Clinical trials: Severe Obesity
Metabolic and Nutritional Complications, Protein Malnutrition
Laparoscopic Revision From Biliopancreatic Diversion to Gastric Bypass
The aim of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional GBP after either failed and/or complicated…
- Conditions
- Metabolic and Nutritional Complications, Protein Malnutrition, Intestinal Malabsorptive Syndrome, Metabolic Bone Disease
- Trial name
- BPD-to-RYGB (NCT01041456)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Obesity
Healthy Weight for Teens
POWER is uniquely positioned to evaluate characteristics of multi-component PWM programs that are associated with "favorable" health outcomes for treatment-seeking youth with obesity.
- Trial name
- NCT03939494
- Testing
- Telehealth Encounter
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Effectiveness of Two Different Body Positions During Facemask Ventilation in Obese Patients
It is important to provide enough oxygen to the patients who are asleep during surgery. One way to do this is by using a mask placed over the face to help them breathe.
- Trial name
- NCT06305273
- Testing
- Head position for face mask ventilation during induction supine, Head position for face mask ventilation during induction head elevated
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Morbid Obesity Requiring Bariatric Surgery
Banded Versus Conventional Laparoscopic Roux-en-Y (GABY)
Banded Versus Conventional Laparoscopic Roux-en-Y Gastric Bypass (GABY). The aim of this novel study is to evaluate, if an additional restrictive silastic ring can avoid dilation of the gastro-entero anastomosis and adjacent…
- Trial name
- GABY (NCT01015469)
- Testing
- Conventional laparoscopic Roux-en-Y gastric bypass, conventional laparoscopic Roux-en-Y gastric bypass with additional restrictive silastic ring
- Where
- 14 sites in Austria, Belgium and 5 more
- Volunteers
- 384 people
- Sponsor
- ClinTrio Ltd.
Obesity
Comparison of a Technology-based System and an In-person Behavioral Weight Loss Intervention in the Severely Obese
The purpose of this study is to examine the effect of an enhanced technology-based system, that involves a wearable device to measure calories burned combined with a website, in comparison to previous versions of similar…
- Trial name
- NCT01537796
- Testing
- In-Person weight loss, FIT weight loss, FIT-BT weight loss
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Severe Obesity Design as BMI > 35kg/m2
Preoxygenation Optimisation in Obese Patients
Oro-tracheal intubation in operating room in obese patients with BMI > 35kg/m2 remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® is more efficient than the…
- Trial name
- PREOPTI-POOP (NCT03106441)
- Testing
- High flow oxygen therapy by nasal cannula. Optiflow®, Facial mask oxygenation in BIPAP ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Morbid Obesity
Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients
Laparoscopic Roux-en-Y gastric bypass (LRYGBP) is a common type of surgery in which length of stay and morbidity is intimately associated with post-operative nausea and vomiting (PONV) and recovery of bowel function.
- Trial name
- IV APAP (NCT01460667)
- Testing
- IV acetaminophen, IV normal saline
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- McLaren Regional Medical Center
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Gastric Bypass After Previous Anti-reflux Surgery
The goal of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional Roux-en-Y gastric bypass (RYGB) after either…
- Trial name
- RYGBafterARS (NCT01041105)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Obesity
Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity
Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations occurring in the post-weight loss setting, including neuroendocrine-mediated changes in appetite/satiety…
- Trial name
- NCT04298203
- Testing
- Phentermine-Topiramate, Meal Replacement Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Morbid Obesity
Tai Chi as Physical Activity for Women With Morbid Obesity
This study investigated the use of Tai Chi as a feasible form of physical activity for women with morbid obesity utilizing an instructional digital video disc (DVD).
- Trial name
- NCT04106661
- Testing
- Tai Chi
- Volunteers
- 17 people
- Sponsor
- Husson University
Morbid Obesity
Effectiveness and Safety Study of LAP-BAND Treatment for Obese Adolescents
The purpose of this study is to determine whether the LAP-BAND system is safe and effective in morbidly obese adolescents.
- Trial name
- NCT00447590
- Testing
- LAP-BAND System
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Apollo Endosurgery, Inc.
Morbid Obesity, Obesity
Bedside Lung Ultrasound to Monitor Lung Recruitment in Obese Patients
Patients with morbid obesity who require a breathing machine (mechanical ventilator) in the Intensive Care Unit (ICU) frequently experience partial lung collapse.
- Conditions
- Morbid Obesity, Obesity, Respiratory Failure, Atelectasis
- Trial name
- NCT07542093
- Volunteers
- 45 people
- Sponsor
- Assiut University
Obesity
Comparison of Gastric Bypass and AspireAssist Aspiration Therapy for Treatment of Morbid Obesity
The purpose of this study is to compare Gastric Bypass and AspireAssist Aspiration Therapy over 5 years of treatment with regards to weight loss, quality of life, complications, adverse events, and health economics.
- Trial name
- NCT02142257
- Testing
- Gastric Bypass, AspireAssist Aspiration Therapy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Blekinge County Council Hospital
Morbid Obesity
"Hachi Barie" Project - A Multidisciplinary Program to Accompany Severely Obese Teenagers in the Weight Loss Process for the Benefit of Their Recruitment Into the Israel Defense Forces
Teenagers with body mass values (BMI) above 35 kg/m2 and co-morbidity are designated for medical disqualification from service in the IDF.
- Trial name
- NCT06102538
- Testing
- # The importance of service in the IDF # Physical activity # Healthy nutrition # Psychological support
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Sheba Medical Center
Child Obesity
STOMP Early Years: A Pilot RCT of an Intensive, Family-Centred, Home Visiting Intervention for Young Children With Severe Obesity
This internal pilot study will determine whether a highly promising primary care based intervention that combines group based parenting skills training and public health nurse home visits with a focus on healthy nutrition…
- Trial name
- STOMP (NCT03219658)
- Testing
- Parenting education sessions
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- The Hospital for Sick Children
Morbid Obesity
Single Anastomosis Sleeve Jejunal (SAS-J) Bypass
The purpose of this study is to determine the efficacy of single anastomoses sleeve jejunal bypass as a treatment for morbid obesity
- Trial name
- NCT02870530
- Testing
- Single Anastomosis Sleeve Jejunal (SAS-J) Bypass
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Type 2 Diabetes, Morbid Obesity
Diabetes Remission After RYGBP and RYGBP With Fundus Resection
The goal of this randomized clinical trial is to evaluate glycemic control in patients with morbid obesity and type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) and RYGBP with fundus resection.
- Conditions
- Type 2 Diabetes, Morbid Obesity, Bariatric Surgery
- Trial name
- NCT05854875
- Testing
- Laparoscopic Roux en Y gastric bypass, Laparoscopic Roux en Y gastric bypass with fundus resection
- Where
- Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
Anorexia Nervosa, Bariatric Surgery
Comparison of the Effects of Weight Changes on Serum Adipokines in Patients Diagnosed With Anorexia Nervosa and Morbid Obesity
In this study, when patients diagnosed with AN started treatment and their weight increased by 10%; On the other hand, it was aimed to compare the changes in serum adipokine levels observed in morbidly obese patients before…
- Conditions
- Anorexia Nervosa, Bariatric Surgery, Weight Change, Body
- Trial name
- NCT04663919
- Testing
- Bariatric surgery-RYGB, Dietary intervention
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Obesity, Extreme Obesity
Economic Aspects of Extreme Obesity in Adolescent
Obesity is one of the biggest public health challenges today and in the years to come, particularly due to its rising prevalence in children and adolescents.
- Trial name
- YES (NCT01632098)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Ulm