and intermediate term outcomes after laparoscopic revision Roux-en-Y gastric bypass surgery for weight recidivism.
- Conditions
- Clinically Severe Obesity, Obesity Recidivism, Inadequate Initial Weight Loss, Poor Weight Loss
- Trial name
- NCT01040481
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Morbid Obesity
Trial on TAP Block After Bariatric Surgery
Patients undergoing bariatric surgery will be divided randomly into two groups: the first will have TAP block upon completion of surgery and the second groups will not have TAP block.
- Trial name
- NCT03411772
- Testing
- TAP block, Bariatric surgery
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Mansoura University
Depression, Major Depressive Disorder
Diet and Depression
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a…
- Conditions
- Depression, Major Depressive Disorder, Weight Gain, Obesity
- Trial name
- NCT06252701
- Testing
- Reduction of Ultra-processed foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Morbid Obesity
Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients
Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is a common type of surgery in which length of stay and morbidity is intimately associated with post-operative nausea and vomiting (PONV) and recovery of bowel function.
- Trial name
- IV APAP (NCT01460667)
- Testing
- IV acetaminophen, IV normal saline
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- McLaren Regional Medical Center
Morbid Obesity, Hemodynamic Instability
Effects of Low-Flow Anesthesia on Hemodynamic Parameters and Oxygenation in Morbidly Obese Patients
Low-flow anesthesia has been used for years with positive results, but its effects on hemodynamic parameters and oxygenation are not clearly known in high-risk morbidly obese patients who are prone to pulmonary dysfunction…
- Conditions
- Morbid Obesity, Hemodynamic Instability, Bariatric Surgery Candidate
- Trial name
- Oxygenation (NCT03721536)
- Testing
- hemodynamic parameters, arterial blood gase
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Inonu University