Clinical trials: Severe Obesity
Obesity, Memory Deficits
Obesity and Memory, mRNA, Body Composition, Comorbidity Scale
1. Briefly describe the purpose of this protocol. First purpose of the study is to understand the inheritance of morbid obesity. 2. Briefly summarize how participants are recruited.
- Trial name
- 2a (NCT00531505)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Pediatric Obesity
Childhood Obesity, Lifestyle Interventions and Weight Development
Childhood obesity has been associated with increased risk of both continued excess body weight, development of non-communicable lifestyle diseases and impaired mental health.
- Trial name
- NCT05345353
- Testing
- Fat For Fight (FFF), The Aarhus Protocol, The Children's Obesity Clinic Treatment (TCOCT), The Randers Protocol
- Where
- Denmark
- Volunteers
- 2,898 people
- Sponsor
- University of Aarhus
Bariatric Surgery Procedures
Proposal of a Score to Detect the Need for Postoperative Intensive Care Unit Admission After Bariatric Surgery
The purpose of this study is to propose a multi-dimensional score to predict those patients undergoing bariatric surgeries who will be in need for postoperative ICU admission.
- Trial name
- NCT02976649
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Ain Shams University
Obesity, Morbid
Tracheal Intubation in Morbidly Obese (BMI>35) and in Lean (BMI<30) Patients Using McGrath MAC X-Blade
80 lean (BMI<35) and morbidly obese (BMI>35) patients undergoing elective surgery were enrolled in this prospective ransomİzed study were intubated using McGrath MAC X-Blade.
- Trial name
- NCT03759990
- Testing
- lean, obese
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kocaeli University
Morbid Obesity Requiring Bariatric Surgery
Relationship Between Serum Apolipoprotein Levels and Weight Loss in Patients Undergoing Sleeve Gastrectomy for Morbid Obesity
The study looks at whether a specific protein in the blood, called apolipoprotein, can predict how much weight a person might lose after sleeve gastrectomy, a surgery for people with severe obesity.
- Trial name
- NCT07325916
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Yigit DUZKOYLU
Obesity
Prebariatric Surgery Physical Exercise Training in Telehealth
The aim of our study is to evaluate the feasibility of a supervised training session using telehealth in the "Clinique medico-chirurgicale du traitement de l'obésité de Sherbrooke" (CMCTO) and its impact on health, physical…
- Trial name
- TelePreSET (NCT02083913)
- Testing
- Telehealth supervised exercise training
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Université de Sherbrooke
Postoperative Pain
Anterior Abdominal Blocks for Postoperative Pain Control in Obese Patients
The purpose of this study is to compare between two surgical techniques for anterior abdominal wall blocks in obese patients Undergoing Major Gynecological Surgery: Surgical Transversus Abdominis Plane [TAP] block versus Rectus…
- Trial name
- NCT03732027
- Testing
- Surgical Transversus Abdominis Plane Block, Surgical Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Psoriasis, Obesity
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight
The main purpose of this study is to demonstrate that when participants with moderate to severe plaque psoriasis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and…
- Trial name
- TOGETHER-PsO (NCT06588283)
- Testing
- Ixekizumab, Tirzepatide
- Where
- 72 sites in United States, Puerto Rico
- Volunteers
- 281 people
- Sponsor
- Eli Lilly and Company
Morbid Obesity, Surgery
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03021551
- Testing
- Rainbow sensor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Masimo Corporation
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Severe Obesity
Effects of Long Biliopancreatic Limb Versus Long Alimentary Limb in Superobesity, a Randomized Study
Surgical bypassing of a longer section of the small bowel (when doing a gastric bypass operation) gives better results on body weight in the superobese.
- Trial name
- BMI>50 (NCT02033577)
- Testing
- Distal gastrojejunal bypass, RYGB
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Aleris Obesity
Obesity, Morbid
Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity
This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.
- Trial name
- NCT05611697
- Testing
- Single anastomosis sleeve ileal bypass, Sleeve gastrectomy
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
Morbid Obesity
Follow-up of Adolescent Bariatric Surgery
Very little information is available about extremely obese (body mass index [BMI] > 40 kg/m2) adolescents. The purpose of the Follow up of Adolescent Bariatric Surgery (FABS) study is to collect information obtained during the…
- Trial name
- FABS (NCT00776776)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Morbid Obesity
Effect of Bariatric Surgery on Bile Acid Homeostasis
The purpose of this study is to evaluate the effect of bariatric surgery in bile acid homeostasis and its interrelationship with the metabolic changes induced by the surgery.
- Trial name
- NCT02366624
- Where
- Chile
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Feeding and Eating Disorders
Impact of COVID-19 Lockdown on Obesity and Eating Behaviors
COVID-19 lockdown presents particular challenges for people living with obesity. Indeed during this period, the lifestyle was deeply modified: diet, activity, and sleep behaviours, home office, take care of child, social…
- Trial name
- CIO (NCT04431284)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
Cholecystitis, Chronic
Bikini Scarless Laparoscopic Cholecystectomy for Morbid Obesity as a Day Case.
Background: Bikini line laparoscopic cholecystectomy is a safe method, used as a scarless cosmetic port technique for gall bladder diseases in morbid obese patients as a day case.
- Trial name
- NCT04836598
- Testing
- laparoscopic cholecystectomy
- Where
- 4 sites in Egypt, Saudi Arabia
- Volunteers
- 3 people
- Sponsor
- Zagazig University
Morbid Obesity, Bariatric Surgery Candidate
Intravenous Lidocaine in Bariatric Surgery.
Although peroperative intravenous lidocaine has been shown to be useful in early recovery after colorectal surgery, its beneficial effect on the specific population of obese patients scheduled for bariatric surgery remained…
- Trial name
- XYLOBAR (NCT03211455)
- Testing
- Lidocaine, isotonic saline
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Caen
Severe Preeclampsia
Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia
There is still no evidence of the appropriate dose to be used. Serum magnesium sulfate concentration is not measured regularly, thus we may be using sub-therapeutic level or reaching a toxic level.Overweight and obese women have…
- Trial name
- NCT06486025
- Testing
- maintenance magnesium sulphate1g/h, maintenance magnesium sulphate2g/h
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Bariatric Surgery, Morbid Obesity
The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery
Bariatric guidelines recommend preoperative weight loss of 5% to reduce the risk of surgical complications. However, results in the literature on the improvement of surgical procedure and outcomes are still conflicting.
- Trial name
- NCT04433338
- Testing
- 14-day Low Calorie Diet
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Rijnstate Hospital
COVID-19 Pandemic, Obesity
Obesity: an Underappreciate Risk Factor for Severe Form of COVID-19
Our study has the objective of identifying the epidemiological profil of the patients, as well as, the clinical, radiological and prognosis of obese patients with covid 19.
- Trial name
- NCT05771857
- Testing
- Obesity
- Where
- Morocco
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital