Clinical trials: Severe Obesity
Obesity, Diabetes
A Patient-Centered PaTH to Addressing Diabetes
The overarching goal of this proposal is to understand the comparative effectiveness of obesity counseling as covered by CMS in improving weight loss for adults either with or at high risk of type 2 diabetes.
- Conditions
- Obesity, Diabetes, Covid19
- Trial name
- NCT02788903
- Testing
- Weight Counseling
- Volunteers
- 2,622,164 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
GERD, Morbid Obesity
Management of Reflux After Sleeve Using Stretta
Gastroesophageal reflux disease (GERD) is a frequently seen entity after sleeve gastrectomy. Management of GERD after sleeve is difficult given limited treatment modalities.
- Trial name
- MaRSS (NCT02637713)
- Testing
- Stretta, Radiofrequency (RF) Energy to the LES (Stretta Procedure)
- Where
- 13 sites in United States
- Volunteers
- 5 people
- Sponsor
- Montefiore Medical Center
Obesity, Morbid Obesity
Bariatric Embolization of Arteries With Imaging Visible Embolics (BEATLES)
The BEATLES study is an investigator-initiated, prospective, double-blinded, randomized, sham-controlled study that will assess the impact of bariatric embolization on the systemic levels of obesity-related hormones and, as a…
- Conditions
- Obesity, Morbid Obesity, Weight Loss
- Trial name
- BAE2 (NCT04197336)
- Testing
- Bariatric Embolization of Arteries with imaging visible Embolics
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity and Diabetes Mellitus, Type 2
A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus
The purpose of this study is to assess the effects of JNJ-64565111 compared with placebo in severely obese Type 2 Diabetes Mellitus (T2DM) participants after 12 weeks of treatment on: the percentage change in body weight from…
- Trial name
- NCT03586830
- Testing
- JNJ-64565111 Dose Level 1, JNJ-64565111 Dose Level 2, JNJ-64565111 Dose Level 3
- Where
- 27 sites in United States
- Volunteers
- 196 people
- Sponsor
- Janssen Research & Development, LLC
Diabetes, Morbid Obesity
Closed Incision Negative Pressure Wound Therapy vs. Foam as Post Operative Dressing
The primary objective is to assess the frequency of a wound healing complication, in a closed incisional wound in a "high risk" surgical incision when treated with Negative Pressure Wound Therapy versus a highly absorbent…
- Conditions
- Diabetes, Morbid Obesity, Lymphedema, Orthopedic Disorder
- Trial name
- NCT05427916
- Testing
- Avance Solo, Optifoam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Morbid
Safety and Effectiveness Study of The Swedish Adjustable Gastric Band (SAGB) in the Treatment of Morbid Obesity
The purpose of this study is to determine whether the Swedish Adjustable Gastric Band (SAGB) is safe, and effective in achieving weight loss in patients with Morbid Obesity.
- Trial name
- NCT00166205
- Testing
- Swedish Adjustable Gastric Band
- Where
- 12 sites in United States
- Volunteers
- 276 people
- Sponsor
- Ethicon Endo-Surgery
Morbid Obesity
Surgical Conditions During Laparoscopic Bariatric Surgery
Obesity affects more than 78 million adults in the United States and it is estimated that 35% of the US population is obese. Currently, more than 179,000 bariatric procedures are performed in the US each year with the majority of…
- Trial name
- NCT02703909
- Testing
- Rocuronium, Insufflation pressure
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Missouri-Columbia
Obstructive Sleep Apnea, Obesity
Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity
The purpose of this study is to develop a data driven system for persons with severe obesity sleep apnea that utilizes remote monitoring with health coaching to create behavior changes aimed at improving health and quality of…
- Trial name
- NCT05343000
- Testing
- Home-based pulmonary rehabilitation (PR) system
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic